fbpx
维基百科

細菌微區室

九月 15, 2023

細菌微區室（英語：Bacterial microcompartment，BMC）是細菌中一種類胞器的結構，為多種蛋白質組成的複合體[2][3][4][5][6]，由外層的結構蛋白包裹內部的酵素，外型呈正二十面體或近似正二十面體，直徑一般介於40至200奈米之間。微區室外層的結構蛋白有類似膜的功能，將內外物質分隔，並可選擇性地讓部分物質進出[4][7][8]。

細菌微區室的結構示意圖
化學自營細菌Halothiobacillus neapolitanus的羧酶体（電子顯微鏡圖像），比例尺為100奈米[1]

羧酶体為最早被發現的細菌微區室，可促進固碳作用的微區室，內含RuBisCO和碳酸酐酶兩種酵素，此微區室是1950年代研究人員使用電子顯微鏡觀察藍菌時發現[9]，並於1973年被命名[10]。1990年代以前僅知自營細菌具有微區室，隨後漸在多種異營細菌中發現參與其他代謝作用的微區室，通稱為代謝體（metabolosome）[11][12]。不同種類的細菌微區室中的酵素不同，但外殼結構蛋白相似，一般構成蛋白六聚體（或擬六聚體）後再組成二十面體的外殼。

細菌微區室的功能示意圖：（A）自營細菌的羧酶体；（B）異營細菌的代謝體[13]

參見 编辑

  • 纳米隔室（英语：Encapsulin nanocompartment）：細菌的另一種由蛋白質組成的類胞器結構[14]
  • 氣囊泡（英语：Gas vesicle）：細菌的另一種由蛋白質組成的類胞器結構[15]


參考文獻 编辑

  1. ^ Tsai Y, Sawaya MR, Cannon GC, et al. Structural Analysis of CsoS1A and the Protein Shell of the Halothiobacillus neapolitanus Carboxysome. PLOS Biol. June 2007, 5 (6): e144. PMC 1872035  . PMID 17518518. doi:10.1371/journal.pbio.0050144. 
  2. ^ Sutter, Markus; Melnicki, Matthew R.; Schulz, Frederik; Woyke, Tanja; Kerfeld, Cheryl A. A catalog of the diversity and ubiquity of bacterial microcompartments. Nature Communications. December 2021, 12 (1): 3809. Bibcode:2021NatCo..12.3809S. ISSN 2041-1723. PMC 8217296  . PMID 34155212. doi:10.1038/s41467-021-24126-4 （英语）. 
  3. ^ Cheng, Shouqiang; Liu, Yu; Crowley, Christopher S.; Yeates, Todd O.; Bobik, Thomas A. Bacterial microcompartments: their properties and paradoxes. BioEssays. 2008, 30 (11–12): 1084–1095. ISSN 0265-9247. PMC 3272490  . PMID 18937343. doi:10.1002/bies.20830. 
  4. ^ 4.0 4.1 Kerfeld CA, Sawaya MR, Tanaka S, Nguyen CV, Phillips M, Beeby M, Yeates TO. Protein structures forming the shell of primitive bacterial organelles. Science. August 2005, 309 (5736): 936–938. Bibcode:2005Sci...309..936K. CiteSeerX 10.1.1.1026.896  . PMID 16081736. S2CID 24561197. doi:10.1126/science.1113397. 
  5. ^ Yeates, Todd O.; Kerfeld, Cheryl A.; Heinhorst, Sabine; Cannon, Gordon C.; Shively, Jessup M. Protein-based organelles in bacteria: carboxysomes and related microcompartments. Nature Reviews Microbiology. 2008, 6 (9): 681–691. ISSN 1740-1526. PMID 18679172. S2CID 22666203. doi:10.1038/nrmicro1913. 
  6. ^ Heinhorst, Sabine; Cannon, Gordon C., Jendrossek, Dieter , 编, Bacterial Microcompartments, Bacterial Organelles and Organelle-like Inclusions 34 (Cham: Springer International Publishing), 2020, 34: 125–147 [2021-09-17], ISBN 978-3-030-60172-0, S2CID 240735306, doi:10.1007/978-3-030-60173-7_6 （英语） 
  7. ^ Kerfeld, Cheryl A.; Erbilgin, Onur. Bacterial microcompartments and the modular construction of microbial metabolism. Trends in Microbiology. 2015, 23 (1): 22–34. ISSN 0966-842X. PMID 25455419. doi:10.1016/j.tim.2014.10.003  . 
  8. ^ Kerfeld, Cheryl A.; Heinhorst, Sabine; Cannon, Gordon C. Bacterial Microcompartments. Annual Review of Microbiology (Submitted manuscript). 2010, 64 (1): 391–408 [2022-11-16]. ISSN 0066-4227. PMC 6022854  . PMID 20825353. doi:10.1146/annurev.micro.112408.134211. （原始内容于2022-11-16）. 
  9. ^ G. DREWS & W. NIKLOWITZ. [Cytology of Cyanophycea. II. Centroplasm and granular inclusions of Phormidium uncinatum]. Archiv für Mikrobiologie. 1956, 24 (2): 147–162. PMID 13327992. 
  10. ^ Shively JM, Ball F, Brown DH, Saunders RE. Functional organelles in prokaryotes: polyhedral inclusions (carboxysomes) of Thiobacillus neapolitanus. Science. November 1973, 182 (4112): 584–586. Bibcode:1973Sci...182..584S. PMID 4355679. S2CID 10097616. doi:10.1126/science.182.4112.584. 
  11. ^ P. Chen, D. I. Andersson & J. R. Roth. The control region of the pdu/cob regulon in Salmonella typhimurium. Journal of Bacteriology. September 1994, 176 (17): 5474–5482. PMC 196736  . PMID 8071226. doi:10.1128/jb.176.17.5474-5482.1994. 
  12. ^ Brinsmade, S. R.; Paldon, T.; Escalante-Semerena, J. C. Minimal Functions and Physiological Conditions Required for Growth of Salmonella enterica on Ethanolamine in the Absence of the Metabolosome. Journal of Bacteriology. 2005, 187 (23): 8039–8046. ISSN 0021-9193. PMC 1291257  . PMID 16291677. doi:10.1128/JB.187.23.8039-8046.2005. 
  13. ^ Axen, Seth D.; Erbilgin, Onur; Kerfeld, Cheryl A. A Taxonomy of Bacterial Microcompartment Loci Constructed by a Novel Scoring Method. PLOS Computational Biology. 2014, 10 (10): e1003898. Bibcode:2014PLSCB..10E3898A. ISSN 1553-7358. PMC 4207490  . PMID 25340524. doi:10.1371/journal.pcbi.1003898. 
  14. ^ Sutter, Markus; Boehringer, Daniel; Gutmann, Sascha; Günther, Susanne; Prangishvili, David; Loessner, Martin J; Stetter, Karl O; Weber-Ban, Eilika; Ban, Nenad. Structural basis of enzyme encapsulation into a bacterial nanocompartment. Nature Structural & Molecular Biology. 2008, 15 (9): 939–947. ISSN 1545-9993. PMID 19172747. S2CID 205522743. doi:10.1038/nsmb.1473. hdl:20.500.11850/150838  . 
  15. ^ Pfeifer, Felicitas. Distribution, formation and regulation of gas vesicles. Nature Reviews Microbiology. 2012, 10 (10): 705–715. ISSN 1740-1526. PMID 22941504. S2CID 9926129. doi:10.1038/nrmicro2834. 

