^Simoni M, Gromoll J, Nieschlag E. The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology. Endocr. Rev. December 1997, 18 (6): 739–73. PMID 9408742. doi:10.1210/er.18.6.739.
延伸阅读编辑
de la Chapelle A. Disease gene mapping in isolated human populations: the example of Finland.. J. Med. Genet. 1993, 30 (10): 857–65. PMC 1016570. PMID 8230163. doi:10.1136/jmg.30.10.857.
Amsterdam A, Hanoch T, Dantes A; et al. Mechanisms of gonadotropin desensitization.. Mol. Cell. Endocrinol. 2003, 187 (1–2): 69–74. PMID 11988313. doi:10.1016/S0303-7207(01)00701-8. 引文格式1维护：显式使用等标签 (link)
Simoni M, Nieschlag E, Gromoll J. Isoforms and single nucleotide polymorphisms of the FSH receptor gene: implications for human reproduction. Hum. Reprod. Update. 2003, 8 (5): 413–21. PMID 12398222. doi:10.1093/humupd/8.5.413.
Delbaere A, Smits G, Olatunbosun O; et al. New insights into the pathophysiology of ovarian hyperstimulation syndrome. What makes the difference between spontaneous and iatrogenic syndrome?. Hum. Reprod. 2004, 19 (3): 486–9. PMC 2891954. PMID 14998941. doi:10.1093/humrep/deh124. 引文格式1维护：显式使用等标签 (link)
Bose CK. Role of nerve growth factor and FSH receptor in epithelial ovarian cancer. Reprod. Biomed. Online. 2005, 11 (2): 194–7. PMID 16168216. doi:10.1016/S1472-6483(10)60958-3.
Wunsch A, Sonntag B, Simoni M. Polymorphism of the FSH receptor and ovarian response to FSH. Ann. Endocrinol. (Paris). 2007, 68 (2–3): 160–6. PMID 17544358. doi:10.1016/j.ando.2007.04.006.
Kelton CA, Cheng SV, Nugent NP; et al. The cloning of the human follicle stimulating hormone receptor and its expression in COS-7, CHO, and Y-1 cells. Mol. Cell. Endocrinol. 1993, 89 (1–2): 141–51. PMID 1301382. doi:10.1016/0303-7207(92)90220-Z. 引文格式1维护：显式使用等标签 (link)
Tilly JL, Aihara T, Nishimori K; et al. Expression of recombinant human follicle-stimulating hormone receptor: species-specific ligand binding, signal transduction, and identification of multiple ovarian messenger ribonucleic acid transcripts. Endocrinology. 1992, 131 (2): 799–806. PMID 1322283. doi:10.1210/en.131.2.799. 引文格式1维护：显式使用等标签 (link)
Gromoll J, Gudermann T, Nieschlag E. Molecular cloning of a truncated isoform of the human follicle stimulating hormone receptor. Biochem. Biophys. Res. Commun. 1992, 188 (3): 1077–83. PMID 1359889. doi:10.1016/0006-291X(92)91341-M.
Minegishi T, Nakamura K, Takakura Y; et al. Cloning and sequencing of human FSH receptor cDNA. Biochem. Biophys. Res. Commun. 1991, 175 (3): 1125–30. PMID 1709010. doi:10.1016/0006-291X(91)91682-3. 引文格式1维护：显式使用等标签 (link)
Gromoll J, Ried T, Holtgreve-Grez H; et al. Localization of the human FSH receptor to chromosome 2 p21 using a genomic probe comprising exon 10. J. Mol. Endocrinol. 1994, 12 (3): 265–71. PMID 7916967. doi:10.1677/jme.0.0120265. 引文格式1维护：显式使用等标签 (link)
Gromoll J, Dankbar B, Gudermann T. Characterization of the 5' flanking region of the human follicle-stimulating hormone receptor gene. Mol. Cell. Endocrinol. 1994, 102 (1–2): 93–102. PMID 7926278. doi:10.1016/0303-7207(94)90102-3.
