· extrinsic component of endoplasmic reticulum membrane
生物过程
· response to hypoxia
· regulation of protein phosphorylation · positive regulation of defense response to virus by host · transcription, DNA-templated · regulation of transcription, DNA-templated · protein complex assembly · protein targeting · apoptotic process · activation of cysteine-type endopeptidase activity involved in apoptotic process · DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest · cell cycle arrest · transforming growth factor beta receptor signaling pathway · common-partner SMAD protein phosphorylation · SMAD protein import into nucleus · negative regulation of cell proliferation · intrinsic apoptotic signaling pathway in response to DNA damage · intrinsic apoptotic signaling pathway in response to oxidative stress · response to UV · response to gamma radiation · regulation of calcium ion transport into cytosol · viral process · negative regulation of angiogenesis · cytokine-mediated signaling pathway · myeloid cell differentiation · negative regulation of cell growth · PML body organization · positive regulation of histone deacetylation · negative regulation of telomere maintenance via telomerase · endoplasmic reticulum calcium ion homeostasis · circadian regulation of gene expression · negative regulation of translation in response to oxidative stress · response to cytokine · regulation of circadian rhythm · intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator · entrainment of circadian clock by photoperiod · proteasome-mediated ubiquitin-dependent protein catabolic process · innate immune response · cell fate commitment · regulation of MHC class I biosynthetic process · negative regulation of transcription, DNA-templated · negative regulation of mitotic cell cycle · retinoic acid receptor signaling pathway · protein stabilization · maintenance of protein location in nucleus · defense response to virus · negative regulation of telomerase activity · positive regulation of apoptotic process involved in mammary gland involution · interferon-gamma-mediated signaling pathway · branching involved in mammary gland duct morphogenesis · intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress · cellular response to interleukin-4 · cellular senescence · extrinsic apoptotic signaling pathway · negative regulation of viral release from host cell · negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process · regulation of double-strand break repair
· positive regulation of extrinsic apoptotic signaling pathway
^Doucas, Vassilis; Tini, Marc; Egan, David A.; Evans, Ronald M. . Proceedings of the National Academy of Sciences. 1999-03-16, 96 (6) [2022-06-16]. ISSN 0027-8424. PMC 15819. PMID 10077561. doi:10.1073/pnas.96.6.2627. （原始内容存档于2022-06-16） （英语）.
^Marcello, A. Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein. The EMBO Journal. 2003-05-01, 22 (9). PMC 156077. PMID 12727882. doi:10.1093/emboj/cdg205.
^Ishov, Alexander M.; Sotnikov, Alexey G.; Negorev, Dmitri; Vladimirova, Olga V.; Neff, Norma; Kamitani, Tetsu; Yeh, Edward T.H.; Strauss, Jerome F.; Maul, Gerd G. . Journal of Cell Biology. 1999-10-18, 147 (2) [2022-06-16]. ISSN 0021-9525. PMC 2174231. PMID 10525530. doi:10.1083/jcb.147.2.221. （原始内容存档于2022-06-16） （英语）.
^Hong, Suk-Hyun; Yang, Zhihong; Privalsky, Martin L. . Molecular and Cellular Biology. 2001-11, 21 (21) [2022-06-16]. ISSN 0270-7306. PMC 99892. PMID 11585900. doi:10.1128/MCB.21.21.7172-7182.2001. （原始内容存档于2021-08-11） （英语）.
^Fogal, V. Regulation of p53 activity in nuclear bodies by a specific PML isoform. The EMBO Journal. 2000-11-15, 19 (22). PMC 305840. PMID 11080164. doi:10.1093/emboj/19.22.6185.
^Xu, Zhi-Xiang; Timanova-Atanasova, Anna; Zhao, Rui-Xun; Chang, Kun-Sang. PML Colocalizes with and Stabilizes the DNA Damage Response Protein TopBP1. Molecular and Cellular Biology. 2003-06-15, 23 (12). ISSN 0270-7306. PMC 156140. PMID 12773567. doi:10.1128/MCB.23.12.4247-4256.2003（英语）.
^Takahashi, Hidehisa; Hatakeyama, Shigetsugu; Saitoh, Hisato; Nakayama, Keiichi I. . The Journal of Biological Chemistry. 2005-02-18, 280 (7) [2022-06-16]. ISSN 0021-9258. PMID 15569683. doi:10.1074/jbc.M408130200. （原始内容存档于2022-06-16）.