九月 15, 2023
細菌微區室, 英語, bacterial, microcompartment, 是細菌中一種類胞器的結構, 為多種蛋白質組成的複合體, 由外層的結構蛋白包裹內部的酵素, 外型呈正二十面體或近似正二十面體, 直徑一般介於40至200奈米之間, 微區室外層的結構蛋白有類似膜的功能, 將內外物質分隔, 並可選擇性地讓部分物質進出, 的結構示意圖化學自營細菌halothiobacillus, neapolitanus的羧酶体, 電子顯微鏡圖像, 比例尺為100奈米, 羧酶体為最早被發現的, 可促進固碳作用的微區室, 內含r. 細菌微區室 英語 Bacterial microcompartment BMC 是細菌中一種類胞器的結構 為多種蛋白質組成的複合體 2 3 4 5 6 由外層的結構蛋白包裹內部的酵素 外型呈正二十面體或近似正二十面體 直徑一般介於40至200奈米之間 微區室外層的結構蛋白有類似膜的功能 將內外物質分隔 並可選擇性地讓部分物質進出 4 7 8 細菌微區室的結構示意圖化學自營細菌Halothiobacillus neapolitanus的羧酶体 電子顯微鏡圖像 比例尺為100奈米 1 羧酶体為最早被發現的細菌微區室 可促進固碳作用的微區室 內含RuBisCO和碳酸酐酶兩種酵素 此微區室是1950年代研究人員使用電子顯微鏡觀察藍菌時發現 9 並於1973年被命名 10 1990年代以前僅知自營細菌具有微區室 隨後漸在多種異營細菌中發現參與其他代謝作用的微區室 通稱為代謝體 metabolosome 11 12 不同種類的細菌微區室中的酵素不同 但外殼結構蛋白相似 一般構成蛋白六聚體 或擬六聚體 後再組成二十面體的外殼 細菌微區室的功能示意圖 A 自營細菌的羧酶体 B 異營細菌的代謝體 13 參見 编辑纳米隔室 英语 Encapsulin nanocompartment 細菌的另一種由蛋白質組成的類胞器結構 14 氣囊泡 英语 Gas vesicle 細菌的另一種由蛋白質組成的類胞器結構 15 參考文獻 编辑 nbsp 分子与细胞生物学主题 Tsai Y Sawaya MR Cannon GC et al Structural Analysis of CsoS1A and the Protein Shell of the Halothiobacillus neapolitanus Carboxysome PLOS Biol June 2007 5 6 e144 PMC 1872035 nbsp PMID 17518518 doi 10 1371 journal pbio 0050144 Sutter Markus Melnicki Matthew R Schulz Frederik Woyke Tanja Kerfeld Cheryl A A catalog of the diversity and ubiquity of bacterial microcompartments Nature Communications December 2021 12 1 3809 Bibcode 2021NatCo 12 3809S ISSN 2041 1723 PMC 8217296 nbsp PMID 34155212 doi 10 1038 s41467 021 24126 4 英语 Cheng Shouqiang Liu Yu Crowley Christopher S Yeates Todd O Bobik Thomas A Bacterial microcompartments their properties and paradoxes BioEssays 2008 30 11 12 1084 1095 ISSN 0265 9247 PMC 3272490 nbsp PMID 18937343 doi 10 1002 bies 20830 4 0 4 1 Kerfeld CA Sawaya MR Tanaka S Nguyen CV Phillips M Beeby M Yeates TO Protein structures forming the shell of primitive bacterial organelles Science August 2005 309 5736 936 938 Bibcode 2005Sci 309 936K CiteSeerX 10 1 1 1026 896 nbsp PMID 16081736 S2CID 24561197 doi 10 1126 science 1113397 Yeates Todd O Kerfeld Cheryl A Heinhorst Sabine Cannon Gordon C Shively Jessup M Protein based organelles in bacteria carboxysomes and related microcompartments Nature Reviews Microbiology 2008 6 9 681 691 ISSN 1740 1526 PMID 18679172 S2CID 22666203 doi 10 1038 nrmicro1913 Heinhorst Sabine Cannon Gordon C Jendrossek Dieter 编 Bacterial Microcompartments Bacterial Organelles and Organelle like Inclusions 34 Cham Springer International Publishing 2020 34 125 147 2021 09 17 ISBN 978 3 030 60172 0 S2CID 240735306 doi 