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维基百科

腺苷A2B受體

九月 25, 2023


腺苷A2B受體(Adenosine A2B receptor)，也稱為ADORA2B，是腺苷受體其中的一種G蛋白偶聯受體，也表示編碼它的人類腺苷A2b受體基因。[1]

參考資料 编辑

  1. ^ Entrez Gene: ADORA2B adenosine A2b receptor. 

延伸閱讀 编辑

  • Stiles GL. Adenosine receptors.. J. Biol. Chem. 1992, 267 (10): 6451–4. PMID 1551861. 
  • Pierce KD, Furlong TJ, Selbie LA, Shine J. Molecular cloning and expression of an adenosine A2b receptor from human brain.. Biochem. Biophys. Res. Commun. 1992, 187 (1): 86–93. PMID 1325798. doi:10.1016/S0006-291X(05)81462-7. 
  • Li Q, Han X, Lan X, Hong X, Li Q, Gao Y, Luo T, Yang Q, Koehler RC, Zhai Y, Zhou J, Wang J. Inhibition of tPA-induced hemorrhagic transformation involves adenosine A2b receptor activation after cerebral ischemia.. Neurobiology of Disease. 2017, 108: 173–182. PMC 5675803  . PMID 28830843. doi:10.1016/j.nbd.2017.08.011. 
  • Jacobson MA, Johnson RG, Luneau CJ, Salvatore CA. Cloning and chromosomal localization of the human A2b adenosine receptor gene (ADORA2B) and its pseudogene.. Genomics. 1995, 27 (2): 374–6. PMID 7558011. doi:10.1006/geno.1995.1061. 
  • Townsend-Nicholson A, Baker E, Sutherland GR, Schofield PR. Localization of the adenosine A2b receptor subtype gene (ADORA2B) to chromosome 17p11.2-p12 by FISH and PCR screening of somatic cell hybrids.. Genomics. 1995, 25 (2): 605–7. PMID 7790006. doi:10.1016/0888-7543(95)80074-V. 
  • Strohmeier GR, Reppert SM, Lencer WI, Madara JL. The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia.. J. Biol. Chem. 1995, 270 (5): 2387–94. PMID 7836474. doi:10.1074/jbc.270.5.2387  . 
  • Feoktistov I, Murray JJ, Biaggioni I. Positive modulation of intracellular Ca2+ levels by adenosine A2b receptors, prostacyclin, and prostaglandin E1 via a cholera toxin-sensitive mechanism in human erythroleukemia cells.. Mol. Pharmacol. 1994, 45 (6): 1160–7. PMID 8022409. 
  • Mirabet M, Herrera C, Cordero OJ, et al. Expression of A2B adenosine receptors in human lymphocytes: their role in T cell activation.. J. Cell Sci. 1999, 112 (4): 491–502. PMID 9914161. 
  • Feoktistov I, Goldstein AE, Biaggioni I. Role of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinase kinase in adenosine A2B receptor-mediated interleukin-8 production in human mast cells.. Mol. Pharmacol. 1999, 55 (4): 726–34. PMID 10101031. 
  • Corset V, Nguyen-Ba-Charvet KT, Forcet C, et al. Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor.. Nature. 2000, 407 (6805): 747–50. PMID 11048721. S2CID 4423128. doi:10.1038/35037600. 
  • Herrera C, Casadó V, Ciruela F, et al. Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells.. Mol. Pharmacol. 2001, 59 (1): 127–34. PMID 11125033. doi:10.1124/mol.59.1.127. 
  • Christofi FL, Zhang H, Yu JG, et al. Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system.. J. Comp. Neurol. 2001, 439 (1): 46–64. PMID 11579381. S2CID 46222306. doi:10.1002/cne.1334. 
  • Hayallah AM, Sandoval-Ramírez J, Reith U, et al. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.. J. Med. Chem. 2002, 45 (7): 1500–10. PMID 11906291. doi:10.1021/jm011049y. 
  • Sitaraman SV, Wang L, Wong M, et al. The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation.. J. Biol. Chem. 2002, 277 (36): 33188–95. PMID 12080047. doi:10.1074/jbc.M202522200  . 
  • Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proceedings of the National Academy of Sciences of the United States of America. 2003, 99 (26): 16899–903. PMC 139241  . PMID 12477932. doi:10.1073/pnas.242603899. 
  • Feoktistov I, Ryzhov S, Goldstein AE, Biaggioni I. Mast cell-mediated stimulation of angiogenesis: cooperative interaction between A2B and A3 adenosine receptors.. Circ. Res. 2003, 92 (5): 485–92. PMID 12600879. doi:10.1161/01.RES.0000061572.10929.2D  . 
  • Eltzschig HK, Ibla JC, Furuta GT, et al. Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors.. J. Exp. Med. 2003, 198 (5): 783–96. PMC 2194189  . PMID 12939345. doi:10.1084/jem.20030891. 
  • Ryzhov S, Goldstein AE, Matafonov A, et al. Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma.. J. Immunol. 2004, 172 (12): 7726–33. PMID 15187156. doi:10.4049/jimmunol.172.12.7726  . 
  • Gerhard DS, Wagner L, Feingold EA, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res. 2004, 14 (10B): 2121–7. PMC 528928  . PMID 15489334. doi:10.1101/gr.2596504. 
  • Kolachala V, Asamoah V, Wang L, et al. Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase.. J. Biol. Chem. 2005, 280 (6): 4048–57. PMID 15550390. doi:10.1074/jbc.M409577200  . 

