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维基百科

CDKN2C

CDKN2C,全称周期蛋白依赖性激酶4抑制蛋白C(英語:Cyclin-dependent kinase 4 inhibitor C),也称为p18蛋白,由人类基因 CDKN2C编码,是周期蛋白依赖性激酶抑制蛋白INK4家族的一员[5][6][7]

CDKN2C
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名CDKN2C;, INK4C, p18, p18-INK4C, cyclin-dependent kinase inhibitor 2C, cyclin dependent kinase inhibitor 2C
外部IDOMIM:603369 MGI:105388 HomoloGene:966 GeneCards:CDKN2C
基因位置(人类
染色体1號染色體[1]
基因座1p32.3起始50,960,745 bp[1]
终止50,974,634 bp[1]
RNA表达模式


查阅更多表达数据
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_078626
​NM_001262

NM_001301368
​NM_007671

蛋白序列

NP_001253
​NP_523240

NP_001288297
​NP_031697

基因位置​(UCSC)Chr 1: 50.96 – 50.97 MbChr 4: 109.52 – 109.52 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

参考文献 编辑

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000123080 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000028551 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Guan, K L; Jenkins, C W; Li, Y; Nichols, M A; Wu, X; O'Keefe, C L; Matera, A G; Xiong, Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.. Genes & Development. 1994-12-15, 8 (24). ISSN 0890-9369. doi:10.1101/gad.8.24.2939 (英语). 
  6. ^ Blais, Alexandre; Labrie, Yvan; Pouliot, Frédéric; Lachance, Yves; Labrie, Claude. Structure of the Gene Encoding the Human Cyclin-Dependent Kinase Inhibitor p18 and Mutational Analysis in Breast Cancer. Biochemical and Biophysical Research Communications. 1998-06-09, 247 (1). ISSN 0006-291X. doi:10.1006/bbrc.1998.8497 (英语). 
  7. ^ . [2021-08-23]. (原始内容存档于2010-12-05). 

外部链接 编辑

  • Template:UCSC genome browser
  • Template:UCSC gene details

cdkn2c, 全称周期蛋白依赖性激酶4抑制蛋白c, 英語, cyclin, dependent, kinase, inhibitor, 也称为p18蛋白, 由人类基因, 编码, 是周期蛋白依赖性激酶抑制蛋白ink4家族的一员, 已知的結構pdb直系同源搜索, pdbe, rcsbpdbid列表1bu9, 1g3n, 1ihb, 1mx2, 1mx4, 1mx6識別號别名, ink4c, ink4c, cyclin, dependent, kinase, inhibitor, cyclin, dependent, . CDKN2C 全称周期蛋白依赖性激酶4抑制蛋白C 英語 Cyclin dependent kinase 4 inhibitor C 也称为p18蛋白 由人类基因 CDKN2C编码 是周期蛋白依赖性激酶抑制蛋白INK4家族的一员 5 6 7 CDKN2C已知的結構PDB直系同源搜索 PDBe RCSBPDBID列表1BU9 1G3N 1IHB 1MX2 1MX4 1MX6識別號别名CDKN2C INK4C p18 p18 INK4C cyclin dependent kinase inhibitor 2C cyclin dependent kinase inhibitor 2C外部IDOMIM 603369 MGI 105388 HomoloGene 966 GeneCards CDKN2C基因位置 人类 染色体1號染色體 1 基因座1p32 3起始50 960 745 bp 1 终止50 974 634 bp 1 基因位置 小鼠 染色体小鼠4号染色体 2 基因座4 C7 4 51 32 cM起始109 518 073 bp 2 终止109 524 386 bp 2 RNA表达模式查阅更多表达数据基因本體分子功能 血浆蛋白结合 cyclin dependent protein serine threonine kinase inhibitor activity protein kinase binding細胞組分 細胞質 细胞质基质 细胞核生物學過程 細胞週期 regulation of cyclin dependent protein serine threonine kinase activity oligodendrocyte differentiation negative regulation of phosphorylation negative regulation of cell growth negative regulation of cell population proliferation negative regulation of cyclin dependent protein serine threonine kinase activity G1 S transition of mitotic cell cycle negative regulation of G1 S transition of mitotic cell cycleSources Amigo QuickGO直系同源物種人類小鼠Entrez103112580EnsemblENSG00000123080ENSMUSG00000028551UniProtP42773Q60772mRNA 序列NM 078626 NM 001262NM 001301368 NM 007671蛋白序列NP 001253 NP 523240NP 001288297 NP 031697基因位置 UCSC Chr 1 50 96 50 97 MbChr 4 109 52 109 52 MbPubMed 查找 3 4 維基數據檢視 編輯人類檢視 編輯小鼠参考文献 编辑 1 0 1 1 1 2 GRCh38 Ensembl release 89 ENSG00000123080 Ensembl May 2017 2 0 2 1 2 2 GRCm38 Ensembl release 89 ENSMUSG00000028551 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Guan K L Jenkins C W Li Y Nichols M A Wu X O Keefe C L Matera A G Xiong Y Growth suppression by p18 a p16INK4 MTS1 and p14INK4B MTS2 related CDK6 inhibitor correlates with wild type pRb function Genes amp Development 1994 12 15 8 24 ISSN 0890 9369 doi 10 1101 gad 8 24 2939 英语 Blais Alexandre Labrie Yvan Pouliot Frederic Lachance Yves Labrie Claude Structure of the Gene Encoding the Human Cyclin Dependent Kinase Inhibitor p18 and Mutational Analysis in Breast Cancer Biochemical and Biophysical Research Communications 1998 06 09 247 1 ISSN 0006 291X doi 10 1006 bbrc 1998 8497 英语 Entrez Gene CDKN2C cyclin dependent kinase inhibitor 2C p18 inhibits CDK4 2021 08 23 原始内容存档于2010 12 05 外部链接 编辑Template UCSC genome browser Template UCSC gene details 取自 https zh wikipedia org w index php title CDKN2C amp oldid 73840225, 维基百科,wiki,书籍,书籍,图书馆,

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