维基百科
Β-生育酚
β-生育酚（英語：β-Tocopherol）是四種生育酚之一，分子式C28H48O2，是構成维生素E的化合物之一[2][3]。在氯化镁、三乙胺存在下，它和甲醛反应，得到羟基邻位甲酰化的产物；[4]它和四丁基三溴化铵反应，得到羟基邻位溴化的产物；[5]和溴-氢氧化钠反应时，则发生氧化-卤化和重排反应。[6]
| β-Tocopherol | |
|---|---|
| IUPAC名 (2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol | |
| 识别 | |
| CAS号 | 148-03-8 |
| PubChem | 86052 |
| SMILES |
|
| ChEBI | 47771 |
| 性质 | |
| 化学式 | C28H48O2 |
| 摩尔质量 | 416.68 g/mol g·mol⁻¹ |
| 沸点 | 200–210 °C（0.1 torr）[1] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
參考文獻 编辑
- ^ "Drugs - Synonyms and Properties" data were obtained from Ashgate Publishing Co. (US). 2000. ISBN 0-566-08228-4. Retrieved from SciFinder. [2021-11-21].
- ^ Food and Agriculture Organization; World Health Organization. 9. Vitamin E. Joint FAO/WHO Expert Consultation on Human Vitamin and Mineral Requirements (报告). Bangkok, Thailand: FAO Rome. 2001 [2021-11-20]. （原始内容于2022-04-01）.
- ^ Burton, G. W.; Ingold, K. U. Autoxidation of biological molecules. 1. Antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro. Journal of the American Chemical Society. 1981, 103 (21): 6472–6477. doi:10.1021/ja00411a035.
- ^ Khaled Alsabil, Guillaume Viault, Sorphon Suor-Cherer, Jean-Jacques Helesbeux, Joumaa Merza, Vincent Dumontet, Luis Manuel Peña-Rodriguez, Pascal Richomme, Denis Séraphin. Efficient ortho-formylation in vitamin E series, application to the semi-synthesis of natural 5- and 7-formyl-δ-tocotrienols revealing an unprecedented 5-bromo-7-formyl exchange. Tetrahedron. 2017-12, 73 (49): 6863–6870 [2021-11-20]. doi:10.1016/j.tet.2017.10.039. （原始内容于2018-06-15） （英语）.
- ^ Jia-fei Poon, Vijay P. Singh, Jiajie Yan, Lars Engman. Regenerable Antioxidants-Introduction of Chalcogen Substituents into Tocopherols. Chemistry - A European Journal. 2015-02-02, 21 (6): 2447–2457 [2021-11-20]. doi:10.1002/chem.201405895 （英语）.
- ^ Stefan Böhmdorfer, Anjan Patel, Andreas Hofinger, Thomas Netscher, Lars Gille, Thomas Rosenau. Bromination of Tocopherols: Oxidative Halogenations and Rearrangements. European Journal of Organic Chemistry. 2011-06, 2011 (16): 3036–3049 [2021-11-20]. doi:10.1002/ejoc.201100153 （英语）.
外部链接 编辑
- US Office of Dietary Supplements article on Vitamin E （页面存档备份，存于互联网档案馆）
- Vitamin E risk assessment （页面存档备份，存于互联网档案馆）, Expert Group on Vitamins and Minerals, UK Food Standards Agency, 2003.