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SCH-50911

SCH-50911,分子式C8H15NO3,是一种γ-氨基丁酸β受体(GABAB选择性拮抗剂[1],用于治疗酒精戒斷症候群中的震顫性譫妄而开发[2]

SCH-50911
IUPAC名
2-[(2S)-5,5-Dimethylmorpholin-2-yl]acetic acid
识别
CAS号 160415-07-6  
PubChem 5311429
ChemSpider 4470917
SMILES
 
  • O=C(O)C[C@@H]1OCC(NC1)(C)C
InChI
 
  • 1/C8H15NO3/c1-8(2)5-12-6(4-9-8)3-7(10)11/h6,9H,3-5H2,1-2H3,(H,10,11)/t6-/m0/s1
InChIKey SEYCKMQSPUVYEF-LURJTMIEBV
MeSH SCH-50911
IUPHAR配体 1075
性质
化学式 C8H15NO3
摩尔质量 173.21 g·mol−1 g·mol⁻¹
熔点 154.5 - 157 °C(271 K)
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献 编辑

  1. ^ Blythin DJ, Kuo SC, Shue HJ, McPhail AT, Chapman RW, Kreutner W, et al. Substituted morpholine-2S-acetic acid derivatives: Sch 50911 and related compounds as novel GABAB antagonists.. Bioorganic & Medicinal Chemistry Letters. July 1996, 6 (13): 1529–34. doi:10.1016/S0960-894X(96)00267-3. 
  2. ^ Quang LS, Colombo G, Lobina C, Maccioni P, Orru A, Gessa GL, et al. Evaluation for the withdrawal syndrome from gamma-hydroxybutyric acid (GHB), gamma-butyrolactone (GBL), and 1,4-butanediol (1,4-BD) in different rat lines. Annals of the New York Academy of Sciences. August 2006, 1074: 545–58. PMID 17105952. doi:10.1196/annals.1369.055. 

外部链接 编辑

50911, 分子式c8h15no3, 是一种γ, 氨基丁酸β受体, gabab, 选择性拮抗剂, 用于治疗酒精戒斷症候群中的震顫性譫妄而开发, iupac名2, dimethylmorpholin, acetic, acid识别cas号, 160415, pubchem, 5311429chemspider, 4470917smiles, 1occ, cinchi, c8h15no3, s1inchikey, seyckmqspuvyef, lurjtmiebvmesh, iuphar配体, 1075性质化学式,. SCH 50911 分子式C8H15NO3 是一种g 氨基丁酸b受体 GABAB 选择性拮抗剂 1 用于治疗酒精戒斷症候群中的震顫性譫妄而开发 2 SCH 50911IUPAC名2 2S 5 5 Dimethylmorpholin 2 yl acetic acid识别CAS号 160415 07 6 PubChem 5311429ChemSpider 4470917SMILES O C O C C H 1OCC NC1 C CInChI 1 C8H15NO3 c1 8 2 5 12 6 4 9 8 3 7 10 11 h6 9H 3 5H2 1 2H3 H 10 11 t6 m0 s1InChIKey SEYCKMQSPUVYEF LURJTMIEBVMeSH SCH 50911IUPHAR配体 1075性质化学式 C8H15NO3摩尔质量 173 21 g mol 1 g mol 熔点 154 5 157 C 271 K 若非注明 所有数据均出自标准状态 25 100 kPa 下 参考文献 编辑 Blythin DJ Kuo SC Shue HJ McPhail AT Chapman RW Kreutner W et al Substituted morpholine 2S acetic acid derivatives Sch 50911 and related compounds as novel GABAB antagonists Bioorganic amp Medicinal Chemistry Letters July 1996 6 13 1529 34 doi 10 1016 S0960 894X 96 00267 3 Quang LS Colombo G Lobina C Maccioni P Orru A Gessa GL et al Evaluation for the withdrawal syndrome from gamma hydroxybutyric acid GHB gamma butyrolactone GBL and 1 4 butanediol 1 4 BD in different rat lines Annals of the New York Academy of Sciences August 2006 1074 545 58 PMID 17105952 doi 10 1196 annals 1369 055 外部链接 编辑 取自 https zh wikipedia org w index php title SCH 50911 amp oldid 75422321, 维基百科,wiki,书籍,书籍,图书馆,

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