^Koken, M. H. M.; Reid, A.; Quignon, F.; Chelbi-Alix, M. K.; Davies, J. M.; Kabarowski, J. H. S.; Zhu, J.; Dong, S.; Chen, S.-J.; Chen, Z.; Tan, C. C. . Proceedings of the National Academy of Sciences. 1997-09-16, 94 (19) [2022-06-16]. ISSN 0027-8424. PMC 23349. PMID 9294197. doi:10.1073/pnas.94.19.10255. （原始内容存档于2022-06-16） （英语）.
早幼粒细胞白血病蛋白, 是指可能的转录因子可能的转录因子, 英語, probable, transcription, factor, 是一个由人类基因, 编码的抑癌蛋白, promyelocytic, leukemiapdb, rendering, based, 1bor, 有效结构pdb, 直系同源检索, pdbe, rcsbpdb查询代码列表1bor标识代号pml, pp8675, rnf71, trim19扩展标识遗传学, 102578, 鼠基因, 104662, 同源基因, 13245, genecards. 早幼粒细胞白血病蛋白是指可能的转录因子可能的转录因子 英語 Probable transcription factor PML 是一个由人类基因 PML 编码的抑癌蛋白 Promyelocytic leukemia早幼粒细胞白血病蛋白PDB rendering based on 1bor 有效结构PDB 直系同源检索 PDBe RCSBPDB查询代码列表1BOR标识代号PML MYL PP8675 RNF71 TRIM19扩展标识遗传学 102578 鼠基因 104662 同源基因 13245 GeneCards PML Gene基因本体论描述分子功能 DNA binding transcription coactivator activity protein binding zinc ion binding ubiquitin protein ligase binding SUMO binding protein homodimerization activity SMAD binding protein heterodimerization activity cobalt ion binding细胞成分 nucleus nucleoplasm nucleolus cytoplasm cytosol nuclear matrix PML body early endosome membrane nuclear membrane extrinsic component of endoplasmic reticulum membrane生物过程 response to hypoxia regulation of protein phosphorylation positive regulation of defense response to virus by host transcription DNA templated regulation of transcription DNA templated protein complex assembly protein targeting apoptotic process activation of cysteine type endopeptidase activity involved in apoptotic process DNA damage response signal transduction by p53 class mediator resulting in cell cycle arrest cell cycle arrest transforming growth factor beta receptor signaling pathway common partner SMAD protein phosphorylation SMAD protein import into nucleus negative regulation of cell proliferation intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress response to UV response to gamma radiation regulation of calcium ion transport into cytosol viral process negative regulation of angiogenesis cytokine mediated signaling pathway myeloid cell differentiation negative regulation of cell growth PML body organization positive regulation of histone deacetylation negative regulation of telomere maintenance via telomerase endoplasmic reticulum calcium ion homeostasis circadian regulation of gene expression negative regulation of translation in response to oxidative stress response to cytokine regulation of circadian rhythm intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator entrainment of circadian clock by photoperiod proteasome mediated ubiquitin dependent protein catabolic process innate immune response cell fate commitment regulation of MHC class I biosynthetic process negative regulation of transcription DNA templated negative regulation of mitotic cell cycle retinoic acid receptor signaling pathway protein stabilization maintenance of protein location in nucleus defense response to virus negative regulation of telomerase activity positive regulation of apoptotic process involved in mammary gland involution interferon gamma mediated signaling pathway branching involved in mammary gland duct