fbpx
维基百科

非诺特罗

非诺特罗(Fenoterol) 是一種用來擴張呼吸道β2肾上腺素受体激动药。非诺特罗 屬於拟交感神经药 β2 刺激劑和氣喘藥。

非诺特罗
臨床資料
AHFS英语American Society of Health-System Pharmacists/Drugs.comMicromedex详细消费者药物信息
给药途径Inhalation (MDI英语Metered-dose inhaler)
ATC碼
  • R03AC04 (WHO) G02CA03
法律規範狀態
法律規範
藥物動力學數據
生物半衰期6.5小時左右 [1][2][3][4]
识别信息
CAS号13392-18-2  
PubChem CID
  • 3343
IUPHAR/BPS
  • 557
DrugBank
  • DB01288 
ChemSpider
  • 3226 
UNII
  • 22M9P70OQ9
KEGG
  • D04157 
ChEBI
  • CHEBI:149226 
ChEMBL
  • ChEMBL32800 
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
  • DTXSID4023046
ECHA InfoCard100.205.960
化学信息
化学式C17H21NO4
摩尔质量303.35 g/mol
3D模型(JSmol英语JSmol
  • 交互式图像

非诺特罗 由勃林格殷格翰製造和銷售,商品名稱為:Berotec N備勞喘)。製造商有時也會把非诺特罗與ipratropium混和後銷售,商品名稱同樣為 Berotec N。

醫學用途

非诺特罗 是短效的 β2刺激劑。當非诺特罗使用超過建議的醫療用劑量(每日最多只能吸入八劑、每劑量需間隔至少五分鐘,若氣喘狀況沒好轉,則再吸入第二劑[5])時,也會成為β1 受體英语Beta-1 adrenergic receptor刺激劑。

使用者可以於運動前吸入一劑,預防稍後因運動所誘發的氣喘(氣管痙攣)。[6]

副作用

已知曾有患者在急性氣喘發作時吸入了高達80劑的非诺特罗,最終因而死亡。當患者發現非诺特罗已經無法緩解氣喘時,應當停止吸入非诺特罗,並盡快就醫。[7][8]

 
Berotec
 
Berotec 備勞喘

參見

  • 運動引起的氣喘英语Exercise-induced bronchoconstriction

文獻來源

  1. ^ Fenoterol Hydrobromide Drug Information, Professional. Drugs.com. 1996-01-01 [2018-06-11]. (原始内容于2019-08-25). 
  2. ^ Fenoterol - Drug Monograph. DrugInfoSys.com. 2016-10-27 [2018-06-11]. (原始内容于2020-11-27). 
  3. ^ Berotec Inhalation Solution (Fenoterol HBr). RxMed.com. [2018-06-11]. (原始内容于2021-04-20). 
  4. ^ Svedmyr, Nils. Fenoterol: A Beta2-adrenergic Agonist for Use in Asthma; Pharmacology, Pharmacokinetics, Clinical Efficacy and Adverse Effects. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy (Wiley). 1985-05-06, 5 (3): 109–126. ISSN 0277-0008. doi:10.1002/j.1875-9114.1985.tb03409.x. 
  5. ^ Berotec N/Concise Prescribing Info/Full Prescribing info. 2018-02-28 [2018-02-28]. (原始内容于2020-11-23). Dosage / Direction for Use:
    Acute Asthma Episodes: 1 puff is sufficient for prompt symptom relief in most cases, if breathing has not noticeably improved after 5 minutes, a second dose may be taken, up to a maximum of 8 puffs per day. If an attack has not been relieved by 2 puffs, further puffs may be required. In this situation, patients should consult the doctor or the nearest hospital immediately. (See Precautions).
    Prophylaxis of Exercise Induced Asthma: 1-2 puffs prior to exercise, up to a maximum of 8 puffs per day.
    Bronchial Asthma and Other Conditions with Reversible Airways Narrowing: If repeated dosing is required, 1-2 puffs for each administration, up to a maximum of 8 puffs per day.
     
  6. ^ Management of acute exacerbations of asthma in adults. UpToDate. [2018-06-25]. (原始内容于2018-06-25). 
  7. ^ Beasley R, Pearce N, Crane J, Burgess C. Withdrawal of 非诺特罗 and the end of the New Zealand asthma mortality epidemic. International Archives of Allergy and Immunology. 1995, 107 (1-3): 325–7. PMID 7613161. doi:10.1159/000237016. 
  8. ^ Spitzer WO, Suissa S, Ernst P, et al. The use of beta-agonists and the risk of death and near death from asthma. The New England Journal of Medicine. February 1992, 326 (8): 501–6. PMID 1346340. doi:10.1056/NEJM199202203260801. 

