鳞状细胞癌抗原-1（英語：Squamous cell carcinoma antigen-1，缩写SCCA-1、SCCA1，也称为肿瘤相关抗TA4、丝氨酸蛋白酶抑制剂家族B亚家族成员3，serpin family B member 3，缩写SERPINB3）是一个人类18号染色体上的基因，编码一种丝氨酸蛋白酶抑制剂蛋白，是鳞状细胞癌的肿瘤标志物[5][6]。
^ 1.01.11.2GRCh38: Ensembl release 89: ENSG00000057149 - Ensembl, May 2017
^ 2.02.12.2GRCm38: Ensembl release 89: ENSMUSG00000058017 - Ensembl, May 2017
^Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci U S A. May 1995, 92 (8): 3147–51. Bibcode:1995PNAS...92.3147S. PMC 42122. PMID 7724531. doi:10.1073/pnas.92.8.3147.
^Entrez Gene: SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3.
外部链接编辑
The MEROPS online database for peptidases and their inhibitors: I04.008
鳞状细胞癌抗原, 英語, squamous, cell, carcinoma, antigen, 缩写scca, scca1, 也称为肿瘤相关抗ta4, 丝氨酸蛋白酶抑制剂家族b亚家族成员3, serpin, family, member, 缩写serpinb3, 是一个人类18号染色体上的基因, 编码一种丝氨酸蛋白酶抑制剂蛋白, 是鳞状细胞癌的肿瘤标志物, 已知的結構pdb直系同源搜索, pdbe, rcsbpdbid列表2zv6, 4zk0, 4zk3識別號别名serpinb3, hst1196, scca, . 鳞状细胞癌抗原 1 英語 Squamous cell carcinoma antigen 1 缩写SCCA 1 SCCA1 也称为肿瘤相关抗TA4 丝氨酸蛋白酶抑制剂家族B亚家族成员3 serpin family B member 3 缩写SERPINB3 是一个人类18号染色体上的基因 编码一种丝氨酸蛋白酶抑制剂蛋白 是鳞状细胞癌的肿瘤标志物 5 6 鳞状细胞癌抗原 1已知的結構PDB直系同源搜索 PDBe RCSBPDBID列表2ZV6 4ZK0 4ZK3識別號别名SERPINB3 HsT1196 SCC SCCA 1 SCCA PD SCCA1 T4 A SSCA1 serpin family B member 3外部IDOMIM 600517 MGI 2683295 HomoloGene 130559 GeneCards SERPINB3基因位置 人类 染色体18號染色體 1 基因座18q21 33起始63 655 197 bp 1 终止63 661 893 bp 1 基因位置 小鼠 染色体小鼠1号染色体 2 基因座1 E2 1 1起始107 005 897 bp 2 终止107 011 236 bp 2 RNA表达模式查阅更多表达数据基因本體分子功能 virus receptor activity 蛋白酶結合 cysteine type endopeptidase inhibitor activity peptidase inhibitor activity serine type endopeptidase inhibitor activity細胞組分 细胞核 囊泡 cytoplasmic vesicle 外排體 細胞質 細胞外區域 細胞外空間 azurophil granule lumen生物學過程 旁分泌 positive regulation of cell population proliferation 自分泌 negative regulation of catalytic activity negative regulation of JUN kinase activity positive regulation of endopeptidase activity positive regulation of epithelial to mesenchymal transition negative regulation of proteolysis negative regulation of endopeptidase activity positive regulation of cell migration 病毒进入 negative regulation of peptidase activity neutrophil degranulationSources Amigo QuickGO直系同源物種人類小鼠Entrez6317394252EnsemblENSG00000057149ENSMUSG00000058017UniProtP29508Q6UKZ0mRNA 序列NM 006919NM 201376蛋白序列NP 008850NP 958764基因位置 UCSC Chr 18 63 66 63 66 MbChr 1 107 01 107 01 MbPubMed 查找 3 4 維基數據檢視 編輯人類檢視 編輯小鼠参考文献 编辑 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000057149 Ensembl May 2017 2 0 2 1 2 2 GRCm38 Ensembl release 89 ENSMUSG00000058017 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Schneider SS Schick C Fish KE Miller E Pena JC Treter SD Hui SM Silverman GA A serine proteinase inhibitor locus at 18q21 3 contains a tandem duplication of the human squamous cell carcinoma antigen gene Proc Natl Acad Sci U S A May 1995 92 8 3147 51 Bibcode 1995PNAS 92 3147S PMC 42122 nbsp PMID 7724531 doi 10 1073 pnas 92 8 3147 nbsp Entrez Gene SERPINB3 serpin peptidase inhibitor clade B ovalbumin member 3 外部链接 编辑The MEROPS online database for peptidases and their inhibitors I04 008 醫學主題詞表 MeSH SERPINB3 protein human 取自 https zh wikipedia org w index php title 鳞状细胞癌抗原 1 amp oldid 76741704, 维基百科，wiki，书籍，书籍，图书馆，