morphogenesis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to interleukin 4 cellular senescence extrinsic apoptotic signaling pathway negative regulation of viral release from host cell negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process regulation of double strand break repair positive regulation of extrinsic apoptotic signaling pathwaySources Amigo QuickGO直系同源体物种人类小鼠Entrez537118854EnsemblENSG00000140464ENSMUSG00000036986UniProtP29590Q60953mRNA序列NM 002675NM 008884蛋白序列NP 002666NP 032910基因位置Chr 15 74 29 74 34 MbChr 9 58 22 58 25 MbPubMed查询 1 2 查论编 目录 1 功能 2 互作 3 参见 4 参考文献 5 延伸阅读 6 外部链接功能 编辑互作 编辑早幼粒细胞白血病蛋白可与下列蛋白質发生交互作用 ANKRD2 1 CREB binding protein 2 3 4 Cyclin T1 5 Death associated protein 6 6 7 8 9 GATA2 10 HDAC1 11 12 HDAC3 12 HHEX 13 MAPK11 14 MYB 15 Mdm2 16 17 18 19 Nerve Growth factor IB 20 Nuclear receptor co repressor 1 11 Nuclear receptor co repressor 2 11 21 P53 16 22 23 RPL11 17 视网膜母细胞瘤蛋白 24 视黄酸受体a 2 SIN3A 11 SKI protein 11 STAT3 25 Serum response factor 3 and Small ubiquitin related modifier 1 26 27 Sp1 transcription factor 28 TOPBP1 29 Thymine DNA glycosylase 30 and Zinc finger and BTB domain containing protein 16 31 参见 编辑RING finger domain参考文献 编辑 Kojic Snezana Medeot Elisa Guccione Ernesto Krmac Helena Zara Ivano Martinelli Valentina Valle Giorgio Faulkner Georgine The Ankrd2 Protein a Link Between the Sarcomere and the Nucleus in Skeletal Muscle Journal of Molecular Biology 2004 05 339 2 2022 06 16 doi 10 1016 j jmb 2004 03 071 原始内容存档于2022 06 15 英语 2 0 2 1 Zhong Sue Delva Laurent Rachez Christophe Cenciarelli Cristina Gandini Domenica Zhang Hui Kalantry Sundeep Freedman Leonard P Pandolfi Pier Paolo A RA dependent tumour growth suppressive transcription complex is the target of the PML RARa and T18 oncoproteins Nature Genetics 1999 11 23 3 2022 06 16 ISSN 1061 4036 PMID 10610177 doi 10 1038 15463 原始内容存档于2022 03 10 英语 3 0 3 1 Matsuzaki Kazuhito Minami Takeshi Tojo Masahide Honda Yoshiomi Saitoh Noriko Nagahiro Shinji Saya Hideyuki Nakao Mitsuyoshi PML nuclear bodies are involved in cellular serum response Genes to Cells Devoted to Molecular amp Cellular Mechanisms 2003 03 8 3 2022 06 16 ISSN 1356 9597 PMID 12622724 doi 10 1046 j 1365 2443 2003 00632 x 原始内容存档于2022 06 16 Doucas Vassilis Tini Marc Egan David A Evans Ronald M Modulation of CREB binding protein function by the promyelocytic PML oncoprotein suggests a role for nuclear bodies in hormone signaling Proceedings of the National Academy of Sciences 1999 03 16 96 6 2022 06 16 ISSN 0027 8424 PMC 15819 nbsp PMID 10077561 doi 10 1073 pnas 96 6 2627 原始内容存档于2022 06 16 英语 Marcello A Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein The EMBO Journal 2003 05 01 22 9 PMC 156077 nbsp PMID 12727882 doi 10 1093 emboj cdg205 Ishov Alexander M Sotnikov Alexey G Negorev Dmitri Vladimirova Olga V Neff Norma Kamitani Tetsu Yeh Edward T H Strauss Jerome F Maul Gerd G Pml Is Critical for Nd10 Formation and Recruits the Pml Interacting Protein Daxx to This Nuclear Structure When Modified by Sumo 1 Journal of Cell Biology 1999 10 18 147 2 2022 06 16 ISSN 0021 9525 PMC 2174231 nbsp PMID 10525530 doi 10 1083 jcb 147 2 221 原始内容存档于2022 06 16 英语 Li Hui Leo Christopher Zhu Jiang Wu Xiaoyang O Neil Jennifer Park Eun Ju