^Chakravarti RN, Chakravarti D. Andrographolide, the active constituent of Andrographis paniculata Nees; a preliminary communication. Ind Med Gaz. 1951, 86 (3): 96–7. PMID 14860885.
^Wang, J; Tan, X. F.; Nguyen, V. S.; Yang, P; Zhou, J; Gao, M; Li, Z; Lim, T. K.; He, Y; Ong, C. S.; Lay, Y; Zhang, J; Zhu, G; Lai, S. L.; Ghosh, D; Mok, Y. K.; Shen, H. M.; Lin, Q. A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis. Molecular & Cellular Proteomics. 2014, 13 (3): 876–86. PMC 3945915. PMID 24445406. doi:10.1074/mcp.M113.029793.
十月 29, 2023
穿心莲内酯, andrographolide, 是一种天然类萜化合物, 分子式c20, 分离自穿心莲的茎叶, 是一种非常苦的物质, iupac名3, decahydro, hydroxy, hydroxymethyl, dimethyl, methylene, napthalenyl, ethylidene, dihydro, hydroxy, furanone识别cas号, 5508, pubchem, 5318517chemspider, 16735664smiles, c3occ, ccc1, ccc2c, . 穿心莲内酯 Andrographolide 是一种天然类萜化合物 分子式C20 H30 O5 分离自穿心莲的茎叶 1 是一种非常苦的物质 穿心莲内酯IUPAC名3 2 Decahydro 6 hydroxy 5 hydroxymethyl 5 8a dimethyl 2 methylene 1 napthalenyl ethylidene dihydro 4 hydroxy 2 3H furanone识别CAS号 5508 58 7 PubChem 5318517ChemSpider 16735664SMILES O C3OCC O C3 CCC1 C C CCC2C C CO C O CCC12CInChI 1 C20H30O5 c1 12 4 7 16 19 2 9 8 17 23 20 16 3 11 21 14 12 6 5 13 15 22 10 25 18 13 24 h5 14 17 21 23H 1 4 6 11H2 2 3H3InChIKey BOJKULTULYSRAS UHFFFAOYABChEBI 65408性质化学式 C20H30O5摩尔质量 350 45 g mol 1外观 乙醇或甲醇中析出斜方棱状或片状晶体密度 1 2317 g cm3熔点 230 231 C 503 504 K 溶解性 水 微溶若非注明 所有数据均出自标准状态 25 100 kPa 下 穿心莲内酯的相关研究涉及细胞信号传送 免疫治疗 中風等领域 2 研究显示 穿心莲内酯可通过共价修饰与NF kB和肌动蛋白等蛋白质靶点结合 3 参考资料 编辑 Chakravarti RN Chakravarti D Andrographolide the active constituent of Andrographis paniculata Nees a preliminary communication Ind Med Gaz 1951 86 3 96 7 PMID 14860885 abcamBiochemicals Andrographolide ab120636 2017 03 24 原始内容存档于2017 05 04 Wang J Tan X F Nguyen V S Yang P Zhou J Gao M Li Z Lim T K He Y Ong C S Lay Y Zhang J Zhu G Lai S L Ghosh D Mok Y K Shen H M Lin Q A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide a promising anticancer agent that suppresses tumor metastasis Molecular amp Cellular Proteomics 2014 13 3 876 86 PMC 3945915 nbsp PMID 24445406 doi 10 1074 mcp M113 029793 取自 https zh wikipedia org w index php title 穿心莲内酯 amp oldid 72621853, 维基百科,wiki,书籍,书籍,图书馆,