外部連結 编辑

  • Adenosine Receptors: A2B. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. （原始内容于2016-03-03）. 
  • Human ADORA2B genome location and ADORA2B gene details page in the UCSC Genome Browser（英语：UCSC Genome Browser）.

九月 25, 2023
腺苷a, 受體, 此條目目前正依照en, adenosine, receptor上的内容进行翻译, 2020年11月1日, 如果您擅长翻译, 並清楚本條目的領域, 欢迎协助翻譯, 改善或校对本條目, 此外, 长期闲置, 未翻譯或影響閱讀的内容可能会被移除, 此條目可参照英語維基百科相應條目来扩充, 若您熟悉来源语言和主题, 请协助参考外语维基百科扩充条目, 请勿直接提交机械翻译, 也不要翻译不可靠, 低品质内容, 依版权协议, 译文需在编辑摘要注明来源, 或于讨论页顶部标记, href, template, tra. 此條目目前正依照en Adenosine A2B receptor上的内容进行翻译 2020年11月1日 如果您擅长翻译 並清楚本條目的領域 欢迎协助翻譯 改善或校对本條目 此外 长期闲置 未翻譯或影響閱讀的内容可能会被移除 此條目可参照英語維基百科相應條目来扩充 若您熟悉来源语言和主题 请协助参考外语维基百科扩充条目 请勿直接提交机械翻译 也不要翻译不可靠 低品质内容 依版权协议 译文需在编辑摘要注明来源 或于讨论页顶部标记 a href Template Translated page html title Template Translated page Translated page a 标签 腺苷A2B受體 Adenosine A2B receptor 也稱為ADORA2B 是腺苷受體其中的一種G蛋白偶聯受體 也表示編碼它的人類腺苷A2b受體基因 1 參考資料 编辑 Entrez Gene ADORA2B adenosine A2b receptor 延伸閱讀 编辑Stiles GL Adenosine receptors J Biol Chem 1992 267 10 6451 4 PMID 1551861 Pierce KD Furlong TJ Selbie LA Shine J Molecular cloning and expression of an adenosine A2b receptor from human brain Biochem Biophys Res Commun 1992 187 1 86 93 PMID 1325798 doi 10 1016 S0006 291X 05 81462 7 Li Q Han X Lan X Hong X Li Q Gao Y Luo T Yang Q Koehler RC Zhai Y Zhou J Wang J Inhibition of tPA induced hemorrhagic transformation involves adenosine A2b receptor activation after cerebral ischemia Neurobiology of Disease 2017 108 173 182 PMC 5675803 nbsp PMID 28830843 doi 10 1016 j nbd 2017 08 011 Jacobson MA Johnson RG Luneau CJ Salvatore CA Cloning and chromosomal localization of the human A2b adenosine receptor gene ADORA2B and its pseudogene Genomics 1995 27 2 374 6 PMID 7558011 doi 10 1006 geno 1995 1061 Townsend Nicholson A Baker E Sutherland GR Schofield PR Localization of the adenosine A2b receptor subtype gene ADORA2B to chromosome 17p11 2 p12 by FISH and PCR screening of somatic cell hybrids Genomics 1995 25 2 605 7 PMID 7790006 doi 10 1016 0888 7543 95 80074 V Strohmeier GR Reppert SM Lencer WI Madara JL The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia J Biol Chem 1995 270 5 2387 94 PMID 7836474 doi 10 1074 jbc 270 5 2387 nbsp Feoktistov I Murray JJ Biaggioni I Positive modulation of intracellular Ca2 levels by adenosine A2b receptors prostacyclin and prostaglandin E1 via a cholera toxin sensitive mechanism in human erythroleukemia cells Mol Pharmacol 1994 45 6 1160 7 PMID 8022409 Mirabet M Herrera C Cordero OJ et al Expression of A2B adenosine receptors in human lymphocytes their role in T cell activation J Cell Sci 1999 112 4 491 502 PMID 9914161 Feoktistov I Goldstein AE Biaggioni I Role of p38 mitogen activated protein kinase and extracellular signal regulated protein kinase kinase in adenosine A2B receptor mediated interleukin 8 production