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Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.. Gene. 1997, 200 (1-2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3. 引文格式1维护：显式使用等标签 (link)
Lai CH, Chou CY, Ch'ang LY; et al. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.. Genome Res. 2000, 10 (5): 703–13. PMC 310876. PMID 10810093. doi:10.1101/gr.10.5.703. 引文格式1维护：显式使用等标签 (link)
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Kharroubi I, Rasschaert J, Eizirik DL, Cnop M. Expression of adiponectin receptors in pancreatic beta cells.. Biochem. Biophys. Res. Commun. 2004, 312 (4): 1118–22. PMID 14651988. doi:10.1016/j.bbrc.2003.11.042.
Ota T, Suzuki Y, Nishikawa T; et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.. Nat. Genet. 2004, 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285. 引文格式1维护：显式使用等标签 (link)
Civitarese AE, Jenkinson CP, Richardson D; et al. Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes.. Diabetologia. 2005, 47 (5): 816–20. PMID 15105989. doi:10.1007/s00125-004-1359-x. 引文格式1维护：显式使用等标签 (link)
Wang H, Zhang H, Jia Y; et al. Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance.. Diabetes. 2004, 53 (8): 2132–6. PMID 15277397. doi:10.2337/diabetes.53.8.2132. 引文格式1维护：显式使用等标签 (link)
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Jonsson JR, Moschen AR, Hickman IJ; et al. Adiponectin and its receptors in patients with chronic hepatitis C.. J. Hepatol. 2006, 43 (6): 929–36. PMID 16139921. doi:10.1016/j.jhep.2005.05.030. 引文格式1维护：显式使用等标签 (link)
一月 27, 2023
脂联素受体1, 英語, adiponectin, receptor, 缩写adipor1, 是一种由人类基因, adipor1, 编码的蛋白质, adiponectin, receptor, 1标识代号adipor1, acdcr1, cgi45, paqr1, tesbp1a扩展标识遗传学, 607945, 鼠基因, 1919924, 同源基因, 69199, iuphar, genecards, adipor1, gene基因本体论描述分子功能, receptor, activity, protein, kin. 脂联素受体1 英語 Adiponectin receptor 1 缩写ADIPOR1 是一种由人类基因 ADIPOR1 编码的蛋白质 1 Adiponectin receptor 1脂联素受体1标识代号ADIPOR1 ACDCR1 CGI45 PAQR1 TESBP1A扩展标识遗传学 607945 鼠基因 1919924 同源基因 69199 IUPHAR GeneCards ADIPOR1 Gene基因本体论描述分子功能 receptor activity protein kinase binding hormone binding identical protein binding protein heterodimerization activity细胞成分 plasma membrane membrane integral component of membrane生物过程 hormone mediated signaling pathway fatty acid oxidation negative regulation of cell growth leptin mediated signaling pathway adiponectin activated signaling pathway positive regulation of JAK STAT cascade positive regulation of insulin receptor signaling pathwaySources Amigo QuickGORNA表达模式更多表达数据直系同源体物种人类小鼠Entrez5109472674EnsemblENSG00000159346ENSMUSG00000026457UniProtQ96A54Q91VH1mRNA序列NM 001290553NM 028320蛋白序列NP 001277482NP 082596基因位置Chr 1 202 91 202 93 MbChr 1 134 42 134 43 MbPubMed查询 1 2 查论编 目录 1 结构 2 功能 3 参考文献 4 延伸阅读结构 编辑ADIPOR1和G蛋白偶联受体 GPCRs 类似 都拥有7个跨膜结构域 英语 transmembrane domain 但是ADIPOR1的七跨膜的位置与GPCRs相反 N 端在细胞内 C 端在细胞外 也不能与G蛋白相互作用 1 功能 编辑脂联素的受体 ADIPOR1和ADIPOR2 能应答球状或全长的脂联素信号 促使AMPK 英语 AMP activated protein kinase 和PPAR a 英语 Peroxisome proliferator activated receptor alpha 配体活性增加 以及脂肪酸的氧化和葡萄糖摄取 1 2 参考文献 编辑 1 0 1 1 1 2 Yamauchi T Kamon J Ito Y Tsuchida A Yokomizo T Kita S Sugiyama T Miyagishi M Hara K Tsunoda M Murakami K Ohteki T Uchida S Takekawa S Waki H Tsuno NH Shibata Y Terauchi Y Froguel P Tobe K Koyasu S Taira K Kitamura T Shimizu T Nagai R Kadowaki T Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature June 2003 423 6941 762 9 PMID 12802337 doi 10 1038 nature01705 Entrez Gene ADIPOR1 adiponectin receptor 1 延伸阅读 编辑Crimmins NA Martin LJ Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance Obesity reviews an official journal of the International Association for the Study of Obesity 2007 8 5 419 23 PMID 17716299 doi 10 1111 j 1467 789X 2007 00348 x Maruyama K Sugano S Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides Gene 1994 138 1 2 171 4 PMID 