^Tata F, Henry I, Markham AF, Wallis SC, Weil D, Grzeschik KH, Junien C, Williamson R, Humphries SE. Isolation and characterisation of a cDNA clone for human apolipoprotein CI and assignment of the gene to chromosome 19. Hum. Genet. 1985, 69 (4): 345–9. PMID 2985493. doi:10.1007/BF00291654.
^Smit M, van der Kooij-Meijs E, Frants RR, Havekes L, Klasen EC. Apolipoprotein gene cluster on chromosome 19. Definite localization of the APOC2 gene and the polymorphic Hpa I site associated with type III hyperlipoproteinemia. Hum. Genet. January 1988, 78 (1): 90–3. PMID 2892779. doi:10.1007/BF00291243.
进一步阅读
Shulman RS, Herbert PN, Wehrly K, Fredrickson DS. Thf complete amino acid sequence of C-I (apoLp-Ser), an apolipoprotein from human very low density lipoproteins. J. Biol. Chem. 1975, 250 (1): 182–90. PMID 166984.
Lauer SJ, Walker D, Elshourbagy NA; et al. Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene. J. Biol. Chem. 1988, 263 (15): 7277–86. PMID 2835369. 引文格式1维护：显式使用等标签 (link)
Smit M, van der Kooij-Meijs E, Woudt LP; et al. Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene. Biochem. Biophys. Res. Commun. 1988, 152 (3): 1282–8. PMID 2897845. doi:10.1016/S0006-291X(88)80424-8. 引文格式1维护：显式使用等标签 (link)
Davison PJ, Norton P, Wallis SC; et al. There are two gene sequences for human apolipoprotein CI (apo CI) on chromosome 19, one of which is 4 kb from the gene for apo E. Biochem. Biophys. Res. Commun. 1986, 136 (3): 876–84. PMID 3013172. doi:10.1016/0006-291X(86)90414-6. 引文格式1维护：显式使用等标签 (link)
Myklebost O, Rogne S. The gene for human apolipoprotein CI is located 4.3 kilobases away from the apolipoprotein E gene on chromosome 19. Hum. Genet. 1986, 73 (4): 286–9. PMID 3017837. doi:10.1007/BF00279087.
Jackson RL, Sparrow JT, Baker HN; et al. The primary structure of apolopoprotein-serine. J. Biol. Chem. 1974, 249 (16): 5308–13. PMID 4369340. 引文格式1维护：显式使用等标签 (link)
Knott TJ, Robertson ME, Priestley LM; et al. Characterisation of mRNAs encoding the precursor for human apolipoprotein CI. Nucleic Acids Res. 1984, 12 (9): 3909–15. PMC 318798. PMID 6328444. doi:10.1093/nar/12.9.3909. 引文格式1维护：显式使用等标签 (link)
Servillo L, Brewer HB, Osborne JC. Evaluation of the mixed interaction between apolipoproteins A-II and C-I equilibrium sedimentation. Biophys. Chem. 1981, 13 (1): 29–38. PMID 6789904. doi:10.1016/0301-4622(81)80022-1.
Curry MD, McConathy WJ, Fesmire JD, Alaupovic P. Quantitative determination of apolipoproteins C-I and C-II in human plasma by separate electroimmunoassays. Clin. Chem. 1981, 27 (4): 543–8. PMID 7471419.
Rozek A, Buchko GW, Cushley RJ. Conformation of two peptides corresponding to human apolipoprotein C-I residues 7-24 and 35-53 in the presence of sodium dodecyl sulfate by CD and NMR spectroscopy. Biochemistry. 1995, 34 (22): 7401–8. PMID 7779782. doi:10.1021/bi00022a013.
Maruyama K, Sugano S. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene. 1994, 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8.
Trask B, Fertitta A, Christensen M; et al. Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers. Genomics. 1993, 15 (1): 133–45. PMID 8432525. doi:10.1006/geno.1993.1021. 引文格式1维护：显式使用等标签 (link)
Kamino K, Yoshiiwa A, Nishiwaki Y; et al. Genetic association study between senile dementia of Alzheimer's type and APOE/C1/C2 gene cluster. Gerontology. 1996,. 42 Suppl 1: 12–9. PMID 8804993. doi:10.1159/000213820. 引文格式1维护：显式使用等标签 (link)
Rozek A, Buchko GW, Kanda P, Cushley RJ. Conformational studies of the N-terminal lipid-associating domain of human apolipoprotein C-I by CD and 1H NMR spectroscopy. Protein Sci. 1998, 6 (9): 1858–68. PMC 2143781. PMID 9300485. doi:10.1002/pro.5560060906.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. Gene. 1997, 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3. 引文格式1维护：显式使用等标签 (link)
Halushka MK, Fan JB, Bentley K; et al. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat. Genet. 1999, 22 (3): 239–47. PMID 10391210. doi:10.1038/10297. 引文格式1维护：显式使用等标签 (link)
Freitas EM, Zhang WJ, Lalonde JP; et al. Sequencing of 42kb of the APO E-C2 gene cluster reveals a new gene: PEREC1. DNA Seq. 1999, 9 (2): 89–100. PMID 10520737. doi:10.3109/10425179809086433. 引文格式1维护：显式使用等标签 (link)
Gautier T, Masson D, de Barros JP; et al. Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity. J. Biol. Chem. 2001, 275 (48): 37504–9. PMID 10978346. doi:10.1074/jbc.M007210200. 引文格式1维护：显式使用等标签 (link)
Hartley JL, Temple GF, Brasch MA. DNA cloning using in vitro site-specific recombination. Genome Res. 2001, 10 (11): 1788–95. PMC 310948. PMID 11076863. doi:10.1101/gr.143000.