Chen J Don Sequestration and Inhibition of Daxx Mediated Transcriptional Repression by PML Molecular and Cellular Biology 2000 03 20 5 2022 06 16 ISSN 0270 7306 PMC 85360 nbsp PMID 10669754 doi 10 1128 MCB 20 5 1784 1796 2000 原始内容存档于2021 11 28 英语 Lehembre Francois Muller Stefan Pandolfi Pier Paolo Dejean Anne Regulation of Pax3 transcriptional activity by SUMO 1 modified PML Oncogene 2001 01 04 20 1 2022 06 16 ISSN 0950 9232 PMID 11244500 doi 10 1038 sj onc 1204063 原始内容存档于2021 08 11 英语 Zhong Sue Salomoni Paolo Ronchetti Simona Guo Ailan Ruggero Davide Pandolfi Pier Paolo Promyelocytic Leukemia Protein Pml and Daxx Participate in a Novel Nuclear Pathway for Apoptosis Journal of Experimental Medicine 2000 02 21 191 4 2022 06 16 ISSN 0022 1007 PMC 2195846 nbsp PMID 10684855 doi 10 1084 jem 191 4 631 原始内容存档于2022 06 16 英语 Tsuzuki Shinobu Towatari Masayuki Saito Hidehiko Enver Tariq Potentiation of GATA 2 Activity through Interactions with the Promyelocytic Leukemia Protein PML and the t 15 17 Generated PML Retinoic Acid Receptor a Oncoprotein Molecular and Cellular Biology 2000 09 20 17 2022 06 16 ISSN 0270 7306 PMC 86102 nbsp PMID 10938104 doi 10 1128 MCB 20 17 6276 6286 2000 原始内容存档于2022 06 16 英语 11 0 11 1 11 2 11 3 11 4 Khan M M Nomura T Kim H Kaul S C Wadhwa R Shinagawa T Ichikawa Iwata E Zhong S Pandolfi P P Ishii S Role of PML and PML RARalpha in Mad mediated transcriptional repression Molecular Cell 2001 06 7 6 2022 06 16 ISSN 1097 2765 PMID 11430826 doi 10 1016 s1097 2765 01 00257 x 原始内容存档于2021 11 28 12 0 12 1 Wu Wen Shu Vallian Sadeq Seto Edward Yang Wen Ming Edmondson Diane Roth Sharon Chang Kun Sang The Growth Suppressor PML Represses Transcription by Functionally and Physically Interacting with Histone Deacetylases Molecular and Cellular Biology 2001 04 21 7 2022 06 16 ISSN 0270 7306 PMC 86860 nbsp PMID 11259576 doi 10 1128 MCB 21 7 2259 2268 2001 原始内容存档于2022 06 16 英语 Topcu Zeki Mack David L Hromas Robert A Borden Katherine LB The promyelocytic leukemia protein PML interacts with the proline rich homeodomain protein PRH a RING may link hematopoiesis and growth control Oncogene 1999 11 25 18 50 2022 06 16 ISSN 0950 9232 PMID 10597310 doi 10 1038 sj onc 1203201 原始内容存档于2022 06 16 英语 Shin Jinwook Park Boyoun Cho Sunglim Lee Sunray Kim Youngkyun Lee Seong Ok Cho Kwangmin Lee Sungwook Jin Bong Suk Ahn Jin Hyun Choi Eui Ju Promyelocytic leukemia is a direct inhibitor of SAPK2 p38 mitogen activated protein kinase The Journal of Biological Chemistry 2004 09 24 279 39 2022 06 16 ISSN 0021 9258 PMID 15273249 doi 10 1074 jbc M407369200 原始内容存档于2022 06 16 Dahle Oyvind Bakke Oddmund Gabrielsen Odd Stokke c Myb associates with PML in nuclear bodies in hematopoietic cells Experimental Cell Research 2004 07 01 297 1 2022 06 16 ISSN 0014 4827 PMID 15194430 doi 10 1016 j yexcr 2004 03 014 原始内容存档于2022 06 16 16 0 16 1 Kurki Sari Latonen Leena Laiho Marikki Cellular stress and DNA damage invoke temporally distinct Mdm2 p53 and PML complexes and damage specific nuclear relocalization Journal of Cell Science 2003 10 01 116 19 2022 06 16 ISSN 1477 9137 PMID 12915590 doi 10 1242 jcs 00714 原始内容存档于2022 06 16 英语 17 0 17 1 Bernardi Rosa Scaglioni Pier Paolo Bergmann Stephan Horn Henning F Vousden