8125298 doi 10 1016 0378 1119 94 90802 8 Suzuki Y Yoshitomo Nakagawa K Maruyama K et al Construction and characterization of a full length enriched and a 5 end enriched cDNA library Gene 1997 200 1 2 149 56 PMID 9373149 doi 10 1016 S0378 1119 97 00411 3 引文格式1维护 显式使用等标签 link Lai CH Chou CY Ch ang LY et al Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics Genome Res 2000 10 5 703 13 PMC 310876 PMID 10810093 doi 10 1101 gr 10 5 703 引文格式1维护 显式使用等标签 link Strausberg RL Feingold EA Grouse LH et al Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 2003 99 26 16899 903 PMC 139241 PMID 12477932 doi 10 1073 pnas 242603899 引文格式1维护 显式使用等标签 link Yamauchi T Kamon J Ito Y et al Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 2003 423 6941 762 9 PMID 12802337 doi 10 1038 nature01705 引文格式1维护 显式使用等标签 link Kharroubi I Rasschaert J Eizirik DL Cnop M Expression of adiponectin receptors in pancreatic beta cells Biochem Biophys Res Commun 2004 312 4 1118 22 PMID 14651988 doi 10 1016 j bbrc 2003 11 042 Ota T Suzuki Y Nishikawa T et al Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 2004 36 1 40 5 PMID 14702039 doi 10 1038 ng1285 引文格式1维护 显式使用等标签 link Civitarese AE Jenkinson CP Richardson D et al Adiponectin receptors gene expression and insulin sensitivity in non diabetic Mexican Americans with or without a family history of Type 2 diabetes Diabetologia 2005 47 5 816 20 PMID 15105989 doi 10 1007 s00125 004 1359 x 引文格式1维护 显式使用等标签 link Wang H Zhang H Jia Y et al Adiponectin receptor 1 gene ADIPOR1 as a candidate for type 2 diabetes and insulin resistance Diabetes 2004 53 8 2132 6 PMID 15277397 doi 10 2337 diabetes 53 8 2132 引文格式1维护 显式使用等标签 link Staiger H Kaltenbach S Staiger K et al Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism Diabetes 2004 53 9 2195 201 PMID 15331527 doi 10 2337 diabetes 53 9 2195 引文格式1维护 显式使用等标签 link Berner HS Lyngstadaas SP Spahr A et al Adiponectin and its receptors are expressed in bone forming cells Bone 2005 35 4 842 9 PMID 15454091 doi 10 1016 j bone 2004 06 008 引文格式1维护 显式使用等标签 link Gerhard DS Wagner L Feingold EA et al The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 2004 14 10B 2121 7 PMC 528928 PMID 15489334 doi 10 1101 gr 2596504 引文格式1维护 显式使用等标签 link Punyadeera C Zorenc AH Koopman R et al The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle Eur J Endocrinol 2005 152 3 427 36 PMID 15757860 doi 10 1530 eje 1 01872 引文格式1维护 显式使用等标签 link Hara K Horikoshi M Kitazato H et al Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes Diabetologia 2005 48 7 1307 14 PMID 15918014 doi 10 1007 s00125 005 1806 3 引文格式1维护 显式使用等标签 link Damcott CM Ott SH Pollin TI et al Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish Diabetes 2005 54 7 2245 50 PMID 15983228 doi 10 2337 diabetes 54 7 2245 引文格式1维护 显式使用等标签 link Neumeier M Weigert J Schaffler A et al Regulation of adiponectin receptor 1 in human hepatocytes by agonists of nuclear receptors Biochem Biophys Res Commun 2006 334 3 924 9 PMID 16023994 doi 10 1016 j bbrc 2005 06 187 引文格式1维护 显式使用等标签 link Zhang J Holt H Wang C et al Expression of AdipoR1 in vivo in skeletal muscle is independently associated with measures of truncal obesity in middle aged caucasian men Diabetes Care 2005 28 8 2058 60 PMID 16043761 doi 10 2337 diacare 28 8 2058 引文格式1维护 显式使用等标签 link Tang YT Hu T Arterburn M et al PAQR proteins a novel membrane receptor family defined by an ancient 7 transmembrane pass motif J Mol Evol 2005 61 3 372 80 PMID 16044242 doi 10 1007 s00239 004 0375 2 引文格式1维护 显式使用等标签 link Jonsson JR Moschen AR Hickman IJ et al Adiponectin and its receptors in patients with chronic hepatitis C J Hepatol 2006 43 6 929 36 PMID 16139921 doi 10 1016 j jhep 2005 05 030 引文格式1维护 显式使用等标签 link 取自 https zh wikipedia org w index php title 脂联素受体1 amp oldid 69143255, 维基百科，wiki，书籍，书籍，图书馆，
