甘露聚糖结合凝集素 （英語：Mannose-binding lectin ，縮寫MBL ，也被称为甘露糖结合蛋白 或甘露聚糖结合蛋白 ，英語：mannan-binding protein ，縮寫MBP ）是一種在先天免疫系統 中起作用的凝集素 [1] [2]
Mannose-binding lectin (protein C) 2, soluble PDB rendering based on 1hup.
有效结构 PDB 直系同源检索：PDBe, RCSB
标识 代号 MBL2; COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD 扩展标识 遗传学 ：154545 鼠基因 ：96924 同源基因 ：110436 ChEMBL : 1795113 GeneCards : MBL2 Gene 基因本体论描述 分子功能 · receptor binding · protein binding · mannose binding · eukaryotic cell surface binding · calcium-dependent protein binding
· bacterial cell surface binding 细胞成分 · extracellular region · collagen
· extracellular space 生物过程 · complement activation, lectin pathway · acute-phase response · complement activation · complement activation, classical pathway · response to oxidative stress · opsonization · negative regulation of growth of symbiont in host · innate immune response · positive regulation of phagocytosis · defense response to Gram-positive bacterium
· killing by host of symbiont cells Sources: Amigo / QuickGO
RNA表达模式 更多表达数据 直系同源体 物种 人类 小鼠 Entrez 4153 17195 Ensembl ENSG00000165471 ENSMUSG00000024863 UniProt P11226 P41317 mRNA序列 NM_000242 NM_010776 蛋白序列 NP_000233 NP_034906 基因位置 Chr 10: Chr 19: PubMed 查询 [1] [2]
外部連接 编辑 参考文獻 编辑 ^ Fraser IP, Koziel H, Ezekowitz RA. The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity.. Semin. Immunol. 1998, 10 (5): 363–72. PMID 9799711 . doi:10.1006/smim.1998.0141 . ^ Worthley DL, Bardy PG, Mullighan CG. Mannose-binding lectin: biology and clinical implications.. Internal medicine journal. 2005, 35 (9): 548–55. PMID 16105157 . doi:10.1111/j.1445-5994.2005.00908.x .
甘露聚糖结合凝集素, 英語, mannose, binding, lectin, 縮寫mbl, 也被称为甘露糖结合蛋白或甘露聚糖结合蛋白, 英語, mannan, binding, protein, 縮寫mbp, 是一種在先天免疫系統中起作用的凝集素, mannose, binding, lectin, protein, soluble甘露糖结合凝集素, 蛋白c, 可溶pdb, rendering, based, 1hup, 有效结构pdb, 直系同源检索, pdbe, rcsbpdb查询代码列表1hup标识代号m. 甘露聚糖结合凝集素 英語 Mannose binding lectin 縮寫MBL 也被称为甘露糖结合蛋白或甘露聚糖结合蛋白 英語 mannan binding protein 縮寫MBP 是一種在先天免疫系統中起作用的凝集素 1 2 Mannose binding lectin protein C 2 soluble甘露糖结合凝集素 蛋白C 2 可溶PDB rendering based on 1hup 有效结构PDB 直系同源检索 PDBe RCSBPDB查询代码列表1HUP标识代号MBL2 COLEC1 HSMBPC MBL MBL2D MBP MBP C MBP1 MBPD扩展标识遗传学 154545 鼠基因 96924 同源基因 110436 ChEMBL 1795113 GeneCards MBL2 Gene基因本体论描述分子功能 receptor binding protein binding mannose binding eukaryotic cell surface binding calcium dependent protein binding bacterial cell surface binding细胞成分 extracellular region collagen extracellular space生物过程 complement activation lectin pathway acute phase response complement activation complement activation classical pathway response to oxidative stress opsonization negative regulation of growth of symbiont in host innate immune response positive regulation of phagocytosis defense response to Gram positive bacterium killing by host of symbiont cellsSources Amigo QuickGORNA表达模式更多表达数据直系同源体物种人类小鼠Entrez415317195EnsemblENSG00000165471ENSMUSG00000024863UniProtP11226P41317mRNA序列NM 000242NM 010776蛋白序列NP 000233NP 034906基因位置Chr 10 54 53 54 53 MbChr 19 30 23 30 24 MbPubMed查询 1 2 查论编外部連接 编辑醫學主題詞表 MeSH Mannan Binding Lectin参考文獻 编辑 Fraser IP Koziel H Ezekowitz RA The serum mannose binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity Semin Immunol 1998 10 5 363 72 PMID 9799711 doi 10 1006 smim 1998 0141 Worthley DL Bardy PG Mullighan CG Mannose binding lectin biology and clinical implications Internal medicine journal 2005 35 9 548 55 PMID 16105157 doi 10 1111 j 1445 5994 2005 00908 x 取自 https zh wikipedia org w index php title 甘露聚糖结合凝集素 amp oldid 69140355, 维基百科，wiki ，书籍，书籍，图书馆，
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