一月 27, 2023
载脂蛋白c1, 英語, apolipoprotein, 是一个由人类基因, apoc1, 编码的脂蛋白, apolipoprotein, ipdb, rendering, based, 1ioj, 有效结构pdb, 直系同源检索, pdbe, rcsbpdb查询代码列表1ale, 1alf, 1ioj, 1opp标识代号apoc1扩展标识遗传学, 107710, 鼠基因, 88053, 同源基因, 1244, genecards, apoc1, gene基因本体论描述分子功能, phospholipase, inh. 载脂蛋白C1 英語 Apolipoprotein C I 是一个由人类基因 APOC1 编码的脂蛋白 1 2 Apolipoprotein C I载脂蛋白C1PDB rendering based on 1ioj 有效结构PDB 直系同源检索 PDBe RCSBPDB查询代码列表1ALE 1ALF 1IOJ 1OPP标识代号APOC1扩展标识遗传学 107710 鼠基因 88053 同源基因 1244 GeneCards APOC1 Gene基因本体论描述分子功能 phospholipase inhibitor activity fatty acid binding phosphatidylcholine binding lipase inhibitor activity phosphatidylcholine sterol O acyltransferase activator activity细胞成分 endoplasmic reticulum very low density lipoprotein particle high density lipoprotein particle chylomicron生物过程 lipid metabolic process positive regulation of cholesterol esterification negative regulation of phosphatidylcholine catabolic process negative regulation of very low density lipoprotein particle clearance regulation of cholesterol transport negative regulation of cholesterol transport cholesterol efflux phospholipid efflux plasma lipoprotein particle remodeling high density lipoprotein particle remodeling very low density lipoprotein particle assembly chylomicron remnant clearance very low density lipoprotein particle clearance lipoprotein metabolic process negative regulation of fatty acid biosynthetic process negative regulation of lipid metabolic process negative regulation of receptor mediated endocytosis negative regulation of lipid catabolic process negative regulation of lipoprotein lipase activitySources Amigo QuickGO直系同源体物种人类小鼠Entrez34111812EnsemblENSG00000130208ENSMUSG00000040564UniProtP02654P34928mRNA序列NM 001645NM 001110009蛋白序列NP 001636NP 001103479基因位置Chr 19 45 42 45 42 MbChr 7 19 69 19 69 MbPubMed查询 1 2 查论编ApoC Istructural studies of a baboon papio sp plasma protein inhibitor of cholesteryl ester transferase 鑑定標誌ApoC IPfamPF04691InterPro 英语 InterPro IPR006781SCOP 英语 Structural Classification of Proteins 1ale SUPFAM現有可用的蛋白結構 Pfam結構 ECODPDBRCSB PDB PDBe PDBjPDBsum 英语 PDBsum 結構概要功能 编辑该基因编码的蛋白质是载脂蛋白C 英语 apolipoprotein C 家族中的一员 参考文献 编辑 Tata F Henry I Markham AF Wallis SC Weil D Grzeschik KH Junien C Williamson R Humphries SE Isolation and characterisation of a cDNA clone for human apolipoprotein CI and assignment of the gene to chromosome 19 Hum Genet 1985 69 4 345 9 PMID 2985493 doi 10 1007 BF00291654 Smit M van der Kooij Meijs E Frants RR Havekes L Klasen EC Apolipoprotein gene cluster on chromosome 19 Definite localization of the APOC2 gene and the polymorphic Hpa I site associated with type III hyperlipoproteinemia Hum Genet January 1988 78 1 90 3 PMID 2892779 doi 10 1007 BF00291243 进一步阅读 编辑Shulman RS Herbert PN Wehrly K Fredrickson DS Thf complete amino acid sequence of C I apoLp Ser an apolipoprotein from human very low density lipoproteins J Biol Chem 1975 250 1 182 90 PMID 166984 Lauer SJ Walker D Elshourbagy NA et al Two copies of the human apolipoprotein C I gene are linked closely to the apolipoprotein E gene J Biol Chem 1988 263 15 7277 86 PMID 2835369 引文格式1维护 显式使用等标签 link Smit M van der Kooij Meijs E Woudt LP et al Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene Biochem Biophys Res Commun 1988 152 3 1282 8 PMID 2897845 doi 10 1016 S0006 291X 88 80424 8 引文格式1维护 显式使用等标签 link Davison PJ Norton P Wallis SC et al There are two gene sequences for human