^Ballagi-Pordány, György; Köszeghy, Anna; Koltai, Mária-Zsófia; Aranyi, Zoltán; Pogátsa, Gábor. Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds. Diabetes Research and Clinical Practice. 1990, 8 (2): 109–14. PMID 2106423. doi:10.1016/0168-8227(90)90020-T.
^Shimoyama, Tatsuhiro; Yamaguchi, Shinya; Takahashi, Kazuto; Katsuta, Hidenori; Ito, Eisuke; Seki, Hiroyuki; Ushikawa, Kenji; Katahira, Hiroshi; et al. Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation. Metabolism. 2006, 55 (6): 722–30. PMID 16713429. doi:10.1016/j.metabol.2006.01.019.
^Del Guerra, S; Grupillo, M; Masini, M; Lupi, R; Bugliani, M; Torri, S; Boggi, U; Del Chiaro, M; et al. Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose. Diabetes/Metabolism Research and Reviews. 2007, 23 (3): 234–8. PMID 16952202. doi:10.1002/dmrr.680.
^Katakami, N.; Yamasaki, Y.; Hayaishi-Okano, R.; Ohtoshi, K.; Kaneto, H.; Matsuhisa, M.; Kosugi, K.; Hori, M. Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. Diabetologia. 2004, 47 (11): 1906–13. PMID 15565373. doi:10.1007/s00125-004-1547-8.
五月 09, 2024
格列齐特, 维基百科中的醫學内容仅供参考, 並不能視作專業意見, 如需獲取醫療幫助或意見, 请咨询专业人士, 詳見醫學聲明, 英語, gliclazide, 商品名为达美康, 是一种磺酰脲类口服抗糖尿病药, 可以防止因高血糖引起的细胞凋亡, 保护人体的胰岛β细胞, 还可以防止因2型糖尿病导致的动脉粥样硬化, 防止动脉脂肪堆积, 在中国作为一线药物使用, 应用极为广泛, 而在其他国家却并不常用, diamicron, gliclazide, 臨床資料商品名, 英语, drug, nomenclature, 达美康ah. 维基百科中的醫學内容仅供参考 並不能視作專業意見 如需獲取醫療幫助或意見 请咨询专业人士 詳見醫學聲明 格列齐特 英語 Gliclazide 商品名为达美康 是一种磺酰脲类口服抗糖尿病药 1 2 格列齐特可以防止因高血糖引起的细胞凋亡 保护人体的胰岛b细胞 3 格列齐特还可以防止因2型糖尿病导致的动脉粥样硬化 防止动脉脂肪堆积 4 格列齐特在中国作为一线药物使用 应用极为广泛 而在其他国家却并不常用 Diamicron Gliclazide 格列齐特臨床資料商品名 英语 Drug nomenclature 达美康AHFS Drugs comMicromedex详细消费者药物信息懷孕分級澳 C给药途径口服ATC碼A10BB09 WHO 法律規範狀態法律規範澳 限医生处方 S4 藥物動力學數據生物半衰期10 4小时识别信息IUPAC命名法 N hexahydrocyclopenta c pyrrol 2 1H ylcarbamoyl 4 methylbenzenesulfonamideCAS号21187 98 4 YPubChem CID3475DrugBankDB01120 YChemSpider3356 YUNIIG4PX8C4HKVKEGGD01599 YChEBICHEBI 31654 YChEMBLChEMBL427216 YCompTox Dashboard 英语 CompTox Chemicals Dashboard EPA DTXSID9023095ECHA InfoCard100 040 221化学信息化学式C 15H 21N 3O 3S摩尔质量323 412 g mol3D模型 JSmol 英语 JSmol 交互式图像SMILES O S O c1ccc cc1 C NC O NN3CC2CCCC2C3InChI InChI 1S C15H21N3O3S c1 11 5 7 14 8 6 11 22 20 21 17 15 19 16 18 9 12 3 2 4 13 12 10 18 h5 8 12 13H 2 4 9 10H2 1H3 H2 16 17 19 YKey BOVGTQGAOIONJV UHFFFAOYSA N Y药理 编辑格列齐特为胰島素增秘剂 通过抑制胰岛b细胞的ATP sensitive potassium channel 英语 ATP sensitive potassium channel 从而促进胰岛素的释放 引用 编辑 Ballagi Pordany Gyorgy Koszeghy Anna Koltai Maria Zsofia Aranyi Zoltan Pogatsa Gabor Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds Diabetes Research and Clinical Practice 1990 8 2 109 14 PMID 2106423 doi 10 1016 0168 8227 90 90020 T Shimoyama Tatsuhiro Yamaguchi Shinya Takahashi Kazuto Katsuta Hidenori Ito Eisuke Seki Hiroyuki Ushikawa Kenji Katahira Hiroshi et al Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation Metabolism 2006 55 6 722 30 PMID 16713429 doi 10 1016 j metabol 2006 01 019 Del Guerra S Grupillo M Masini M Lupi R Bugliani M Torri S Boggi U Del Chiaro M et al Gliclazide protects human islet beta cells from apoptosis induced by intermittent high glucose Diabetes Metabolism Research and Reviews 2007 23 3 234 8 PMID 16952202 doi 10 1002 dmrr 680 Katakami N Yamasaki Y Hayaishi Okano R Ohtoshi K Kaneto H Matsuhisa M Kosugi K Hori M Metformin or gliclazide rather than glibenclamide attenuate progression of carotid intima media thickness in subjects with type 2 diabetes Diabetologia 2004 47 11 1906 13 PMID 15565373 doi 10 1007 s00125 004 1547 8 取自 https zh wikipedia org w index php title 格列齐特 amp oldid 72715316, 维基百科，wiki，书籍，书籍，图书馆，