Rousseau-Merck MF, Atger M, Loosfelt H; et al. The chromosomal localization of the human follicle-stimulating hormone receptor gene (FSHR) on 2p21-p16 is similar to that of the luteinizing hormone receptor gene. Genomics. 1993, 15 (1): 222–4. PMID 8432542. doi:10.1006/geno.1993.1041. 引文格式1维护：显式使用等标签 (link)
Jiang X, Dreano M, Buckler DR; et al. Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions. Structure. 1996, 3 (12): 1341–53. PMID 8747461. doi:10.1016/S0969-2126(01)00272-6. 引文格式1维护：显式使用等标签 (link)
Aittomäki K, Herva R, Stenman UH; et al. Clinical features of primary ovarian failure caused by a point mutation in the follicle-stimulating hormone receptor gene. J. Clin. Endocrinol. Metab. 1996, 81 (10): 3722–6. PMID 8855829. doi:10.1210/jc.81.10.3722. 引文格式1维护：显式使用等标签 (link)
Tapanainen JS, Aittomäki K, Min J; et al. Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nat. Genet. 1997, 15 (2): 205–6. PMID 9020851. doi:10.1038/ng0297-205. 引文格式1维护：显式使用等标签 (link)
Kotlar TJ, Young RH, Albanese C; et al. A mutation in the follicle-stimulating hormone receptor occurs frequently in human ovarian sex cord tumors. J. Clin. Endocrinol. Metab. 1997, 82 (4): 1020–6. PMID 9100567. doi:10.1210/jc.82.4.1020. 引文格式1维护：显式使用等标签 (link)
外部链接编辑
Glycoprotein Hormone Receptors: FSH. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. （原始内容于2014-04-07）.
十月 23, 2023
促卵泡激素受体, 英語, follicle, stimulating, hormone, receptor, receptor, fshr, 是一种在卵巢, 子宫和睾丸中发现的g蛋白偶联受体, gpcr, 其激活是在繁殖期间的荷尔蒙运作所需的, follicle, stimulating, hormone, receptorpdb, rendering, based, 4ay9, 有效结构pdb, 直系同源检索, pdbe, rcsbpdb查询代码列表1xwd, 4ay9标识代号fshr, fshro, lgr1,. 促卵泡激素受体 英語 follicle stimulating hormone receptor FSH receptor FSHR 是一种在卵巢 子宫和睾丸中发现的G蛋白偶联受体 GPCR 其激活是在繁殖期间的荷尔蒙运作所需的 Follicle stimulating hormone receptor促卵泡激素受体PDB rendering based on 4AY9 有效结构PDB 直系同源检索 PDBe RCSBPDB查询代码列表1XWD 4AY9标识代号FSHR FSHRO LGR1 ODG1扩展标识遗传学 136435 鼠基因 95583 同源基因 117 IUPHAR FSH ChEMBL 2024 GeneCards FSHR Gene基因本体论描述分子功能 follicle stimulating hormone receptor activity protein binding细胞成分 plasma membrane integral to membrane生物过程 G protein coupled receptor signaling pathway spermatogenesis female gamete generation gonad development male gonad development female gonad development follicle stimulating hormone signaling pathwaySources Amigo QuickGORNA表达模式更多表达数据直系同源体物种人类小鼠Entrez249214309EnsemblENSG00000170820ENSMUSG00000032937UniProtP23945P35378mRNA序列NM 000145NM 013523蛋白序列NP 000136NP 038551基因位置Chr 2 49 19 49 38 MbChr 17 88 99 89 2 MbPubMed查询 1 2 查论编 目录 1 FSHR基因 2 历史 3 另见 4 参考文献 5 延伸阅读 6 外部链接FSHR基因 编辑FSHR 基因位于人的2號染色體上p21区 长约2080个核苷酸 1 历史 编辑馬丁 羅德貝爾与艾爾佛列 古曼 吉爾曼因发现G蛋白系统而获得1994年的诺贝尔生理学或医学奖 另见 编辑黄体生成素 绒毛膜促性腺激素受体参考文献 编辑 Simoni M Gromoll J Nieschlag E The follicle stimulating hormone receptor biochemistry molecular biology physiology and pathophysiology Endocr Rev December 1997 18 6 739 73 PMID 9408742 doi 10 1210 er 18 6 739 延伸阅读 编辑de la Chapelle A Disease gene mapping in isolated human populations the example of Finland J Med Genet 1993 30 10 857 65 PMC 1016570 nbsp PMID 8230163 doi 10 1136 jmg 30 10 857 Amsterdam A Hanoch T Dantes A et al Mechanisms of gonadotropin desensitization Mol Cell Endocrinol 2003 187 1 2 69 74 PMID 11988313 doi 10 1016 S0303 7207 01 00701 8 引文格式1维护 显式使用等标签 link Simoni M Nieschlag E Gromoll J Isoforms and single nucleotide polymorphisms of the FSH receptor gene implications for human reproduction Hum Reprod Update 2003 8 5 413 21 PMID 12398222 doi 10 1093 humupd 8 5 413 Delbaere A Smits G Olatunbosun O et al New insights into the pathophysiology of ovarian hyperstimulation syndrome What makes the