^Istvan, E.S., Palnitkar, M., Buchanan, S.K., Deisenhofer, J. Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis. EMBO J. 2000, 19: 819–830 [2012-06-03]. PMID 10698924. doi:10.1093/emboj/19.5.819. PMCID PMC305622. （原始内容于2014-04-07）.
Bucher NLR, Overath P and Lynen F. beta-Hydroxy-beta-methylglutaryl coenzyme A reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver. Biochim. Biophys. Acta. 1960, 40: 491–501. PMID 13805544. doi:10.1016/0006-3002(60)91390-1.
DURR IF, RUDNEY H. The reduction of beta-hydroxy-beta-methyl-glutaryl coenzyme A to mevalonic acid. J. Biol. Chem. 1960, 235: 2572–8. PMID 13818862.
Kawachi T, Rudney H. Solubilization and purification of beta-hydroxy-beta-methylglutaryl coenzyme A reductase from rat liver. Biochemistry. 1970, 9 (8): 1700–5. PMID 4985697. doi:10.1021/bi00810a008.
十二月 05, 2023
羟甲基戊二酸单酰辅酶a还原酶, nadph, 此條目介紹的是nadp, 为受体的酶, 关于同名但以nad, 为受体的酶, 请见, 羟甲基戊二酸单酰辅酶a还原酶, 英語, hydroxymethylglutaryl, reductase, nadph, 页面存档备份, 存于互联网档案馆, 是一种以nad, 或nadp, 为受体, 作用于供体ch, oh基团上的氧化还原酶, 这种酶能催化以下酶促反应, 羟甲基戊二酸单酰辅酶a还原酶晶体结构, 1dq8, 命名系统命名, mevalonate, nadp, oxidore. 此條目介紹的是NADP 为受体的酶 关于同名但以NAD 为受体的酶 请见 羟甲基戊二酸单酰辅酶A还原酶 羟甲基戊二酸单酰辅酶A还原酶 NADPH 英語 hydroxymethylglutaryl CoA reductase NADPH EC 1 1 1 34 页面存档备份 存于互联网档案馆 是一种以NAD 或NADP 为受体 作用于供体CH OH基团上的氧化还原酶 这种酶能催化以下酶促反应 羟甲基戊二酸单酰辅酶A还原酶 NADPH 羟甲基戊二酸单酰辅酶A还原酶晶体结构 PDB 1dq8 1 命名系统命名 R mevalonate NADP oxidoreductase CoA acylating 缩写别名 hydroxymethylglutaryl coenzyme A reductase reduced nicotinamide adenine dinucleotide phosphate 3 hydroxy 3 methylglutaryl CoA reductase b hydroxy b methylglutaryl coenzyme A reductase hydroxymethylglutaryl CoA reductase NADPH S 3 hydroxy 3 methylglutaryl CoA reductase NADPH hydroxymethylglutaryl CoA reductase HMGCoA reductase mevalonate NADP oxidoreductase acetylating CoA 3 hydroxy 3 methylglutaryl CoA reductase NADPH hydroxymethylglutaryl CoA reductase NADPH2 识别码EC編號 1 1 1 34CAS号 9028 35 7数据库IntEnz IntEnz浏览BRENDA 英语 BRENDA BRENDA入口ExPASy 英语 ExPASy NiceZyme浏览KEGG KEGG入口MetaCyc 英语 MetaCyc 代谢路径PRIAM 英语 PRIAM enzyme specific profiles 概述PDB RCSB PDB PDBj PDBe PDBsum基因本体 AmiGO EGO搜索PMC 相关文献PubMed 相关文献 R 甲羟戊酸 CoA 2 NADP displaystyle rightleftharpoons S 3 羟基 3 甲基戊二酰辅酶A 2 NADPH 2 H 羟甲基戊二酸单酰辅酶A还原酶 NADPH 主要参与诸如胆固醇等类固醇的合成 用于降低胆固醇的他汀类药物通过抑制这种酶来发挥作用 参考文献 编辑 Istvan E S Palnitkar M Buchanan S K Deisenhofer J Crystal structure of the catalytic portion of human HMG CoA reductase insights into regulation of activity and catalysis EMBO J 2000 19 819 830 2012 06 03 PMID 10698924 doi 10 1093 emboj 19 5 819 PMCID PMC305622 原始内容存档于2014 04 07 Bucher NLR Overath P and Lynen F beta Hydroxy beta methylglutaryl coenzyme A reductase cleavage and condensing enzymes in relation to cholesterol formation in rat liver Biochim Biophys Acta 1960 40 491 501 PMID 13805544 doi 10 1016 0006 3002 60 91390 1 DURR IF RUDNEY H The reduction of beta hydroxy beta methyl glutaryl coenzyme A to mevalonic acid J Biol Chem 1960 235 2572 8 PMID 13818862 Kawachi T Rudney H Solubilization and purification of beta hydroxy beta methylglutaryl coenzyme A reductase from rat liver Biochemistry 1970 9 8 1700 5 PMID 4985697 doi 10 1021 bi00810a008 取自 https zh wikipedia org w index php title 羟甲基戊二酸单酰辅酶A还原酶 NADPH amp oldid 67758555, 维基百科，wiki，书籍，书籍，图书馆，
