^Freemantle N, Cleland J, Young P, Mason J, Harrison J. beta Blockade after myocardial infarction: systematic review and meta regression analysis. BMJ. June 1999, 318 (7200): 1730–7. PMC 31101. PMID 10381708. doi:10.1136/bmj.318.7200.1730.
^Cruickshank JM. Beta blockers in hypertension. Lancet. August 2010, 376 (9739): 415; author reply 415–6. PMID 20692524. doi:10.1016/S0140-6736(10)61217-2.
^Kaplan, Norman M. Choice of therapy in primary (essential) hypertension: Clinical trials. UpToDate. October 2010.
^De Giorgi, Vincenzoa; Grazzini, Martaa; Benemei, Silviab; Marchionni, Niccolòc; Geppetti, Pierangelob; Gandini, Sarad. β-Blocker use and reduced disease progression in patients with thick melanoma: 8 years of follow-up.. Melanoma Research. June 2017, 27: 268–270 [2020-12-21]. doi:10.1097/CMR.000000000000031. （原始内容于2021-11-19）.
^Glasner, A; Avraham, R; Rosenne, E; Benish, M; Zmora, O; Shemer, S; Ben‐Eliyahu, S. Improving survival rates in two models of spon- taneous postoperative metastasis in mice by combined administration of a β‐adrenergic antagonist and a cyclooxygenase‐2 inhibitor.. Journal of Immunology. March 2010, 184: 2449–2457 [2020-12-21]. doi:10.4049/jimmunol.0903301. （原始内容于2021-11-19）.
^Childers, W. K.; Hollenbeak, C. S.; Cheriyath, P. β‐Blockers reduce breast cancer recurrence and breast cancer death: A meta‐analysis. Clinical Breast Cancer.. Clinical Breast Cancer. December 2015, 15 (6): 426–431. doi:10.1016/j.clbc.2015.07.001.
^Frishman W.H.; Cheng-Lai A; Nawarskas J. Current Cardiovascular Drugs. Current Science Group. 2005: 152 [2010-09-07]. ISBN 978-1-57340-221-7.
^Arcangelo V.P.; Peterson A.M. Pharmacotherapeutics for advanced practice: a practical approach. Lippincott Williams & Wilkins. 2006: 205 [2010-09-07]. ISBN 978-0-7817-5784-3.
^Schena, G; Caplan, M. J.; Benemei, Silviab; Marchionni, Niccolòc; Geppetti, Pierangelob; Gandini, Sarad. Everything You Always Wanted to Know about β3-AR * (* But Were Afraid to Ask). Cells. Aprail 2019, 8 (4): 357. doi:10.3390/cells8040357.请检查|date=中的日期值 (帮助)
^Williams, Bryan; Mancia, Giuseppe; Spiering, Wilko; Agabiti Rosei, Enrico; Azizi, Michel; Burnier, Michel; Clement, Denis L.; Coca, Antonio; de Simone, Giovanni. 2018 ESC/ESH Guidelines for the management of arterial hypertensionThe Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal. 2018-09-01, 39 (33): 3021–3104 [2020-01-03]. ISSN 0195-668X. doi:10.1093/eurheartj/ehy339. （原始内容于2022-03-10） （英语）.
^Kim, Jihee; Grotegut, Chad A.; Wisler, James W.; Mao, Lan; Rosenberg, Paul B.; Rockman, Howard A.; Lefkowitz, Robert J. The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility. Proceedings of the National Academy of Sciences. 2020-06-02, 117 (22): 12435–12443. doi:10.1073/pnas.1920310117.