apolipoprotein CI apo CI on chromosome 19 one of which is 4 kb from the gene for apo E Biochem Biophys Res Commun 1986 136 3 876 84 PMID 3013172 doi 10 1016 0006 291X 86 90414 6 引文格式1维护 显式使用等标签 link Myklebost O Rogne S The gene for human apolipoprotein CI is located 4 3 kilobases away from the apolipoprotein E gene on chromosome 19 Hum Genet 1986 73 4 286 9 PMID 3017837 doi 10 1007 BF00279087 Jackson RL Sparrow JT Baker HN et al The primary structure of apolopoprotein serine J Biol Chem 1974 249 16 5308 13 PMID 4369340 引文格式1维护 显式使用等标签 link Knott TJ Robertson ME Priestley LM et al Characterisation of mRNAs encoding the precursor for human apolipoprotein CI Nucleic Acids Res 1984 12 9 3909 15 PMC 318798 PMID 6328444 doi 10 1093 nar 12 9 3909 引文格式1维护 显式使用等标签 link Servillo L Brewer HB Osborne JC Evaluation of the mixed interaction between apolipoproteins A II and C I equilibrium sedimentation Biophys Chem 1981 13 1 29 38 PMID 6789904 doi 10 1016 0301 4622 81 80022 1 Curry MD McConathy WJ Fesmire JD Alaupovic P Quantitative determination of apolipoproteins C I and C II in human plasma by separate electroimmunoassays Clin Chem 1981 27 4 543 8 PMID 7471419 Rozek A Buchko GW Cushley RJ Conformation of two peptides corresponding to human apolipoprotein C I residues 7 24 and 35 53 in the presence of sodium dodecyl sulfate by CD and NMR spectroscopy Biochemistry 1995 34 22 7401 8 PMID 7779782 doi 10 1021 bi00022a013 Maruyama K Sugano S Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides Gene 1994 138 1 2 171 4 PMID 8125298 doi 10 1016 0378 1119 94 90802 8 Trask B Fertitta A Christensen M et al Fluorescence in situ hybridization mapping of human chromosome 19 cytogenetic band location of 540 cosmids and 70 genes or DNA markers Genomics 1993 15 1 133 45 PMID 8432525 doi 10 1006 geno 1993 1021 引文格式1维护 显式使用等标签 link Kamino K Yoshiiwa A Nishiwaki Y et al Genetic association study between senile dementia of Alzheimer s type and APOE C1 C2 gene cluster Gerontology 1996 42 Suppl 1 12 9 PMID 8804993 doi 10 1159 000213820 引文格式1维护 显式使用等标签 link Rozek A Buchko GW Kanda P Cushley RJ Conformational studies of the N terminal lipid associating domain of human apolipoprotein C I by CD and 1H NMR spectroscopy Protein Sci 1998 6 9 1858 68 PMC 2143781 PMID 9300485 doi 10 1002 pro 5560060906 Suzuki Y Yoshitomo Nakagawa K Maruyama K et al Construction and characterization of a full length enriched and a 5 end enriched cDNA library Gene 1997 200 1 2 149 56 PMID 9373149 doi 10 1016 S0378 1119 97 00411 3 引文格式1维护 显式使用等标签 link Halushka MK Fan JB Bentley K et al Patterns of single nucleotide polymorphisms in candidate genes for blood pressure homeostasis Nat Genet 1999 22 3 239 47 PMID 10391210 doi 10 1038 10297 引文格式1维护 显式使用等标签 link Freitas EM Zhang WJ Lalonde JP et al Sequencing of 42kb of the APO E C2 gene cluster reveals a new gene PEREC1 DNA Seq 1999 9 2 89 100 PMID 10520737 doi 10 3109 10425179809086433 引文格式1维护 显式使用等标签 link Gautier T Masson D de Barros JP et al Human apolipoprotein C I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity J Biol Chem 2001 275 48 37504 9 PMID 10978346 doi 10 1074 jbc M007210200 引文格式1维护 显式使用等标签 link Hartley JL Temple GF Brasch MA DNA cloning using in vitro site specific recombination Genome Res 2001 10 11 1788 95 PMC 310948 PMID 11076863 doi 10 1101 gr 143000 取自 https zh wikipedia org w index php title 载脂蛋白C1 amp oldid 67768660, 维基百科，wiki，书籍，书籍，图书馆，
