^ 1.01.11.2GRCh38: Ensembl release 89: ENSG00000054796 - Ensembl, May 2017
^ 2.02.12.2GRCm38: Ensembl release 89: ENSMUSG00000005883 - Ensembl, May 2017
^Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^Vrielynck N, Chambon A, Vezon D, Pereira L, Chelysheva L, De Muyt A, et al. A DNA topoisomerase VI-like complex initiates meiotic recombination. Science. February 2016, 351 (6276): 939–43 [2020-08-29]. Bibcode:2016Sci...351..939V. PMID 26917763. S2CID 206643600. doi:10.1126/science.aad5196. （原始内容于2020-07-11）.
^Robert T, Nore A, Brun C, Maffre C, Crimi B, Bourbon HM, de Massy B. The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. February 2016, 351 (6276): 943–9 [2020-08-29]. Bibcode:2016Sci...351..943R. PMID 26917764. S2CID 9445593. doi:10.1126/science.aad5309. （原始内容于2020-07-11）.
十月 18, 2023
spo11, 是人类基因spo11, 编码的蛋白质, 在真核生物中广泛存在, 与古菌基因topvia为直系同源体, 负责减数第一次分裂前期遺傳重組中dna的双链断裂的形成, 識別號别名spo11, ct35, spata43, topvia, initiator, meiotic, double, stranded, breaks, spo11, initiator, meiotic, double, stranded, breaks, meiotic, recombination, meiotic, ipr013. Spo11是人类基因spo11 编码的蛋白质 在真核生物中广泛存在 与古菌基因TopVIA为直系同源体 负责减数第一次分裂前期遺傳重組中DNA的双链断裂的形成 5 6 Spo11識別號别名SPO11 CT35 SPATA43 TOPVIA initiator of meiotic double stranded breaks SPO11 initiator of meiotic double stranded breaks Meiotic recombination Spo11 Meiotic Spo11 IPR013048 Spo11 TOPOVIA外部IDOMIM 605114 MGI 1349669 HomoloGene 6059 GeneCards SPO11基因位置 人类 染色体20號染色體 1 基因座20q13 31起始57 329 803 bp 1 终止57 343 994 bp 1 基因位置 小鼠 染色体小鼠2号染色体 2 基因座2 H3 2 95 64 cM起始172 819 493 bp 2 终止172 835 369 bp 2 基因本體分子功能 金屬離子結合 催化活性 水解酶活性 ATP結合 血浆蛋白结合 isomerase activity DNA topoisomerase type II double strand cut ATP hydrolyzing activity endodeoxyribonuclease activity producing 3 phosphomonoesters DNA结合細胞組分 染色体 端粒 细胞核 nuclear chromosome生物學過程 protein localization to chromosome female gamete generation meiotic telomere clustering male meiosis I DNA代谢过程 DNA catabolic process endonucleolytic 卵子生成 homologous chromosome pairing at meiosis 減數分裂 synaptonemal complex assembly 精子发生 spermatid development ovarian follicle development meiotic DNA double strand break processing meiotic DNA double strand break formation reciprocal meiotic recombination double strand break repair involved in meiotic recombinationSources Amigo QuickGO直系同源物種人類小鼠Entrez2362626972EnsemblENSG00000054796ENSMUSG00000005883UniProtQ9Y5K1Q5TCH6Q9WTK8mRNA 序列 NM 012444 NM 198265NM 001083959 NM 001083960 NM 012046 NM 001305434蛋白序列NP 036576 NP 937998NP 001077428 NP 001077429 NP 001292363 NP 036176基因位置 UCSC Chr 20 57 33 57 34 MbChr 2 172 82 172 84 MbPubMed 查找 3 4 維基數據檢視 編輯人類檢視 編輯小鼠参考文献 编辑 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000054796 Ensembl May 2017 2 0 2 1 2 2 GRCm38 Ensembl release 89 ENSMUSG00000005883 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Vrielynck N Chambon A Vezon D Pereira L Chelysheva L De Muyt A et al A DNA topoisomerase VI like complex initiates meiotic recombination Science February 2016 351 6276 939 43 2020 08 29 Bibcode 2016Sci 351 939V PMID 26917763 S2CID 206643600 doi 10 1126 science aad5196 原始内容存档于2020 07 11 Robert T Nore A Brun C Maffre C Crimi B Bourbon HM de Massy B The TopoVIB Like protein family is required for meiotic DNA double strand break formation Science February 2016 351 6276 943 9 2020 08 29 Bibcode 2016Sci 351 943R PMID 26917764 S2CID 9445593 doi 10 1126 science aad5309 原始内容存档于2020 07 11 取自 https zh wikipedia org w index php title Spo11 amp oldid 61983080, 维基百科，wiki，书籍，书籍，图书馆，