行進 31, 2023
Β受体阻滞剂, 维基百科中的醫學内容仅供参考, 並不能視作專業意見, 如需獲取醫療幫助或意見, 请咨询专业人士, 詳見醫學聲明, β受体阻断药, 英語, beta, blockers, 又称beta受体阻断药, β受体阻断剂, β受体阻滞剂, β受体拮抗剂或β阻断药, 乙型阻斷劑, 是一类用来治疗心律不整, 防止心脏病发作后的二次心脏病发作, 二级预防, 和在某些情况下用来治疗高血压的药物, 近期有相關證據顯示, 此類阻滯劑可能具有協助癌症治療的潛能, β受体阻断药beta, blockers药物种类普萘洛尔的键线. 维基百科中的醫學内容仅供参考 並不能視作專業意見 如需獲取醫療幫助或意見 请咨询专业人士 詳見醫學聲明 b受体阻断药 英語 Beta blockers 又称Beta受体阻断药 b受体阻断剂 b受体阻滞剂 b受体拮抗剂或b阻断药 乙型阻斷劑 是一类用来治疗心律不整 防止心脏病发作后的二次心脏病发作 二级预防 和在某些情况下用来治疗高血压的药物 1 2 3 近期有相關證據顯示 此類阻滯劑可能具有協助癌症治療的潛能 4 5 6 b受体阻断药Beta blockers药物种类普萘洛尔的键线式结构 是第一种成功应用于临床的b受体阻断药用途高血压 心律不整等生物目标b受体ATC代码C07外部链接MeSHD000319AHFS Drugs com药物分类消费者报告Best Buy DrugsWebMDmedicinenet rxlistb受体阻断药非竞争性阻断交感神经系统中内源性儿茶酚胺肾上腺素和去甲肾上腺素的作用 尤其是肾上腺素能b受体 7 8 有些药物阻断所有b 肾上腺素能受体 有些则为竞争性阻断 目前 市面上的藥物多以b受體中的b1及b2為目標 而針對b3的受體阻滯劑因藥理學特性仍無法良好掌握故持續處於研究階段 9 ESC ESH指引指出對於合併心衰竭 心絞痛 心肌梗塞後或心房顫動的高血壓患者 以及育齡期或計畫懷孕的女性高血壓患者 可考慮在任何治療階段使用乙型阻斷劑 10 最近有研究證明乙型阻斷劑carvedilol可以增強骨骼肌收縮力 但卻無法導致骨骼肌肥大 該研究亦指出b2AR激動劑clenbuterol則可以增強骨骼肌收縮力和引起骨骼肌肥大的現象 而這些現象都是通過b arrestin的信號傳遞所介導的 11 例子 编辑 二氯異丙腎上腺素 英语 Dichloroisoprenaline 第一种b受体阻断药 普萘洛尔 Propranolol 毕索洛尔 Bisoprolol 引用 编辑 Freemantle N Cleland J Young P Mason J Harrison J beta Blockade after myocardial infarction systematic review and meta regression analysis BMJ June 1999 318 7200 1730 7 PMC 31101 PMID 10381708 doi 10 1136 bmj 318 7200 1730 Cruickshank JM Beta blockers in hypertension Lancet August 2010 376 9739 415 author reply 415 6 PMID 20692524 doi 10 1016 S0140 6736 10 61217 2 Kaplan Norman M Choice of therapy in primary essential hypertension Clinical trials UpToDate October 2010 De Giorgi Vincenzoa Grazzini Martaa Benemei Silviab Marchionni Niccoloc Geppetti Pierangelob Gandini Sarad b Blocker use and reduced disease progression in patients with thick melanoma 8 years of follow up Melanoma Research June 2017 27 268 270 2020 12 21 doi 10 1097 CMR 000000000000031 原始内容存档于2021 11 19 Glasner A Avraham R Rosenne E Benish M Zmora O Shemer S Ben Eliyahu S Improving survival rates in two models of spon taneous postoperative metastasis in mice by combined administration of a b adrenergic antagonist and a cyclooxygenase 2 inhibitor Journal of Immunology March 2010 184 2449 2457 2020 12 21 doi 10 4049 jimmunol 0903301 原始内容存档于2021 11 19 Childers W K Hollenbeak C S Cheriyath P b Blockers reduce breast cancer recurrence and breast cancer death A meta analysis Clinical Breast Cancer Clinical Breast Cancer December 2015 15 6 426 431 doi 10 1016 j clbc 2015 07 001 Frishman W H Cheng Lai A Nawarskas J Current Cardiovascular Drugs Current Science Group 2005 152 2010 09 07 ISBN 978 1 57340 221 7 Arcangelo V P Peterson A M Pharmacotherapeutics for advanced practice a practical approach Lippincott Williams amp Wilkins 2006 205 2010 09 07 ISBN 978 0 7817 5784 3 Schena G Caplan M J Benemei Silviab Marchionni Niccoloc Geppetti Pierangelob Gandini Sarad Everything You Always Wanted to Know about b3 AR But Were Afraid to Ask Cells Aprail 2019 8 4 357 doi 10 3390 cells8040357 请检查 date 中的日期值 帮助 Williams Bryan Mancia Giuseppe Spiering Wilko Agabiti Rosei Enrico Azizi Michel Burnier Michel Clement Denis L Coca Antonio de Simone Giovanni 2018 ESC ESH Guidelines for the management of arterial hypertensionThe Task Force for the management of arterial hypertension of the European Society of Cardiology ESC and the European Society of Hypertension ESH European Heart Journal 2018 09 01 39 33 3021 3104 2020 01 03 ISSN 0195 668X doi 10 1093 eurheartj ehy339 原始内容存档于2022 03 10 英语 Kim Jihee Grotegut Chad A Wisler James W Mao Lan Rosenberg Paul B Rockman Howard A Lefkowitz Robert J The b arrestin biased b adrenergic receptor blocker carvedilol enhances skeletal muscle contractility Proceedings of the National Academy of Sciences 2020 06 02 117 22 12435 12443 doi 10 1073 pnas 1920310117 取自 https zh wikipedia org w index php title B受体阻滞剂 amp oldid 70572950, 维基百科，wiki，书籍，书籍，图书馆，
