^Neville, GA.; Beckstead, HD.; Shurvell, HF. A Fourier transform-Raman and infrared vibrational study of delorazepam, fludiazepam, flurazepam, and tetrazepam.. J Pharm Sci. Feb 1994, 83 (2): 143–51. PMID 7909552. doi:10.1002/jps.2600830207.
^Su, TP.; Chen, TJ.; Hwang, SJ.; Chou, LF.; Fan, AP.; Chen, YC. Utilization of psychotropic drugs in Taiwan: an overview of outpatient sector in 2000.. Zhonghua Yi Xue Za Zhi (Taipei). Aug 2002, 65 (8): 378–91. PMID 12455808.
^Tsuchiya, T.; Fukushima, H. Effects of benzodiazepines and pentobarbitone on the gaba-ergic recurrent inhibition of hippocampal neurons.. Eur J Pharmacol. Apr 1978, 48 (4): 421–4. PMID 648585. doi:10.1016/0014-2999(78)90169-3.
^Nakatsuka, I.; Shimizu, H.; Asami, Y.; Katoh, T.; Hirose, A.; Yoshitake, A. Benzodiazepines and their metabolites: relationship between binding affinity to the benzodiazepine receptor and pharmacological activity.. Life Sci. Jan 1985, 36 (2): 113–9. PMID 2857046. doi:10.1016/0024-3205(85)90089-X.
^Okada, S.; Ichiki, K.; Tanokuchi, S.; Ishii, K.; Hamada, H.; Ota, Z. Effect of an anxiolytic on lipid profile in non-insulin-dependent diabetes mellitus.. J Int Med Res. 1994, 22 (6): 338–42. PMID 7895897.
^Okada, S.; Ichiki, K.; Tanokuchi, S.; Ishii, K.; Hamada, H.; Ota, Z. Improvement of stress reduces glycosylated haemoglobin levels in patients with type 2 diabetes.. J Int Med Res. 1995, 23 (2): 119–22. PMID 7601294.
^Okada, S.; Ichiki, K.; Tanokuchi, S.; Ishii, K.; Hamada, H.; Ota, Z. How blood pressure in patients with non-insulin-dependent diabetes mellitus is influenced by stress.. J Int Med Res. 1995, 23 (5): 377–80. PMID 8529781.
^Inoue, H.; Maeno, Y.; Iwasa, M.; Matoba, R.; Nagao, M. Screening and determination of benzodiazepines in whole blood using solid-phase extraction and gas chromatography/mass spectrometry.. Forensic Sci Int. Sep 2000, 113 (1-3): 367–73. PMID 10978650. doi:10.1016/S0379-0738(00)00226-7.
^Shimamine, M.; Masunari, T.; Nakahara, Y. [Studies on identification of drugs of abuse by diode array detection. I. Screening-test and identification of benzodiazepines by HPLC-DAD with ICOS software system]. Eisei Shikenjo Hokoku. 1993, (111): 47–56. PMID 7920567.
（日語） Erispan フルジアゼパム錠，細粒[永久失效連結] (PDF) Dainippon Sumitomo Pharma. November 2005.
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一月 01, 2023
氟地西泮, 提示, 此条目的主题不是指氟硝西泮, 俗稱fm2, 维基百科中的醫學内容仅供参考, 並不能視作專業意見, 如需獲取醫療幫助或意見, 请咨询专业人士, 詳見醫學聲明, fludiazepam, 是由羅氏藥廠, hoffman, laroche, 在20世紀60年代所開發的一種苯二氮平類藥物之衍生藥物, 和地西泮有密切關聯, 在日本商品名, erispan, 在台灣商品名, 癒利舒盼錠, erispan, 福安源錠, flupine, 用0, 25毫克的片劑裝來銷售, 臨床資料ahfs, 英语, ameri. 