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维基百科

TSFM

TSFM全称线粒体热稳定延伸因子(英語:Elongation factor Ts, mitochondrial)是由基因 TSFM 编码的蛋白质,是细菌中EF-Ts(热稳定延伸因子)的同源物[5][6]

TSFM
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名TSFM;, EFTS, EFTSMT, Ts translation elongation factor, mitochondrial
外部IDOMIM:604723 MGI:1913649 HomoloGene:4184 GeneCards:TSFM
基因位置(人类
染色体12號染色體[1]
基因座12q14.1起始57,782,761 bp[1]
终止57,808,071 bp[1]
RNA表达模式




查阅更多表达数据
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_005726
​NM_001172695
​NM_001172696
​NM_001172697

NM_025537

蛋白序列

NP_001166166
​NP_001166167
​NP_001166168
​NP_005717

NP_079813

基因位置​(UCSC)Chr 12: 57.78 – 57.81 MbChr 10: 126.85 – 126.87 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000123297 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000040521 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Xin H, Woriax V, Burkhart W, Spremulli LL. Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver. J Biol Chem. Aug 1995, 270 (29): 17243–9. PMID 7615523. doi:10.1074/jbc.270.29.17243 . 
  6. ^ . [2022-02-10]. (原始内容存档于2010-12-05). 

延伸阅读

  • Smeitink JA, Elpeleg O, Antonicka H, et al. Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs.. Am. J. Hum. Genet. 2006, 79 (5): 869–77. PMC 1698578 . PMID 17033963. doi:10.1086/508434. 
  • Antonicka H, Sasarman F, Kennaway NG, Shoubridge EA. The molecular basis for tissue specificity of the oxidative phosphorylation deficiencies in patients with mutations in the mitochondrial translation factor EFG1.. Hum. Mol. Genet. 2006, 15 (11): 1835–46. PMID 16632485. doi:10.1093/hmg/ddl106 . 
  • Maksimov VV, Arman IP, Tarantul VZ. [Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]. Genetika. 2006, 42 (2): 274–7. PMID 16583711. 
  • Gerhard DS, Wagner L, Feingold EA, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res. 2004, 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899 . 
  • Vernon JL, Burr PC, Wiley JE, Farwell MA. Assignment of the mitochondrial translation elongation factor Ts gene (TSFM) to human chromosome 12 bands q13→q14 by in situ hybridization and with somatic cell hybrids.. Cytogenet. Cell Genet. 2000, 89 (3–4): 145–6. PMID 10965106. S2CID 201991811. doi:10.1159/000015596. 
  • Bonaldo MF, Lennon G, Soares MB. Normalization and subtraction: two approaches to facilitate gene discovery. Genome Res. 1997, 6 (9): 791–806. PMID 8889548. doi:10.1101/gr.6.9.791 . 
  • Benkowski LA, Takemoto C, Ott G, et al. Interaction of mitochondrial elongation factors Tu.Ts with aminoacyl-tRNA. Nucleic Acids Symp. Ser. 1996, (33): 163–6. PMID 8643359. 

外部链接

  • Template:UCSC genome browser
  • Template:UCSC gene details

tsfm, 全称线粒体热稳定延伸因子, 英語, elongation, factor, mitochondrial, 是由基因, 编码的蛋白质, 是细菌中ef, 热稳定延伸因子, 的同源物, 已知的結構pdb直系同源搜索, pdbe, rcsbpdbid列表2cp9識別號别名, efts, eftsmt, translation, elongation, factor, mitochondrial外部idomim, 604723, 1913649, homologene, 4184, genecards, 基因位置. TSFM全称线粒体热稳定延伸因子 英語 Elongation factor Ts mitochondrial 是由基因 TSFM 编码的蛋白质 是细菌中EF Ts 热稳定延伸因子 的同源物 5 6 TSFM已知的結構PDB直系同源搜索 PDBe RCSBPDBID列表2CP9識別號别名TSFM EFTS EFTSMT Ts translation elongation factor mitochondrial外部IDOMIM 604723 MGI 1913649 HomoloGene 4184 GeneCards TSFM基因位置 人类 染色体12號染色體 1 基因座12q14 1起始57 782 761 bp 1 终止57 808 071 bp 1 基因位置 小鼠 染色体小鼠10号染色体 2 基因座10 10 D3起始126 847 441 bp 2 终止126 866 709 bp 2 RNA表达模式查阅更多表达数据基因本體分子功能 translation elongation factor activity RNA binding 血浆蛋白结合細胞組分 线粒体基质 胞內 線粒體 细胞核生物學過程 translational elongation regulation of DNA templated transcription elongation 蛋白質生物合成 mitochondrial translational elongation regulation of mitochondrial translationSources Amigo QuickGO直系同源物種人類小鼠Entrez1010266399EnsemblENSG00000123297ENSMUSG00000040521UniProtP43897Q9CZR8mRNA 序列NM 005726 NM 001172695 NM 001172696 NM 001172697NM 025537蛋白序列NP 001166166 NP 001166167 NP 001166168 NP 005717NP 079813基因位置 UCSC Chr 12 57 78 57 81 MbChr 10 126 85 126 87 MbPubMed 查找 3 4 維基數據檢視 編輯人類檢視 編輯小鼠参考文献 编辑 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000123297 Ensembl May 2017 2 0 2 1 2 2 GRCm38 Ensembl release 89 ENSMUSG00000040521 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Xin H Woriax V Burkhart W Spremulli LL Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver J Biol Chem Aug 1995 270 29 17243 9 PMID 7615523 doi 10 1074 jbc 270 29 17243 Entrez Gene TSFM Ts translation elongation factor mitochondrial 2022 02 10 原始内容存档于2010 12 05 延伸阅读 编辑Smeitink JA Elpeleg O Antonicka H et al Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs Am J Hum Genet 2006 79 5 869 77 PMC 1698578 PMID 17033963 doi 10 1086 508434 Antonicka H Sasarman F Kennaway NG Shoubridge EA The molecular basis for tissue specificity of the oxidative phosphorylation deficiencies in patients with mutations in the mitochondrial translation factor EFG1 Hum Mol Genet 2006 15 11 1835 46 PMID 16632485 doi 10 1093 hmg ddl106 Maksimov VV Arman IP Tarantul VZ Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two hybrid system Genetika 2006 42 2 274 7 PMID 16583711 Gerhard DS Wagner L Feingold EA et al The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 2004 14 10B 2121 7 PMC 528928 PMID 15489334 doi 10 1101 gr 2596504 Strausberg RL Feingold EA Grouse LH et al Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 2003 99 26 16899 903 PMC 139241 PMID 12477932 doi 10 1073 pnas 242603899 Vernon JL Burr PC Wiley JE Farwell MA Assignment of the mitochondrial translation elongation factor Ts gene TSFM to human chromosome 12 bands q13 q14 by in situ hybridization and with somatic cell hybrids Cytogenet Cell Genet 2000 89 3 4 145 6 PMID 10965106 S2CID 201991811 doi 10 1159 000015596 Bonaldo MF Lennon G Soares MB Normalization and subtraction two approaches to facilitate gene discovery Genome Res 1997 6 9 791 806 PMID 8889548 doi 10 1101 gr 6 9 791 Benkowski LA Takemoto C Ott G et al Interaction of mitochondrial elongation factors Tu Ts with aminoacyl tRNA Nucleic Acids Symp Ser 1996 33 163 6 PMID 8643359 外部链接 编辑Template UCSC genome browser Template UCSC gene details 取自 https zh wikipedia org w index php title TSFM amp oldid 71686226, 维基百科,wiki,书籍,书籍,图书馆,

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