非诺特罗, fenoterol, 是一種用來擴張呼吸道的β2肾上腺素受体激动药, 屬於拟交感神经药, 刺激劑和氣喘藥, 臨床資料ahfs, 英语, american, society, health, system, pharmacists, drugs, commicromedex详细消费者药物信息给药途径inhalation, 英语, metered, dose, inhaler, atc碼r03ac04, g02ca03法律規範狀態法律規範澳, 限药剂师, 处方药, only, 处方药, only, 处方药,. 非诺特罗 Fenoterol 是一種用來擴張呼吸道的b2肾上腺素受体激动药 非诺特罗 屬於拟交感神经药 b2 刺激劑和氣喘藥 非诺特罗臨床資料AHFS 英语 American Society of Health System Pharmacists Drugs comMicromedex详细消费者药物信息给药途径Inhalation MDI 英语 Metered dose inhaler ATC碼R03AC04 WHO G02CA03法律規範狀態法律規範澳 限药剂师 S3 加 处方药 only 英 处方药 only POM 美 处方药 only 藥物動力學數據生物半衰期6 5小時左右 1 2 3 4 识别信息IUPAC命名法 RR SS 5 1 hydroxy 2 2 4 hydroxyphenyl 1 methylethyl amino ethyl benzene 1 3 diolCAS号13392 18 2 PubChem CID3343IUPHAR BPS557DrugBankDB01288 ChemSpider3226 UNII22M9P70OQ9KEGGD04157 ChEBICHEBI 149226 ChEMBLChEMBL32800 CompTox Dashboard 英语 CompTox Chemicals Dashboard EPA DTXSID4023046ECHA InfoCard100 205 960化学信息化学式C 17H 21N O 4摩尔质量303 35 g mol3D模型 JSmol 英语 JSmol 交互式图像SMILES Oc1cc cc O c1 C O CNC C Cc2ccc O cc2InChI InChI 1S C17H21NO4 c1 11 6 12 2 4 14 19 5 3 12 18 10 17 22 13 7 15 20 9 16 21 8 13 h2 5 7 9 11 17 22H 6 10H2 1H3 Key LSLYOANBFKQKPT UHFFFAOYSA N 提示 此条目的主题不是福莫特罗 维基百科中的醫學内容仅供参考 並不能視作專業意見 如需獲取醫療幫助或意見 请咨询专业人士 詳見醫學聲明 非诺特罗 由勃林格殷格翰製造和銷售 商品名稱為 Berotec N 備勞喘 製造商有時也會把非诺特罗與ipratropium混和後銷售 商品名稱同樣為 Berotec N 目录 1 醫學用途 1 1 副作用 2 參見 3 文獻來源醫學用途 编辑非诺特罗 是短效的 b2刺激劑 當非诺特罗使用超過建議的醫療用劑量 每日最多只能吸入八劑 每劑量需間隔至少五分鐘 若氣喘狀況沒好轉 則再吸入第二劑 5 時 也會成為b1 受體 英语 Beta 1 adrenergic receptor 刺激劑 使用者可以於運動前吸入一劑 預防稍後因運動所誘發的氣喘 氣管痙攣 6 副作用 编辑 已知曾有患者在急性氣喘發作時吸入了高達80劑的非诺特罗 最終因而死亡 當患者發現非诺特罗已經無法緩解氣喘時 應當停止吸入非诺特罗 並盡快就醫 7 8 Berotec Berotec 備勞喘參見 编辑運動引起的氣喘 英语 Exercise induced bronchoconstriction 文獻來源 编辑 Fenoterol Hydrobromide Drug Information Professional Drugs com 1996 01 01 2018 06 11 原始内容存档于2019 08 25 Fenoterol Drug Monograph DrugInfoSys com 2016 10 27 2018 06 11 原始内容存档于2020 11 27 Berotec Inhalation Solution Fenoterol HBr RxMed com 2018 06 11 原始内容存档于2021 04 20 Svedmyr Nils Fenoterol A Beta2 adrenergic Agonist for Use in Asthma Pharmacology Pharmacokinetics Clinical Efficacy and Adverse Effects Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy Wiley 1985 05 06 5 3 109 126 ISSN 0277 0008 doi 10 1002 j 1875 9114 1985 tb03409 x Berotec N Concise Prescribing Info Full Prescribing info 2018 02 28 2018 02 28 原始内容存档于2020 11 23 Dosage Direction for Use Acute Asthma Episodes 1 puff is sufficient for prompt symptom relief in most cases if breathing has not noticeably improved after 5 minutes a second dose may be taken up to a maximum of 8 puffs per day If an attack has not been relieved by 2 puffs further puffs may be required In this situation patients should consult the doctor or the nearest hospital immediately See Precautions Prophylaxis of Exercise Induced Asthma 1 2 puffs prior to exercise up to a maximum of 8 puffs per day Bronchial Asthma and Other Conditions with Reversible Airways Narrowing If repeated dosing is required 1 2 puffs for each administration up to a maximum of 8 puffs per day Management of acute exacerbations of asthma in adults UpToDate 2018 06 25 原始内容存档于2018 06 25 Beasley R Pearce N Crane J Burgess C Withdrawal of 非诺特罗 and the end of the New Zealand asthma mortality epidemic International Archives of Allergy and Immunology 1995 107 1 3 325 7 PMID 7613161 doi 10 1159 000237016 Spitzer WO Suissa S Ernst P et al The use of beta agonists and the risk of death and near death from asthma The New England Journal of Medicine February 1992 326 8 501 6 PMID 1346340 doi 10 1056 NEJM199202203260801 取自 https zh wikipedia org w index php title 非诺特罗 amp oldid 70159196, 维基百科,wiki,书籍,书籍,图书馆,

文章

,阅读,下载,免费,免费下载,mp3,视频,mp4,3gp, jpg,jpeg,gif,png,图片,音乐,歌曲,电影,书籍,游戏,游戏。