^Sairam MR, Li CH. Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit. Biochim Biophys Acta. Feb 1976, 412 (1): 70–81. PMID 1191677.
^Sherman GB, Wolfe MW, Farmerie TA, Clay CM, Threadgill DS, Sharp DC, Nilson JH. A single gene encodes the beta-subunits of equine luteinizing hormone and chorionic gonadotropin. Mol. Endocrinol. June 1992, 6 (6): 951–9. PMID 1379674. doi:10.1210/me.6.6.951.
延伸阅读编辑
Keutmann HT, Hua QX, Weiss MA. Structure of a receptor-binding fragment from human luteinizing hormone beta-subunit determined by [1H]- and [15N]nuclear magnetic resonance spectroscopy. Mol. Endocrinol. 1992, 6 (6): 904–13. PMID 1495492. doi:10.1210/me.6.6.904.
Weiss J, Axelrod L, Whitcomb RW; et al. Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone. N. Engl. J. Med. 1992, 326 (3): 179–83. PMID 1727547. doi:10.1056/NEJM199201163260306. 引文格式1维护：显式使用等标签 (link)
Weisshaar G, Hiyama J, Renwick AG, Nimtz M. NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin. Eur. J. Biochem. 1991, 195 (1): 257–68. PMID 1991473. doi:10.1111/j.1432-1033.1991.tb15702.x.
Jameson JL, Lindell CM, Habener JF. Evolution of different transcriptional start sites in the human luteinizing hormone and chorionic gonadotropin beta-subunit genes. DNA. 1986, 5 (3): 227–34. PMID 2424697. doi:10.1089/dna.1986.5.227.
Keutmann HT, Charlesworth MC, Mason KA; et al. A receptor-binding region in human choriogonadotropin/lutropin beta subunit. Proc. Natl. Acad. Sci. U.S.A. 1987, 84 (7): 2038–42. PMC 304579. PMID 3470775. doi:10.1073/pnas.84.7.2038. 引文格式1维护：显式使用等标签 (link)
Shome B, Parlow AF. The primary structure of the hormone-specific, beta subunit of human pituitary luteinizing hormone (hLH). J. Clin. Endocrinol. Metab. 1973, 36 (3): 618–21. PMID 4685398. doi:10.1210/jcem-36-3-618.
Closset J, Hennen G, Lequin RM. Human luteinizing hormone. The amino acid sequence of the subunit. FEBS Lett. 1973, 29 (2): 97–100. PMID 4719207. doi:10.1016/0014-5793(73)80534-4.
Talmadge K, Vamvakopoulos NC, Fiddes JC. Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone. Nature. 1984, 307 (5946): 37–40. PMID 6690982. doi:10.1038/307037a0.
Beitins IZ, Axelrod L, Ostrea T; et al. Hypogonadism in a male with an immunologically active, biologically inactive luteinizing hormone: characterization of the abnormal hormone. J. Clin. Endocrinol. Metab. 1981, 52 (6): 1143–9. PMID 6785294. doi:10.1210/jcem-52-6-1143. 引文格式1维护：显式使用等标签 (link)
Berger P, Kranewitter W, Madersbacher S; et al. Eutopic production of human chorionic gonadotropin beta (hCG beta) and luteinizing hormone beta (hLH beta) in the human testis. FEBS Lett. 1994, 343 (3): 229–33. PMID 7513655. doi:10.1016/0014-5793(94)80561-X. 引文格式1维护：显式使用等标签 (link)
Keutmann HT, Rubin DA. A subunit interaction site in human luteinizing hormone: identification by photoaffinity cross-linking. Endocrinology. 1993, 132 (3): 1305–12. PMID 7679977. doi:10.1210/en.132.3.1305.
Herrlich A, Kühn B, Grosse R; et al. Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C. J. Biol. Chem. 1996, 271 (28): 16764–72. PMID 8663226. doi:10.1074/jbc.271.28.16764. 引文格式1维护：显式使用等标签 (link)
Muyan M, Furuhashi M, Sugahara T, Boime I. The carboxy-terminal region of the beta-subunits of luteinizing hormone and chorionic gonadotropin differentially influence secretion and assembly of the heterodimers. Mol. Endocrinol. 1997, 10 (12): 1678–87. PMID 8961276. doi:10.1210/me.10.12.1678.
