交叉呈遞是特定抗原呈現細胞吞噬並利用MHC I呈現外來抗原給细胞毒性T细胞的能力。交叉致敏,是交叉呈遞後的結果,其描述的是透過交叉呈遞而使初始T細胞(英语:Naive T cell)變成活化的過程。[1] 這個過程對於大多數對抗腫瘤或病毒的免疫反應是必須的。這些腫瘤或是細胞內的病毒不會感染抗原呈現細胞,反而是感染周邊組織。[2][3]交叉呈遞對於「蛋白抗原疫苗」引起的免疫保護反應也是需要的,這類疫苗像是癌症疫苗等等。[4]
^Bevan, Michael J. Cross-priming. Nature Immunology (Nature Publishing Group). 2006, 7 (4): 363–365 [2018-05-27]. PMID 16550200. doi:10.1038/ni0406-363. (原始内容于2009-04-16).
^Heath, WR; Carbone, FR. Cross-presentation in viral immunity and self-tolerance. Nat Rev Immunol. 2001, 1 (2): 126–34. PMID 11905820. doi:10.1038/35100512.
^Rock, KL. A new foreign policy: MHC class I molecules monitor the outside world. Immunol. Today. 1996, 17 (3): 131–7. PMID 8820271. doi:10.1016/0167-5699(96)80605-0.
^Melief, CJ. Mini-review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming?. Eur J Immunol. 2003, 33 (10): 2645–54. PMID 14515248. doi:10.1002/eji.200324341.
^ 5.005.015.025.035.045.055.065.075.085.095.10Joffre, Olivier. Cross-presentation by dendritic cells (PDF). Nature Reviews Immunology. July 2012, 12 [2018-05-27]. (原始内容 (PDF)于2020-09-20).
^ 6.06.1Gutiérrez-Martínez, Enric; Planès, Remi; Anselmi, Giorgio; Reynolds, Matthew; Menezes, Shinelle; Adiko, Aimé Cézaire; Saveanu, Loredana; Guermonprez, Pierre. Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets. Frontiers in Immunology. 2015, 6 [2018-05-27]. ISSN 1664-3224. doi:10.3389/fimmu.2015.00363. (原始内容于2016-04-04) (英语).
^Bevan, MJ. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 1976, 143 (5): 1283–8. PMC 2190184. PMID 1083422. doi:10.1084/jem.143.5.1283.
^Wolkers, MC; Brouwenstijn, N; Bakker, AH; Toebes, M; Schumacher, TN. Antigen bias in T cell cross-priming. Science. 2004, 304 (5675): 1314–7. PMID 15166378. doi:10.1126/science.1096268.
^ 9.09.19.29.39.49.59.69.79.8Fehres, Cynthia M.; Unger, Wendy W. J.; Garcia-Vallejo, Juan J.; van Kooyk, Yvette. Understanding the Biology of Antigen Cross-Presentation for the Design of Vaccines Against Cancer. Frontiers in Immunology. 2014, 5. ISSN 1664-3224. doi:10.3389/fimmu.2014.00149(英语).
^Heath, William R.; Carbone, Francis R. . Nature Reviews Immunology. November 2001, 1 (2): 126–134 [2018-05-27]. ISSN 1474-1741. doi:10.1038/35100512. (原始内容存档于2022-06-17).
^Huang, AY; Golumbek, P; Ahmadzadeh, M; Jaffee, E; Pardoll, D; Levitsky, H. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science. 1994, 264 (5161): 961–5. PMID 7513904. doi:10.1126/science.7513904.
^Sigal, LJ; Crotty, S; Andino, R; Rock, KL. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature. 1999, 398 (6722): 77–80. PMID 10078533. doi:10.1038/18038.
^ 13.013.1Nopora, Katrin; Bernhard, Caroline Andree; Ried, Christine; Castello, Alejandro A.; Murphy, Kenneth M.; Marconi, Peggy; Koszinowski, Ulrich Helmut; Brocker, Thomas. MHC Class I Cross-Presentation by Dendritic Cells Counteracts Viral Immune Evasion. Frontiers in Immunology. 2012, 3 [2018-05-27]. ISSN 1664-3224. doi:10.3389/fimmu.2012.00348. (原始内容于2020-12-12) (英语).
^Lutz, Manfred B.; Kurts, Christian. Induction of peripheral CD4+ T-cell tolerance and CD8+ T-cell cross-tolerance by dendritic cells. European Journal of Immunology. 2009-09-01, 39 (9): 2325–2330 [2018-05-27]. ISSN 1521-4141. doi:10.1002/eji.200939548. (原始内容于2018-03-06).