Karen H Pandolfi Pier Paolo PML regulates p53 stability by sequestering Mdm2 to the nucleolus Nature Cell Biology 2004 07 6 7 2022 06 16 ISSN 1465 7392 PMID 15195100 doi 10 1038 ncb1147 原始内容存档于2022 06 17 英语 Zhu Hongyan Wu Liqing Maki Carl G MDM2 and promyelocytic leukemia antagonize each other through their direct interaction with p53 The Journal of Biological Chemistry 2003 12 05 278 49 2022 06 16 ISSN 0021 9258 PMID 14507915 doi 10 1074 jbc M308302200 原始内容存档于2022 06 16 Wei Xiaolong Yu Zhong Kang Ramalingam Arivudainambi Grossman Steven R Yu Jiang H Bloch Donald B Maki Carl G Physical and functional interactions between PML and MDM2 The Journal of Biological Chemistry 2003 08 01 278 31 2022 06 16 ISSN 0021 9258 PMID 12759344 doi 10 1074 jbc M212215200 原始内容存档于2022 06 16 Wu Wen Shu Xu Zhi Xiang Ran Ruixiang Meng Feng Chang Kun Sang Promyelocytic leukemia protein PML inhibits Nur77 mediated transcription through specific functional interactions Oncogene 2002 05 30 21 24 2022 06 16 ISSN 0950 9232 PMID 12032831 doi 10 1038 sj onc 1205491 原始内容存档于2022 06 16 英语 Hong Suk Hyun Yang Zhihong Privalsky Martin L Arsenic Trioxide Is a Potent Inhibitor of the Interaction of SMRT Corepressor with Its Transcription Factor Partners Including the PML Retinoic Acid Receptor a Oncoprotein Found in Human Acute Promyelocytic Leukemia Molecular and Cellular Biology 2001 11 21 21 2022 06 16 ISSN 0270 7306 PMC 99892 nbsp PMID 11585900 doi 10 1128 MCB 21 21 7172 7182 2001 原始内容存档于2021 08 11 英语 Fogal V Regulation of p53 activity in nuclear bodies by a specific PML isoform The EMBO Journal 2000 11 15 19 22 PMC 305840 nbsp PMID 11080164 doi 10 1093 emboj 19 22 6185 Guo Ailan Salomoni Paolo Luo Jianyuan Shih Alan Zhong Sue Gu Wei Paolo Pandolfi Pier The function of PML in p53 dependent apoptosis Nature Cell Biology 2000 10 2 10 2022 06 16 ISSN 1465 7392 PMID 11025664 doi 10 1038 35036365 原始内容存档于2022 06 16 英语 Alcalay Myriam Tomassoni Lucia Colombo Emanuela Stoldt Stephan Grignani Francesco Fagioli Marta Szekely Laszlo Helin Kristian Pelicci Pier Giuseppe The Promyelocytic Leukemia Gene Product PML Forms Stable Complexes with the Retinoblastoma Protein Molecular and Cellular Biology 1998 02 18 2 2022 06 16 ISSN 0270 7306 PMC 108821 nbsp PMID 9448006 doi 10 1128 MCB 18 2 1084 原始内容存档于2022 06 16 英语 Kawasaki Akira Matsumura Itaru Kataoka Yoshihisa Takigawa Eri Nakajima Koichi Kanakura Yuzuru Opposing effects of PML and PML RARa on STAT3 activity Blood 2003 05 01 101 9 2022 06 16 ISSN 1528 0020 PMID 12506013 doi 10 1182 blood 2002 08 2474 原始内容存档于2022 06 16 英语 Lin Ding Yen Shih Hsiu Ming Essential role of the 58 kDa microspherule protein in the modulation of Daxx dependent transcriptional repression as revealed by nucleolar sequestration The Journal of Biological Chemistry 2002 07 12 277 28 2022 06 16 ISSN 0021 9258 PMID 11948183 doi 10 1074 jbc M200633200 原始内容存档于2022 06 20 Kamitani T Nguyen H P Kito K Fukuda Kamitani T Yeh E T Covalent modification of PML by the sentrin family of ubiquitin like proteins The Journal of Biological Chemistry 1998 02 06 273 6 2022 06 16 ISSN 0021 9258 PMID 9452416 doi 10 1074 jbc 273 6 3117 原始内容存档于2022 06 20 Vallian Sadeq Chin Khew Voon Chang Kun Sang The Promyelocytic Leukemia Protein