提示 此条目的主题不是指氟硝西泮 俗稱FM2 维基百科中的醫學内容仅供参考 並不能視作專業意見 如需獲取醫療幫助或意見 请咨询专业人士 詳見醫學聲明 氟地西泮 Fludiazepam 是由羅氏藥廠 Hoffman LaRoche 在20世紀60年代所開發的一種苯二氮平類藥物之衍生藥物 和地西泮有密切關聯 1 2 在日本商品名 Erispan 在台灣商品名 癒利舒盼錠 Erispan 福安源錠 Flupine 用0 25毫克的片劑裝來銷售 3 4 氟地西泮臨床資料AHFS 英语 American Society of Health System Pharmacists Drugs com国际药品名称懷孕分級 给药途径OralATC碼N05BA17 WHO 法律規範狀態法律規範加 Schedule IV 德 Anlage III 美 Schedule IV 臺 第四級管制藥品 Schedule IV US 藥物動力學數據生物利用度 药物代谢肝臟生物半衰期 排泄途徑腎识别信息IUPAC命名法 7 chloro 5 2 fluorophenyl 1 methyl 1H benzo e 1 4 diazepin 2 3H oneCAS号3900 31 0 PubChem CID3369DrugBankDB01567 ChemSpider3252 UNII7F64A2K16ZKEGGD01354 ChEBICHEBI 31618 ChEMBLChEMBL13291 CompTox Dashboard EPA DTXSID00192277ECHA InfoCard100 292 343化学信息化学式C 16H 12Cl F N 2O摩尔质量302 73D模型 JSmol 交互式图像SMILES O C1CN C C2 CC CC C2F C3 CC Cl CC C3N1CInChI InChI 1S C16H12ClFN2O c1 20 14 7 6 10 17 8 12 14 16 19 9 15 20 21 11 4 2 3 5 13 11 18 h2 8H 9H2 1H3 Key ROYOYTLGDLIGBX UHFFFAOYSA N 氟地西泮通過增強GABA的抑制性來發揮其藥理特性 5 且氟地西泮對苯二氮卓受體 benzodiazepine receptor 比起對地西泮來有四倍多的結合親和力 6 它具有抗焦慮 7 8 9 抗驚厥 鎮靜 催眠及骨骼肌鬆弛等特性 10 不過 氟地西泮有藥物濫用的潛在趨勢 11 在多個國家列為管制藥品 註釋 编辑 US Patent 3299053 ARYL JH L X BENZODIAZEPIN Z LH ONES Neville GA Beckstead HD Shurvell HF A Fourier transform Raman and infrared vibrational study of delorazepam fludiazepam flurazepam and tetrazepam J Pharm Sci Feb 1994 83 2 143 51 PMID 7909552 doi 10 1002 jps 2600830207 Su TP Chen TJ Hwang SJ Chou LF Fan AP Chen YC Utilization of psychotropic drugs in Taiwan an overview of outpatient sector in 2000 Zhonghua Yi Xue Za Zhi Taipei Aug 2002 65 8 378 91 PMID 12455808 Benzodiazepine Names non benzodiazepines org uk 2008 12 29 原始内容存档于2008 12 08 Tsuchiya T Fukushima H Effects of benzodiazepines and pentobarbitone on the gaba ergic recurrent inhibition of hippocampal neurons Eur J Pharmacol Apr 1978 48 4 421 4 PMID 648585 doi 10 1016 0014 2999 78 90169 3 Nakatsuka I Shimizu H Asami Y Katoh T Hirose A Yoshitake A Benzodiazepines and their metabolites relationship between binding affinity to the benzodiazepine receptor and pharmacological activity Life Sci Jan 1985 36 2 113 9 PMID 2857046 doi 10 1016 0024 3205 85 90089 X Okada S Ichiki K Tanokuchi S Ishii K Hamada H Ota Z Effect of an anxiolytic on lipid profile in non insulin dependent diabetes mellitus J Int Med Res 1994 22 6 338 42 PMID 7895897 Okada S Ichiki K Tanokuchi S Ishii K Hamada H Ota Z Improvement of stress reduces glycosylated haemoglobin levels in patients with type 2 diabetes J Int Med Res 1995 23 2 119 22 PMID 7601294 Okada S Ichiki K Tanokuchi S Ishii K Hamada H Ota Z How blood pressure in patients with non insulin dependent diabetes mellitus is influenced by stress J Int Med Res 1995 23 5 377 80 PMID 8529781 Inoue H Maeno Y Iwasa M Matoba R Nagao M Screening and determination of benzodiazepines in whole blood using solid phase extraction and gas chromatography mass spectrometry Forensic Sci Int Sep 2000 113 1 3 367 73 PMID 10978650 doi 10 1016 S0379 0738 00 00226 7 Shimamine M Masunari T Nakahara Y Studies on identification of drugs of abuse by diode array detection I Screening test and identification of benzodiazepines by HPLC DAD with ICOS software system Eisei Shikenjo Hokoku 1993 111 47 56 PMID 7920567 參見 编辑苯二氮平類藥物外部連結 编辑 日語 Erispan フルジアゼパム錠 細粒 永久失效連結 PDF Dainippon Sumitomo Pharma November 2005 日語 Official Dainippon Sumitomo Pharma Website 页面存档备份 存于互联网档案馆 取自 https zh wikipedia org w index php title 氟地西泮 amp oldid 68712294, 维基百科，wiki，书籍，书籍，图书馆，
