^Smith TG, Robbins PA, Ratcliffe PJ. The human side of hypoxia-inducible factor. Br. J. Haematol. May 2008, 141 (3): 325–34. PMC 2408651. PMID 18410568. doi:10.1111/j.1365-2141.2008.07029.x.
^Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. U.S.A. June 1995, 92 (12): 5510–4. PMC 41725. PMID 7539918. doi:10.1073/pnas.92.12.5510.
^Jiang BH, Rue E, Wang GL, Roe R, Semenza GL. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J. Biol. Chem. July 1996, 271 (30): 17771–8. PMID 8663540. doi:10.1074/jbc.271.30.17771.
^Zhulin IB, Taylor BL, Dixon R. PAS domain S-boxes in Archaea, Bacteria and sensors for oxygen and redox. Trends Biochem. Sci. September 1997, 22 (9): 331–3. PMID 9301332. doi:10.1016/S0968-0004(97)01110-9.
^Ponting CP, Aravind L. PAS: a multifunctional domain family comes to light. Curr. Biol. November 1997, 7 (11): R674–7. PMID 9382818. doi:10.1016/S0960-9822(06)00352-6.
^Yang J, Zhang L, Erbel PJ, Gardner KH, Ding K, Garcia JA, Bruick RK. Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor. J. Biol. Chem. October 2005, 280 (43): 36047–54. PMID 16129688. doi:10.1074/jbc.M501755200.
^Min JH, Yang H, Ivan M, Gertler F, Kaelin WG, Pavletich NP. Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling. Science. June 2002, 296 (5574): 1886–9. PMID 12004076. doi:10.1126/science.1073440.
^Freedman SJ, Sun ZY, Poy F; et al. Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha. Proc. Natl. Acad. Sci. U.S.A. April 2002, 99 (8): 5367–72. PMC 122775. PMID 11959990. doi:10.1073/pnas.082117899. 引文格式1维护:显式使用等标签 (link)
^Benizri E, Ginouvès A, Berra E. The magic of the hypoxia-signaling cascade. Cell. Mol. Life Sci. April 2008, 65 (7-8): 1133–49. PMID 18202826. doi:10.1007/s00018-008-7472-0.
^Formenti F, Constantin-Teodosiu D, Emmanuel Y, Cheeseman J, Dorrington KL, Edwards LM, Humphreys SM, Lappin TR, McMullin MF, McNamara CJ, Mills W, Murphy JA, O'Connor DF, Percy MJ, Ratcliffe PJ, Smith TG, Treacy M, Frayn KN, Greenhaff PL, Karpe F, Clarke K, Robbins PA. Regulation of human metabolism by hypoxia-inducible factor. Proc. Natl. Acad. Sci. U.S.A. July 2010, 107 (28): 12722–7. PMC 2906567. PMID 20616028. doi:10.1073/pnas.1002339107.
^Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. May 1999, 399 (6733): 271–5. PMID 10353251. doi:10.1038/20459.
^Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology (Bethesda). August 2004, 19 (4): 176–82. PMID 15304631. doi:10.1152/physiol.00001.2004.
^Wong W, Goehring AS, Kapiloff MS, Langeberg LK, Scott JD. mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha. Sci Signal. 2008, 1 (51): ra18. PMC 2828263. PMID 19109240. doi:10.1126/scisignal.2000026.
^ 14.014.1van Uden P, Kenneth NS, Rocha S. Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. Biochem J. 2008, 412 (3): 477–484 [2022-03-25]. PMC 2474706. PMID 18393939. doi:10.1042/BJ20080476. (原始内容于2019-09-02).
^Haase VH. Hypoxic regulation of erythropoiesis and iron metabolism. Am. J. Physiol. Renal Physiol. July 2010, 299 (1): F1–13. PMC 2904169. PMID 20444740. doi:10.1152/ajprenal.00174.2010.
^Bruegge K, Jelkmann W, Metzen E. Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases. Curr. Med. Chem. 2007, 14 (17): 1853–62. PMID 17627521. doi:10.2174/092986707781058850.
^Cases A. The latest advances in kidney diseases and related disorders. Drug news & perspectives. December 2007, 20 (10): 647–54. ISSN 0214-0934. PMID 18301799.
^Hsieh MM, Linde NS, Wynter A, Metzger M, Wong C, Langsetmo I, Lin A, Smith R, Rodgers GP, Donahue RE, Klaus SJ, Tisdale JF. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques. Blood. September 2007, 110 (6): 2140–7. PMC 1976368. PMID 17557894. doi:10.1182/blood-2007-02-073254.
^KangAe Lee, Huafeng Zhang, David Z. Qian, Sergio Rey, Jun O. Liu, Gregg L. Semenza. Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization. Proceedings of the National Academy of Sciences. 2009-10-20, 106 (42): 17910–17915 [2018-04-02]. doi:10.1073/pnas.0909353106.
^Syed Alwi SS, Cavell BE, Telang U, Morris ME, Parry BM, Packham G. In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study. Br. J. Nutr. November 2010, 104 (9): 1288–96. PMID 20546646. doi:10.1017/S0007114510002217.
^Semenza GL. Evaluation of HIF-1 inhibitors as anticancer agents. Drug Discov. Today. October 2007, 12 (19-20): 853–9. PMID 17933687. doi:10.1016/j.drudis.2007.08.006.
^Melillo G. Inhibiting hypoxia-inducible factor 1 for cancer therapy. Mol. Cancer Res. September 2006, 4 (9): 601–5. PMID 16940159. doi:10.1158/1541-7786.MCR-06-0235.