鳞状细胞癌抗原-2（英語：Squamous cell carcinoma antigen-2，缩写SCCA-2、SCCA2，也称为丝氨酸蛋白酶抑制剂家族B亚家族成员4，serpin family B member 4，缩写SERPINB4）是一个人类18号染色体上的基因，编码一种丝氨酸蛋白酶抑制剂蛋白，是鳞状细胞癌的肿瘤标志物[5][6][7] 。
^ 1.01.11.2GRCh38: Ensembl release 89: ENSG00000206073 - Ensembl, May 2017
^ 2.02.12.2GRCm38: Ensembl release 89: ENSMUSG00000044594 - Ensembl, May 2017
^Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci U S A. May 1995, 92 (8): 3147–51. Bibcode:1995PNAS...92.3147S. PMC 42122. PMID 7724531. doi:10.1073/pnas.92.8.3147.
^Sakata Y, Arima K, Takai T, Sakurai W, Masumoto K, Yuyama N, Suminami Y, Kishi F, Yamashita T, Kato T, Ogawa H, Fujimoto K, Matsuo Y, Sugita Y, Izuhara K. The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1. J Biol Chem. Feb 2004, 279 (7): 5081–7. PMID 14630915. doi:10.1074/jbc.M311585200.
^Entrez Gene: SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4.
外部链接编辑
The MEROPS online database for peptidases and their inhibitors: I04.009
鳞状细胞癌抗原, 英語, squamous, cell, carcinoma, antigen, 缩写scca, scca2, 也称为丝氨酸蛋白酶抑制剂家族b亚家族成员4, serpin, family, member, 缩写serpinb4, 是一个人类18号染色体上的基因, 编码一种丝氨酸蛋白酶抑制剂蛋白, 是鳞状细胞癌的肿瘤标志物, 識別號别名serpinb4, leupin, pi11, scca, scca1, scca2, serpin, family, member, 4外部idomim, 60051. 鳞状细胞癌抗原 2 英語 Squamous cell carcinoma antigen 2 缩写SCCA 2 SCCA2 也称为丝氨酸蛋白酶抑制剂家族B亚家族成员4 serpin family B member 4 缩写SERPINB4 是一个人类18号染色体上的基因 编码一种丝氨酸蛋白酶抑制剂蛋白 是鳞状细胞癌的肿瘤标志物 5 6 7 鳞状细胞癌抗原 2識別號别名SERPINB4 LEUPIN PI11 SCCA 2 SCCA1 SCCA2 serpin family B member 4外部IDOMIM 600518 MGI 3573933 HomoloGene 76659 GeneCards SERPINB4基因位置 人类 染色体18號染色體 1 基因座18q21 33起始63 637 259 bp 1 终止63 644 256 bp 1 基因位置 小鼠 染色体小鼠1号染色体 2 基因座1 1 E2 1起始106 973 317 bp 2 终止106 980 033 bp 2 基因本體分子功能 peptidase inhibitor activity 蛋白酶結合 酶结合 serine type endopeptidase inhibitor activity細胞組分 細胞質 胞內 細胞外空間生物學過程 negative regulation of peptidase activity regulation of proteolysis protection from natural killer cell mediated cytotoxicity negative regulation of endopeptidase activitySources Amigo QuickGO直系同源物種人類小鼠Entrez631820248EnsemblENSG00000206073ENSMUSG00000044594UniProtP48594无数据mRNA 序列 NM 002974 NM 175041NM 009126蛋白序列NP 002965 NP 778206无数据基因位置 UCSC Chr 18 63 64 63 64 MbChr 1 106 97 106 98 MbPubMed 查找 3 4 維基數據檢視 編輯人類檢視 編輯小鼠参考文献 编辑 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000206073 Ensembl May 2017 2 0 2 1 2 2 GRCm38 Ensembl release 89 ENSMUSG00000044594 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Schneider SS Schick C Fish KE Miller E Pena JC Treter SD Hui SM Silverman GA A serine proteinase inhibitor locus at 18q21 3 contains a tandem duplication of the human squamous cell carcinoma antigen gene Proc Natl Acad Sci U S A May 1995 92 8 3147 51 Bibcode 1995PNAS 92 3147S PMC 42122 nbsp PMID 7724531 doi 10 1073 pnas 92 8 3147 nbsp Sakata Y Arima K Takai T Sakurai W Masumoto K Yuyama N Suminami Y Kishi F Yamashita T Kato T Ogawa H Fujimoto K Matsuo Y Sugita Y Izuhara K The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen Der p 1 J Biol Chem Feb 2004 279 7 5081 7 PMID 14630915 doi 10 1074 jbc M311585200 nbsp Entrez Gene SERPINB4 serpin peptidase inhibitor clade B ovalbumin member 4 外部链接 编辑The MEROPS online database for peptidases and their inhibitors I04 009 醫學主題詞表 MeSH SERPINB4 protein human 取自 https zh wikipedia org w index php title 鳞状细胞癌抗原 2 amp oldid 76742166, 维基百科，wiki，书籍，书籍，图书馆，