difference between spontaneous and iatrogenic syndrome Hum Reprod 2004 19 3 486 9 PMC 2891954 nbsp PMID 14998941 doi 10 1093 humrep deh124 引文格式1维护 显式使用等标签 link Bose CK Role of nerve growth factor and FSH receptor in epithelial ovarian cancer Reprod Biomed Online 2005 11 2 194 7 PMID 16168216 doi 10 1016 S1472 6483 10 60958 3 Wunsch A Sonntag B Simoni M Polymorphism of the FSH receptor and ovarian response to FSH Ann Endocrinol Paris 2007 68 2 3 160 6 PMID 17544358 doi 10 1016 j ando 2007 04 006 Kelton CA Cheng SV Nugent NP et al The cloning of the human follicle stimulating hormone receptor and its expression in COS 7 CHO and Y 1 cells Mol Cell Endocrinol 1993 89 1 2 141 51 PMID 1301382 doi 10 1016 0303 7207 92 90220 Z 引文格式1维护 显式使用等标签 link Tilly JL Aihara T Nishimori K et al Expression of recombinant human follicle stimulating hormone receptor species specific ligand binding signal transduction and identification of multiple ovarian messenger ribonucleic acid transcripts Endocrinology 1992 131 2 799 806 PMID 1322283 doi 10 1210 en 131 2 799 引文格式1维护 显式使用等标签 link Gromoll J Gudermann T Nieschlag E Molecular cloning of a truncated isoform of the human follicle stimulating hormone receptor Biochem Biophys Res Commun 1992 188 3 1077 83 PMID 1359889 doi 10 1016 0006 291X 92 91341 M Minegishi T Nakamura K Takakura Y et al Cloning and sequencing of human FSH receptor cDNA Biochem Biophys Res Commun 1991 175 3 1125 30 PMID 1709010 doi 10 1016 0006 291X 91 91682 3 引文格式1维护 显式使用等标签 link Gromoll J Ried T Holtgreve Grez H et al Localization of the human FSH receptor to chromosome 2 p21 using a genomic probe comprising exon 10 J Mol Endocrinol 1994 12 3 265 71 PMID 7916967 doi 10 1677 jme 0 0120265 引文格式1维护 显式使用等标签 link Gromoll J Dankbar B Gudermann T Characterization of the 5 flanking region of the human follicle stimulating hormone receptor gene Mol Cell Endocrinol 1994 102 1 2 93 102 PMID 7926278 doi 10 1016 0303 7207 94 90102 3 Rousseau Merck MF Atger M Loosfelt H et al The chromosomal localization of the human follicle stimulating hormone receptor gene FSHR on 2p21 p16 is similar to that of the luteinizing hormone receptor gene Genomics 1993 15 1 222 4 PMID 8432542 doi 10 1006 geno 1993 1041 引文格式1维护 显式使用等标签 link Jiang X Dreano M Buckler DR et al Structural predictions for the ligand binding region of glycoprotein hormone receptors and the nature of hormone receptor interactions Structure 1996 3 12 1341 53 PMID 8747461 doi 10 1016 S0969 2126 01 00272 6 引文格式1维护 显式使用等标签 link Aittomaki K Herva R Stenman UH et al Clinical features of primary ovarian failure caused by a point mutation in the follicle stimulating hormone receptor gene J Clin Endocrinol Metab 1996 81 10 3722 6 PMID 8855829 doi 10 1210 jc 81 10 3722 引文格式1维护 显式使用等标签 link Tapanainen JS Aittomaki K Min J et al Men homozygous for an inactivating mutation of the follicle stimulating hormone FSH receptor gene present variable suppression of spermatogenesis and fertility Nat Genet 1997 15 2 205 6 PMID 9020851 doi 10 1038 ng0297 205 引文格式1维护 显式使用等标签 link Kotlar TJ Young RH Albanese C et al A mutation in the follicle stimulating hormone receptor occurs frequently in human ovarian sex cord tumors J Clin Endocrinol Metab 1997 82 4 1020 6 PMID 9100567 doi 10 1210 jc 82 4 1020 引文格式1维护 显式使用等标签 link 外部链接 编辑Glycoprotein Hormone Receptors FSH IUPHAR Database of Receptors and Ion Channels International Union of Basic and Clinical Pharmacology 原始内容存档于2014 04 07 GRIS Glycoprotein hormone Receptor Information System 取自 https zh wikipedia org w index php title 促卵泡激素受体 amp oldid 68261584, 维基百科，wiki，书籍，书籍，图书馆，