10 1007 978 3 030 60173 7 6 英语 Kerfeld Cheryl A Erbilgin Onur Bacterial microcompartments and the modular construction of microbial metabolism Trends in Microbiology 2015 23 1 22 34 ISSN 0966 842X PMID 25455419 doi 10 1016 j tim 2014 10 003 nbsp Kerfeld Cheryl A Heinhorst Sabine Cannon Gordon C Bacterial Microcompartments Annual Review of Microbiology Submitted manuscript 2010 64 1 391 408 2022 11 16 ISSN 0066 4227 PMC 6022854 nbsp PMID 20825353 doi 10 1146 annurev micro 112408 134211 原始内容存档于2022 11 16 G DREWS amp W NIKLOWITZ Cytology of Cyanophycea II Centroplasm and granular inclusions of Phormidium uncinatum Archiv fur Mikrobiologie 1956 24 2 147 162 PMID 13327992 Shively JM Ball F Brown DH Saunders RE Functional organelles in prokaryotes polyhedral inclusions carboxysomes of Thiobacillus neapolitanus Science November 1973 182 4112 584 586 Bibcode 1973Sci 182 584S PMID 4355679 S2CID 10097616 doi 10 1126 science 182 4112 584 P Chen D I Andersson amp J R Roth The control region of the pdu cob regulon in Salmonella typhimurium Journal of Bacteriology September 1994 176 17 5474 5482 PMC 196736 nbsp PMID 8071226 doi 10 1128 jb 176 17 5474 5482 1994 Brinsmade S R Paldon T Escalante Semerena J C Minimal Functions and Physiological Conditions Required for Growth of Salmonella enterica on Ethanolamine in the Absence of the Metabolosome Journal of Bacteriology 2005 187 23 8039 8046 ISSN 0021 9193 PMC 1291257 nbsp PMID 16291677 doi 10 1128 JB 187 23 8039 8046 2005 Axen Seth D Erbilgin Onur Kerfeld Cheryl A A Taxonomy of Bacterial Microcompartment Loci Constructed by a Novel Scoring Method PLOS Computational Biology 2014 10 10 e1003898 Bibcode 2014PLSCB 10E3898A ISSN 1553 7358 PMC 4207490 nbsp PMID 25340524 doi 10 1371 journal pcbi 1003898 Sutter Markus Boehringer Daniel Gutmann Sascha Gunther Susanne Prangishvili David Loessner Martin J Stetter Karl O Weber Ban Eilika Ban Nenad Structural basis of enzyme encapsulation into a bacterial nanocompartment Nature Structural amp Molecular Biology 2008 15 9 939 947 ISSN 1545 9993 PMID 19172747 S2CID 205522743 doi 10 1038 nsmb 1473 hdl 20 500 11850 150838 nbsp Pfeifer Felicitas Distribution formation and regulation of gas vesicles Nature Reviews Microbiology 2012 10 10 705 715 ISSN 1740 1526 PMID 22941504 S2CID 9926129 doi 10 1038 nrmicro2834 取自 https zh wikipedia org w index php title 細菌微區室 amp oldid 75102669, 维基百科，wiki，书籍，书籍，图书馆，

文章

，阅读，下载，免费，免费下载，mp3，视频，mp4，3gp， jpg，jpeg，gif，png，图片，音乐，歌曲，电影，书籍，游戏，游戏。