Roy AC, Liao WX, Chen Y; et al. Identification of seven novel mutations in LH beta-subunit gene by SSCP. Mol. Cell. Biochem. 1997, 165 (2): 151–3. PMID 8979264. 引文格式1维护：显式使用等标签 (link)
Liao WX, Roy AC, Chan C; et al. A new molecular variant of luteinizing hormone associated with female infertility. Fertil. Steril. 1998, 69 (1): 102–6. PMID 9457942. doi:10.1016/S0015-0282(97)00445-7. 引文格式1维护：显式使用等标签 (link)
O'Connor JF, Kovalevskaya G, Birken S; et al. The expression of the urinary forms of human luteinizing hormone beta fragment in various populations as assessed by a specific immunoradiometric assay. Hum. Reprod. 1998, 13 (4): 826–35. PMID 9619532. doi:10.1093/humrep/13.4.826. 引文格式1维护：显式使用等标签 (link)
Takahashi K, Kurioka H, Ozaki T; et al. Increased prevalence of luteinizing hormone beta-subunit variant in Japanese infertility patients. Hum. Reprod. 1999, 13 (12): 3338–44. PMID 9886510. doi:10.1093/humrep/13.12.3338. 引文格式1维护：显式使用等标签 (link)
Elter K, Erel CT, Cine N; et al. Role of the mutations Trp8 => Arg and Ile15 => Thr of the human luteinizing hormone beta-subunit in women with polycystic ovary syndrome. Fertil. Steril. 1999, 71 (3): 425–30. PMID 10065776. doi:10.1016/S0015-0282(98)00491-9. 引文格式1维护：显式使用等标签 (link)
Jiang M, Pakarinen P, Zhang FP; et al. A common polymorphic allele of the human luteinizing hormone beta-subunit gene: additional mutations and differential function of the promoter sequence. Hum. Mol. Genet. 1999, 8 (11): 2037–46. PMID 10484773. doi:10.1093/hmg/8.11.2037. 引文格式1维护：显式使用等标签 (link)
十月 21, 2023
黄体生成素β亚基, 英語, luteinizing, hormone, subunit, beta, lutropin, subunit, beta, 是一种由人类基因lhb, 编码的蛋白质, luteinizing, hormone, beta, polypeptide黄体生成素β多肽有效结构pdb, 直系同源检索, pdbe, rcsbpdb查询代码列表1m92标识代号lhb, cgb4, hlhb扩展标识遗传学, 152780, 鼠基因, 96782, 同源基因, 81806, genecards, gene. 黄体生成素b亚基 英語 Luteinizing hormone subunit beta 或 lutropin subunit beta 是一种由人类基因LHB 编码的蛋白质 1 2 Luteinizing hormone beta polypeptide黄体生成素b多肽有效结构PDB 直系同源检索 PDBe RCSBPDB查询代码列表1M92标识代号LHB CGB4 LSH B hLHB扩展标识遗传学 152780 鼠基因 96782 同源基因 81806 GeneCards LHB Gene基因本体论描述分子功能 receptor binding hormone activity细胞成分 extracellular region生物过程 progesterone biosynthetic process signal transduction cell cell signaling male gonad development peptide hormone processing cellular protein metabolic processSources Amigo QuickGORNA表达模式更多表达数据直系同源体物种人类小鼠Entrez397216866EnsemblENSG00000104826ENSMUSG00000038194UniProtP01229G3X9G6mRNA序列NM 000894NM 008497蛋白序列NP 000885NP 032523基因位置Chr 19 49 52 49 52 MbChr 7 45 42 45 42 MbPubMed查询 1 2 查论编 目录 1 基因 2 功能 3 临床意义 4 参考文献 5 延伸阅读基因 编辑该基因位于19号染色体q13 3 编码黄体生成素的b亚基 2 而在马科动物中 黄体生成素的b亚基和绒毛膜促性腺激素的b亚基是由一个基因编码的 3 功能 编辑临床意义 编辑参考文献 编辑 Sairam MR Li CH Human pituitary lutropin Isolation properties and the complete amino acid sequence of the beta subunit Biochim Biophys Acta Feb 1976 412 1 70 81 PMID 1191677 2 0 2 1 Entrez Gene LHB luteinizing hormone beta polypeptide Sherman GB Wolfe MW Farmerie TA Clay CM Threadgill DS Sharp DC Nilson JH A single gene encodes the beta subunits of equine luteinizing hormone and chorionic gonadotropin Mol Endocrinol June 1992 6 6 951 9 PMID 1379674 doi 10 1210 me 6 6 951 延伸阅读 编辑Keutmann HT Hua QX Weiss MA Structure of a receptor binding fragment from human luteinizing hormone beta subunit determined by 1H and 15N nuclear magnetic resonance spectroscopy Mol Endocrinol 1992 6 6 904 13 PMID 1495492 doi 10 1210 me 6 6 904 Weiss J Axelrod L Whitcomb RW et al Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone N Engl J Med 1992 326 3 179 83 PMID 1727547 doi 10 1056 NEJM199201163260306 引文格式1维护 显式使用等标签 link Weisshaar G Hiyama J Renwick AG Nimtz M NMR investigations of the N linked oligosaccharides at individual glycosylation sites of human lutropin Eur J Biochem 1991 195 1 257 68 PMID 