Interacts with Sp1 and Inhibits Its Transactivation of the Epidermal Growth Factor Receptor Promoter Molecular and Cellular Biology 1998 12 18 12 2022 06 16 ISSN 0270 7306 PMC 109296 nbsp PMID 9819401 doi 10 1128 MCB 18 12 7147 原始内容存档于2022 06 16 英语 Xu Zhi Xiang Timanova Atanasova Anna Zhao Rui Xun Chang Kun Sang PML Colocalizes with and Stabilizes the DNA Damage Response Protein TopBP1 Molecular and Cellular Biology 2003 06 15 23 12 ISSN 0270 7306 PMC 156140 nbsp PMID 12773567 doi 10 1128 MCB 23 12 4247 4256 2003 英语 Takahashi Hidehisa Hatakeyama Shigetsugu Saitoh Hisato Nakayama Keiichi I Noncovalent SUMO 1 binding activity of thymine DNA glycosylase TDG is required for its SUMO 1 modification and colocalization with the promyelocytic leukemia protein The Journal of Biological Chemistry 2005 02 18 280 7 2022 06 16 ISSN 0021 9258 PMID 15569683 doi 10 1074 jbc M408130200 原始内容存档于2022 06 16 Koken M H M Reid A Quignon F Chelbi Alix M K Davies J M Kabarowski J H S Zhu J Dong S Chen S J Chen Z Tan C C Leukemia associated retinoic acid receptor a fusion partners PML and PLZF heterodimerize and colocalize to nuclear bodies Proceedings of the National Academy of Sciences 1997 09 16 94 19 2022 06 16 ISSN 0027 8424 PMC 23349 nbsp PMID 9294197 doi 10 1073 pnas 94 19 10255 原始内容存档于2022 06 16 英语 延伸阅读 编辑Zhong Sue Salomoni Paolo Pandolfi Pier Paolo The transcriptional role of PML and the nuclear body Nature Cell Biology 2000 05 2 5 2022 06 16 ISSN 1465 7392 PMID 10806494 doi 10 1038 35010583 原始内容存档于2022 03 10 英语 Jensen Kirsten Shiels Carol Freemont Paul S PML protein isoforms and the RBCC TRIM motif Oncogene 2001 10 29 20 49 2022 06 16 ISSN 0950 9232 PMID 11704850 doi 10 1038 sj onc 1204765 原始内容存档于2022 05 25 英语 Pearson Mark Pelicci Pier Giuseppe PML interaction with p53 and its role in apoptosis and replicative senescence Oncogene 2001 10 29 20 49 2022 06 16 ISSN 0950 9232 PMID 11704853 doi 10 1038 sj onc 1204856 原始内容存档于2022 06 16 英语 gt Salomoni Paolo Pandolfi Pier Paolo The role of PML in tumor suppression Cell 2002 01 25 108 2 2022 06 16 ISSN 0092 8674 PMID 11832207 doi 10 1016 s0092 8674 02 00626 8 原始内容存档于2022 03 02 Combes Robert Balls Michael Bansil Lee Barratt Martin Bell David Botham Phil Broadhead Caren Clothier Richard George Elizabeth Fentem Julia Jackson Michael An Assessment of Progress in the Use of Alternatives in Toxicity Testing since the Publication of the Report of the Second FRAME Toxicity Committee 1991 Alternatives to Laboratory Animals 2002 07 30 4 2022 06 16 ISSN 0261 1929 PMID 12234245 doi 10 1177 026119290203000403 原始内容存档于2021 08 10 英语 Bernardi Rosa Pandolfi Pier Paolo Role of PML and the PML nuclear body in the control of programmed cell death Oncogene 2003 12 08 22 56 2022 06 16 ISSN 0950 9232 PMID 14663483 doi 10 1038 sj onc 1207106 原始内容存档于2022 06 16 英语 Beez Sabine Demmer Philipp Puccetti Elena Tse William 编 Targeting the Acute Promyelocytic Leukemia Associated Fusion Proteins PML RARa and PLZF RARa with Interfering Peptides PLoS ONE 2012 11 09 7 11 ISSN 1932 6203 PMC 3494703 nbsp PMID 23152790 doi 10 1371 journal pone 0048636 英语 外部链接 编辑醫學主題詞表 MeSH PML protein human 取自 https zh wikipedia org w index php title 早幼粒细胞白血病蛋白 amp oldid 79719007, 维基百科，wiki，书籍，书籍，图书馆，
