^Hays, Sheryl J.; Novak, Perry M.; Ortwine, Daniel F.; Bigge, Christopher F.; Colbry, Norman L.; Johnson, Graham; Lescosky, Leonard J.; Malone, Thomas C.; Michael, Andre. Synthesis and pharmacological evaluation of hexahydrofluorenamines as noncompetitive antagonists at the N-methyl-D-aspartate receptor. J Med Chem. 1993, 36 (6): 654–70. PMID 8459395. doi:10.1021/jm00058a002.
^Nicholson, Katherine L.; Balster, Robert L. Evaluation of the phencyclidine-like discriminative stimulus effects of novel NMDA channel blockers in rats. Psychopharmacology. 2003, 170 (2): 215–224. PMID 2851738. S2CID 30803162. doi:10.1007/s00213-003-1527-6.
^Bigge, Christopher F. Structural requirements for the development of potent n-methyl-d-aspartic acid (NMDA) receptor antagonists. Biochemical Pharmacology. 1993, 45 (8): 1547–1561. PMID 7683469. doi:10.1016/0006-2952(93)90294-7.
^Bigge, Christopher F.; Malone, Thomas C. Overview: Agonists, Antagonists and Modulators of the N-methyl-D-aspartic acid (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA) Subtypes of Glutamate Receptors. Current Opinion on Therapeutic Patents. 1993, 3 (7): 951–989. doi:10.1517/13543776.3.7.951.
^Polycyclic amine derivatives useful as cerebrovascular agents (页面存档备份,存于互联网档案馆) United States Patent; Coughenour, et al. Family ID: 22686445 Appl. #07/186,834
137889, 甲基六氢芴胺, 是一種化學化合物, 中枢神经系统nmda受体拮抗剂, 效力比氯胺酮強約30倍, 動物研究中可替代五氯苯酚, 氯胺酮ki, iupac名, methyl, hexahydro, fluoren, amine识别cas号, 95372, y147128, ypubchem, 10104280chemspider, 8279807smiles, c12c, cccc1, ccccc3c2inchi, c14h19n, 10h2, 1h3inchikey, kqlivvystdbtmz, u. PD 137889 N 甲基六氢芴胺 是一種化學化合物 中枢神经系统NMDA受体拮抗剂 效力比氯胺酮強約30倍 1 動物研究中可替代五氯苯酚 2 3 4 Ki 3H TCP a 27 nM 氯胺酮Ki 860 nM 5 PD 137889IUPAC名 4aR N Methyl 1 2 3 4 9 9a hexahydro 4aH fluoren 4a amine识别CAS号 95372 93 3 Y147128 60 7 rel 4aR 9aS YPubChem 10104280ChemSpider 8279807SMILES c12c cccc1 C3 NC CCCCC3C2InChI 1S C14H19N c1 15 14 9 5 4 7 12 14 10 11 6 2 3 8 13 11 14 h2 3 6 8 12 15H 4 5 7 9 10H2 1H3InChIKey KQLIVVYSTDBTMZ UHFFFAOYSA N性质化学式 C14H19N摩尔质量 201 31 g mol 1若非注明 所有数据均出自标准状态 25 100 kPa 下 参考 编辑 Hays Sheryl J Novak Perry M Ortwine Daniel F Bigge Christopher F Colbry Norman L Johnson Graham Lescosky Leonard J Malone Thomas C Michael Andre Synthesis and pharmacological evaluation of hexahydrofluorenamines as noncompetitive antagonists at the N methyl D aspartate receptor J Med Chem 1993 36 6 654 70 PMID 8459395 doi 10 1021 jm00058a002 Nicholson Katherine L Balster Robert L Evaluation of the phencyclidine like discriminative stimulus effects of novel NMDA channel blockers in rats Psychopharmacology 2003 170 2 215 224 PMID 2851738 S2CID 30803162 doi 10 1007 s00213 003 1527 6 Bigge Christopher F Structural requirements for the development of potent n methyl d aspartic acid NMDA receptor antagonists Biochemical Pharmacology 1993 45 8 1547 1561 PMID 7683469 doi 10 1016 0006 2952 93 90294 7 Bigge Christopher F Malone Thomas C Overview Agonists Antagonists and Modulators of the N methyl D aspartic acid NMDA and a amino 3 hydroxy 5 methyl 4 isoxazolepropanoic acid AMPA Subtypes of Glutamate Receptors Current Opinion on Therapeutic Patents 1993 3 7 951 989 doi 10 1517 13543776 3 7 951 Polycyclic amine derivatives useful as cerebrovascular agents 页面存档备份 存于互联网档案馆 United States Patent Coughenour et al Family ID 22686445 Appl 07 186 834 3H N 1 2 thienyl cyclohex yl piperidine 取自 https zh wikipedia org w index php title PD 137889 amp oldid 80657606, 维基百科,wiki,书籍,书籍,图书馆,