这一家族的蛋白可分为三组:一是分子量约47kDa的免疫相关鸟苷三磷酸酶(英语:IRGs)(Immunity Related Guanosine Triphosphatases,IRGs)成员包括干扰素诱导GTP酶5和免疫相关GTP酶家族M蛋白;二是MX蛋白,成员包括MX1和MX2;三是分子量为65-67kDa的鸟苷酸结合蛋白(Guanylate-binding protein,GBPs)[2]。
参考文献编辑
^Zerrahn J, Schaible UE, Brinkmann V, Guhlich U, Kaufmann SH. The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis. J. Immunol. April 2002, 168 (7): 3428–36. PMID 11907101. doi:10.4049/jimmunol.168.7.3428.
^Tripal P, Bauer M, Naschberger E, Mortinger T, Hohenadl C, Cornali E, Thurau M, Sturzl M. Unique features of different members of the human guanylate-binding protein family. J. Interferon Cytokine Res. January 2007, 27 (1): 44–52. PMID 17266443. doi:10.1089/jir.2007.0086.