^ 1.01.11.21.31.41.51.61.7Ondansetron Hydrochloride. The American Society of Health-System Pharmacists. [February 11, 2017]. （原始内容于2016-05-03）.
^Schnadower, D; Finkelstein, Y; Freedman, SB. Ondansetron and probiotics in the management of pediatric acute gastroenteritis in developed countries.. Current Opinion in Gastroenterology. January 2015, 31 (1): 1–6. PMID 25333367. doi:10.1097/mog.0000000000000132.
^Freedman, SB; Ali, S; Oleszczuk, M; Gouin, S; Hartling, L. Treatment of acute gastroenteritis in children: an overview of systematic reviews of interventions commonly used in developed countries.. Evidence-based child health : a Cochrane review journal. July 2013, 8 (4): 1123–37. PMID 23877938. doi:10.1002/ebch.1932.
^Sutton, M; Mounsey, AL; Russell, RG. FPIN's Clinical Inquiries. Treatment of motion sickness.. American Family Physician. 15 July 2012, 86 (2): 192–5. PMID 22962932.
^Miloro, ed. by Michael. Peterson's principles of oral and maxillofacial surgery. 3rd. Shelton, CT: People's Medical Pub. House-USA. 2012: 86 [2018-02-03]. ISBN 978-1-60795-111-7. （原始内容于2016-02-01）.
^Sneader, Walter. Drug discovery: a history Rev. and updated. Chichester: Wiley. 2005: 217 [2018-02-03]. ISBN 978-0-471-89979-2. （原始内容于2016-02-01）.
^WHO Model List of Essential Medicines (19th List) (PDF). World Health Organization. April 2015 [8 December 2016]. （原始内容 (PDF)于2016-12-13）.
^Ondansetron. International Drug Price Indicator Guide. [26 January 2016]. （原始内容于2017-05-10）.
外部連結
U.S. National Library of Medicine: Drug Information Portal – Ondansetron （页面存档备份，存于互联网档案馆）
Template:5-HT3 antagonists
一月 30, 2023
昂丹司琼, 昂丹司瓊, ondansetron, 常見商品名, zofran, 是一種用於減少手術, 化療, 放射治療後, 惡心嘔吐的藥物, 亦可用於治療腸胃炎, 但對於動暈症幾乎無治療效果, 本品可經口服給藥, 也可以肌肉注射或靜脈注射使用, 臨床資料商品名, 英语, drug, nomenclature, zofran, ondisolv, othersahfs, 英语, american, society, health, system, pharmacists, drugs, commonographmed. 昂丹司瓊 Ondansetron 常見商品名 Zofran 是一種用於減少手術 化療 放射治療後 惡心嘔吐的藥物 1 亦可用於治療腸胃炎 2 3 但對於動暈症幾乎無治療效果 4 本品可經口服給藥 也可以肌肉注射或靜脈注射使用 1 昂丹司琼臨床資料商品名 英语 Drug nomenclature Zofran Ondisolv othersAHFS 英语 American Society of Health System Pharmacists Drugs comMonographMedlinePlusa601209懷孕分級澳 B1给药途径by mouth rectal IV IMATC碼A04AA01 WHO 法律規範狀態法律規範澳 限医生处方 S4 加 处方药 only 英 处方药 only POM 美 处方药 only 藥物動力學數據生物利用度 60 血漿蛋白結合率70 76 药物代谢Liver CYP3A4 CYP1A2 CYP2D6 生物半衰期5 7 hours排泄途徑Kidney识别信息IUPAC命名法 RS 9 methyl 3 2 methyl 1H imidazol 1 yl methyl 2 3 dihydro 1H carbazol 4 9H oneCAS号99614 02 5 PubChem CID4595IUPHAR BPS2290DrugBankDB00904 ChemSpider4434 UNII4AF302ESOSKEGGD00456 ChEMBLChEMBL46 CompTox Dashboard 英语 CompTox Chemicals Dashboard EPA DTXSID8023393ECHA InfoCard100 110 918化学信息化学式C 18H 19N 3O摩尔质量293 4 g mol3D模型 JSmol 英语 JSmol 交互式图像SMILES O C3c2c1ccccc1n c2CCC3Cn4ccnc4C CInChI InChI 1S C18H19N3O c1 12 19 9 10 21 12 11 13 7 8 16 17 18 13 22 14 5 3 4 6 15 14 20 16 2 h3 6 9 10 13H 7 8 11H2 1 2H3 Key FELGMEQIXOGIFQ UHFFFAOYSA N 常見的副作用包括腹瀉 頭痛 嗜睡和皮膚搔癢 1 嚴重的話可能誘發QT波延長或是全身性過敏反應 1 妊娠期間用藥似為安全 但相關證據仍不足夠 1 此藥物是一種高專一性的血清素5 HT3受體拮抗劑 英语 5 HT3 antagonist 1 並不會針對多巴胺受體或蕈鹼類受器 5 昂丹司瓊在1990年首次被作為藥物使用 6 本品列名於世界卫生组织基本药物标准清单 該清單紀錄了一般衛生體系最需要的藥物 7 目前已是學名藥 1 其於開發中國家的每劑注射劑型批發價約介於0 1到0 76美金 8 在美國 每顆藥物大約花費1 37美金 1 參考文獻 编辑 1 0 1 1 1 2 1 3 1 4 1 5 1 6 1 7 Ondansetron Hydrochloride The American Society of Health System Pharmacists February 11 2017 原始内容存档于2016 05 03 Schnadower D Finkelstein Y Freedman SB Ondansetron and probiotics in the management of pediatric acute gastroenteritis in developed countries Current Opinion in Gastroenterology January 2015 31 1 1 6 PMID 25333367 doi 10 1097 mog 0000000000000132 Freedman SB Ali S Oleszczuk M Gouin S Hartling L Treatment of acute gastroenteritis in children an overview of systematic reviews of interventions commonly used in developed countries Evidence based child health a Cochrane review journal July 2013 8 4 1123 37 PMID 23877938 doi 10 1002 ebch 1932 Sutton M Mounsey AL Russell RG FPIN s Clinical Inquiries Treatment of motion sickness American Family Physician 15 July 2012 86 2 192 5 PMID 22962932 Miloro ed by Michael Peterson s principles of oral and maxillofacial surgery 3rd Shelton CT People s Medical Pub House USA 2012 86 2018 02 03 ISBN 978 1 60795 111 7 原始内容存档于2016 02 01 Sneader Walter Drug discovery a history Rev and updated Chichester Wiley 2005 217 2018 02 03 ISBN 978 0 471 89979 2 原始内容存档于2016 02 01 WHO Model List of Essential Medicines 19th List PDF World Health Organization April 2015 8 December 2016 原始内容存档 PDF 于2016 12 13 Ondansetron International Drug Price Indicator Guide 26 January 2016 原始内容存档于2017 05 10 外部連結 编辑U S National Library of Medicine Drug Information Portal Ondansetron 页面存档备份 存于互联网档案馆 Template 5 HT3 antagonists 取自 https zh wikipedia org w index php title 昂丹司琼 amp oldid 69174103, 维基百科，wiki，书籍，书籍，图书馆，
