^ 1.01.11.21.31.41.5Cole et al. Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J. Exp. Med. 187: 2009-2021, 1998.
^Sauty, A., Dziejman, M., Taha, R. A., Iarossi, A. S., Neote, K., Garcia-Zepeda, E. A., Hamid, Q., Luster, A. D. (1999) The T cell-specific CXC chemokines IP-10, MIG, and I-TAC are expressed by activated human bronchial epithelial cells J. Immunol. 162,3549-3558
^Gasperini, S., Marchi, M., Calzetti, F., Laudanna, C., Vicentini, L., Olsen, H., Murphy, M., Liao, F., Farber, J., Cassatella, M. A. (1999) Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils J. Immunol. 162,4928-4937.
^Tensen, C. P., Flier, J., Van Der Raaij-Helmer, E. M., Sampat-Sardjoepersad, S., Van Der Schors, R. C., Leurs, R., Scheper, R. J., Boorsma, D. M., Willemze, R. (1999) Human IP-9: a keratinocyte-derived high-affinity CXC-chemokine ligand for the IP-10/MIG receptor (CXCR3) J. Invest. Dermatol. 112,716-72.
^Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996 Sep 1;184(3):963-9.
^Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J Biol Chem. 1998 Jul 17;273(29):18288-91.
^Loetscher P, Pellegrino A, Gong JH, Mattioli I, Loetscher M, Bardi G, Baggiolini M, Clark-Lewis I. The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3. J Biol Chem. 2001 Feb 2;276(5):2986-91
外部链接编辑
Charo IF, Ransohoff RM. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med. 2006 Feb 9;354(6):610-21.（页面存档备份，存于互联网档案馆）
十二月 06, 2023
cxcl11, 英語, chemokine, motif, ligand, 是一小分子的细胞因子属于cxc趋化因子家族, 又被称作, 干扰素诱导的t细胞a趋化因子, interferon, inducible, cell, alpha, chemoattractant, chemokine, motif, ligand, 11pdb, rendering, based, 1rjt, 有效结构pdb, 直系同源检索, pdbe, rcsbpdb查询代码列表1rjt标识代号, h174, scyb11, scyb9b,. CXCL11 英語 Chemokine C X C motif ligand 11 是一小分子的细胞因子属于CXC趋化因子家族 1 又被称作 干扰素诱导的T细胞a趋化因子 Interferon inducible T cell alpha chemoattractant I TAC 1 Chemokine C X C motif ligand 11PDB rendering based on 1rjt 有效结构PDB 直系同源检索 PDBe RCSBPDB查询代码列表1RJT标识代号CXCL11 H174 I TAC IP 9 IP9 SCYB11 SCYB9B b R1扩展标识遗传学 604852 鼠基因 1860203 同源基因 3944 GeneCards CXCL11 Gene基因本体论描述分子功能 chemokine activity细胞成分 extracellular region extracellular space生物过程 chemotaxis inflammatory response immune response signal transduction cell cell signalingSources Amigo QuickGORNA表达模式更多表达数据直系同源体物种人类小鼠Entrez637356066EnsemblENSG00000169248n aUniProtO14625Q9JHH5mRNA序列NM 005409NM 019494 1蛋白序列NP 005400NP 062367 1基因位置Chr 4 76 95 76 96 Mbn aPubMed查询 1 2 查论编 目录 1 表达 2 受体 3 功能 4 参见 5 参考文献 6 外部链接表达 编辑在白细胞 胰腺和肝脏中表达水平高 在胸腺 脾和肺有中等水平的表达 在小肠 胎盘和前列腺中表达水平低 1 干扰素伽玛和干扰素 b可以在单核细胞 1 支气管上皮细胞 2 中性粒细胞 3 角质形成细胞 4 和内皮细胞诱导CXCL11的表达 受体 编辑CXCL11结合趋化因子受体CXCR3而起其细胞趋化作用 1 5 6 CXCL11也可以结合到趋化因子受体CCR3上而阻止CCR3配体的结合 7 功能 编辑CXCL11对活化的T细胞 中性粒细胞和单核细胞有细胞趋化作用 1 参见 编辑趋化因子 CXCR3 CXCL9 CXCL10参考文献 编辑 1 0 1 1 1 2 1 3 1 4 1 5 Cole et al Interferon inducible T cell alpha chemoattractant I TAC a novel non ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3 J Exp Med 187 2009 2021 1998 Sauty A Dziejman M Taha R A Iarossi A S Neote K Garcia Zepeda E A Hamid Q Luster A D 1999 The T cell specific CXC chemokines IP 10 MIG and I TAC are expressed by activated human bronchial epithelial cells J Immunol 162 3549 3558 Gasperini S Marchi M Calzetti F Laudanna C Vicentini L Olsen H Murphy M Liao F Farber J Cassatella M A 1999 Gene expression and production of the monokine induced by IFN gamma MIG IFN inducible T cell alpha chemoattractant I TAC and IFN gamma inducible protein 10 IP 10 chemokines by human neutrophils J Immunol 162 4928 4937 Tensen C P Flier J Van Der Raaij Helmer E M Sampat Sardjoepersad S Van Der Schors R C Leurs R Scheper R J Boorsma D M Willemze R 1999 Human IP 9 a keratinocyte derived high affinity CXC chemokine ligand for the IP 10 MIG receptor CXCR3 J Invest Dermatol 112 716 72 Loetscher M Gerber B Loetscher P Jones SA Piali L Clark Lewis I Baggiolini M Moser B Chemokine receptor specific for IP10 and mig structure function and expression in activated T lymphocytes J Exp Med 1996 Sep 1 184 3 963 9 Weng Y Siciliano SJ Waldburger KE Sirotina Meisher A Staruch MJ Daugherty BL Gould SL Springer MS DeMartino JA Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors J Biol Chem 1998 Jul 17 273 29 18288 91 Loetscher P Pellegrino A Gong JH Mattioli I Loetscher M Bardi G Baggiolini M Clark Lewis I The ligands of CXC chemokine receptor 3 I TAC Mig and IP10 are natural antagonists for CCR3 J Biol Chem 2001 Feb 2 276 5 2986 91外部链接 编辑Charo IF Ransohoff RM The many roles of chemokines and chemokine receptors in inflammation N Engl J Med 2006 Feb 9 354 6 610 21 页面存档备份 存于互联网档案馆 取自 https zh wikipedia org w index php title CXCL11 amp oldid 64125045, 维基百科，wiki，书籍，书籍，图书馆，