1991473 doi 10 1111 j 1432 1033 1991 tb15702 x Jameson JL Lindell CM Habener JF Evolution of different transcriptional start sites in the human luteinizing hormone and chorionic gonadotropin beta subunit genes DNA 1986 5 3 227 34 PMID 2424697 doi 10 1089 dna 1986 5 227 Keutmann HT Charlesworth MC Mason KA et al A receptor binding region in human choriogonadotropin lutropin beta subunit Proc Natl Acad Sci U S A 1987 84 7 2038 42 PMC 304579 nbsp PMID 3470775 doi 10 1073 pnas 84 7 2038 引文格式1维护 显式使用等标签 link Shome B Parlow AF The primary structure of the hormone specific beta subunit of human pituitary luteinizing hormone hLH J Clin Endocrinol Metab 1973 36 3 618 21 PMID 4685398 doi 10 1210 jcem 36 3 618 Closset J Hennen G Lequin RM Human luteinizing hormone The amino acid sequence of the subunit FEBS Lett 1973 29 2 97 100 PMID 4719207 doi 10 1016 0014 5793 73 80534 4 Talmadge K Vamvakopoulos NC Fiddes JC Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone Nature 1984 307 5946 37 40 PMID 6690982 doi 10 1038 307037a0 Beitins IZ Axelrod L Ostrea T et al Hypogonadism in a male with an immunologically active biologically inactive luteinizing hormone characterization of the abnormal hormone J Clin Endocrinol Metab 1981 52 6 1143 9 PMID 6785294 doi 10 1210 jcem 52 6 1143 引文格式1维护 显式使用等标签 link Berger P Kranewitter W Madersbacher S et al Eutopic production of human chorionic gonadotropin beta hCG beta and luteinizing hormone beta hLH beta in the human testis FEBS Lett 1994 343 3 229 33 PMID 7513655 doi 10 1016 0014 5793 94 80561 X 引文格式1维护 显式使用等标签 link Keutmann HT Rubin DA A subunit interaction site in human luteinizing hormone identification by photoaffinity cross linking Endocrinology 1993 132 3 1305 12 PMID 7679977 doi 10 1210 en 132 3 1305 Herrlich A Kuhn B Grosse R et al Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C J Biol Chem 1996 271 28 16764 72 PMID 8663226 doi 10 1074 jbc 271 28 16764 引文格式1维护 显式使用等标签 link Muyan M Furuhashi M Sugahara T Boime I The carboxy terminal region of the beta subunits of luteinizing hormone and chorionic gonadotropin differentially influence secretion and assembly of the heterodimers Mol Endocrinol 1997 10 12 1678 87 PMID 8961276 doi 10 1210 me 10 12 1678 Roy AC Liao WX Chen Y et al Identification of seven novel mutations in LH beta subunit gene by SSCP Mol Cell Biochem 1997 165 2 151 3 PMID 8979264 引文格式1维护 显式使用等标签 link Liao WX Roy AC Chan C et al A new molecular variant of luteinizing hormone associated with female infertility Fertil Steril 1998 69 1 102 6 PMID 9457942 doi 10 1016 S0015 0282 97 00445 7 引文格式1维护 显式使用等标签 link O Connor JF Kovalevskaya G Birken S et al The expression of the urinary forms of human luteinizing hormone beta fragment in various populations as assessed by a specific immunoradiometric assay Hum Reprod 1998 13 4 826 35 PMID 9619532 doi 10 1093 humrep 13 4 826 引文格式1维护 显式使用等标签 link Takahashi K Kurioka H Ozaki T et al Increased prevalence of luteinizing hormone beta subunit variant in Japanese infertility patients Hum Reprod 1999 13 12 3338 44 PMID 9886510 doi 10 1093 humrep 13 12 3338 引文格式1维护 显式使用等标签 link Elter K Erel CT Cine N et al Role of the mutations Trp8 gt Arg and Ile15 gt Thr of the human luteinizing hormone beta subunit in women with polycystic ovary syndrome Fertil Steril 1999 71 3 425 30 PMID 10065776 doi 10 1016 S0015 0282 98 00491 9 引文格式1维护 显式使用等标签 link Jiang M Pakarinen P Zhang FP et al A common polymorphic allele of the human luteinizing hormone beta subunit gene additional mutations and differential function of the promoter sequence Hum Mol Genet 1999 8 11 2037 46 PMID 10484773 doi 10 1093 hmg 8 11 2037 引文格式1维护 显式使用等标签 link 取自 https zh wikipedia org w index php title 黄体生成素b亚基 amp oldid 67774863, 维基百科，wiki，书籍，书籍，图书馆，