in human mast cells Mol Pharmacol 1999 55 4 726 34 PMID 10101031 Corset V Nguyen Ba Charvet KT Forcet C et al Netrin 1 mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor Nature 2000 407 6805 747 50 PMID 11048721 S2CID 4423128 doi 10 1038 35037600 Herrera C Casado V Ciruela F et al Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells Mol Pharmacol 2001 59 1 127 34 PMID 11125033 doi 10 1124 mol 59 1 127 Christofi FL Zhang H Yu JG et al Differential gene expression of adenosine A1 A2a A2b and A3 receptors in the human enteric nervous system J Comp Neurol 2001 439 1 46 64 PMID 11579381 S2CID 46222306 doi 10 1002 cne 1334 Hayallah AM Sandoval Ramirez J Reith U et al 1 8 disubstituted xanthine derivatives synthesis of potent A2B selective adenosine receptor antagonists J Med Chem 2002 45 7 1500 10 PMID 11906291 doi 10 1021 jm011049y Sitaraman SV Wang L Wong M et al The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation J Biol Chem 2002 277 36 33188 95 PMID 12080047 doi 10 1074 jbc M202522200 nbsp Strausberg RL Feingold EA Grouse LH et al Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proceedings of the National Academy of Sciences of the United States of America 2003 99 26 16899 903 PMC 139241 nbsp PMID 12477932 doi 10 1073 pnas 242603899 Feoktistov I Ryzhov S Goldstein AE Biaggioni I Mast cell mediated stimulation of angiogenesis cooperative interaction between A2B and A3 adenosine receptors Circ Res 2003 92 5 485 92 PMID 12600879 doi 10 1161 01 RES 0000061572 10929 2D nbsp Eltzschig HK Ibla JC Furuta GT et al Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium role of ectonucleotidases and adenosine A2B receptors J Exp Med 2003 198 5 783 96 PMC 2194189 nbsp PMID 12939345 doi 10 1084 jem 20030891 Ryzhov S Goldstein AE Matafonov A et al Adenosine activated mast cells induce IgE synthesis by B lymphocytes an A2B mediated process involving Th2 cytokines IL 4 and IL 13 with implications for asthma J Immunol 2004 172 12 7726 33 PMID 15187156 doi 10 4049 jimmunol 172 12 7726 nbsp Gerhard DS Wagner L Feingold EA et al The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 2004 14 10B 2121 7 PMC 528928 nbsp PMID 15489334 doi 10 1101 gr 2596504 Kolachala V Asamoah V Wang L et al Interferon gamma down regulates adenosine 2b receptor mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase J Biol Chem 2005 280 6 4048 57 PMID 15550390 doi 10 1074 jbc M409577200 nbsp 外部連結 编辑Adenosine Receptors A2B IUPHAR Database of Receptors and Ion Channels International Union of Basic and Clinical Pharmacology 原始内容存档于2016 03 03 Human ADORA2B genome location and ADORA2B gene details page in the UCSC Genome Browser 英语 UCSC Genome Browser 取自 https zh wikipedia org w index php title 腺苷A2B受體 amp oldid 74980630, 维基百科，wiki，书籍，书籍，图书馆，

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